(data stored in SCRATCH zone)

SWISSPROT: D1YW55_METPS

ID   D1YW55_METPS            Unreviewed;        79 AA.
AC   D1YW55;
DT   09-FEB-2010, integrated into UniProtKB/TrEMBL.
DT   09-FEB-2010, sequence version 1.
DT   11-DEC-2019, entry version 52.
DE   RecName: Full=Translation initiation factor 1A {ECO:0000256|HAMAP-Rule:MF_00216};
DE            Short=aIF-1A {ECO:0000256|HAMAP-Rule:MF_00216};
GN   Name=aif1a-1 {ECO:0000313|EMBL:BAI60677.1};
GN   Synonyms=eif1a {ECO:0000256|HAMAP-Rule:MF_00216};
GN   OrderedLocusNames=MCP_0605 {ECO:0000313|EMBL:BAI60677.1};
OS   Methanocella paludicola (strain DSM 17711 / JCM 13418 / NBRC 101707 /
OS   SANAE).
OC   Archaea; Euryarchaeota; Stenosarchaea group; Methanomicrobia;
OC   Methanocellales; Methanocellaceae; Methanocella.
OX   NCBI_TaxID=304371 {ECO:0000313|EMBL:BAI60677.1, ECO:0000313|Proteomes:UP000001882};
RN   [1] {ECO:0000313|Proteomes:UP000001882}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 17711 / JCM 13418 / NBRC 101707 / SANAE
RC   {ECO:0000313|Proteomes:UP000001882};
RX   PubMed=21829548; DOI=10.1371/journal.pone.0022898;
RA   Sakai S., Takaki Y., Shimamura S., Sekine M., Tajima T., Kosugi H.,
RA   Ichikawa N., Tasumi E., Hiraki A.T., Shimizu A., Kato Y., Nishiko R.,
RA   Mori K., Fujita N., Imachi H., Takai K.;
RT   "Genome sequence of a mesophilic hydrogenotrophic methanogen Methanocella
RT   paludicola, the first cultivated representative of the order
RT   Methanocellales.";
RL   PLoS ONE 6:E22898-E22898(2011).
CC   -!- FUNCTION: Seems to be required for maximal rate of protein
CC       biosynthesis. Enhances ribosome dissociation into subunits and
CC       stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal
CC       subunits. {ECO:0000256|HAMAP-Rule:MF_00216,
CC       ECO:0000256|RuleBase:RU004365}.
CC   -!- SIMILARITY: Belongs to the eIF-1A family. {ECO:0000256|HAMAP-
CC       Rule:MF_00216, ECO:0000256|RuleBase:RU004364}.
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DR   EMBL; AP011532; BAI60677.1; -; Genomic_DNA.
DR   STRING; 304371.MCP_0605; -.
DR   EnsemblBacteria; BAI60677; BAI60677; MCP_0605.
DR   KEGG; mpd:MCP_0605; -.
DR   PATRIC; fig|304371.9.peg.622; -.
DR   eggNOG; arCOG01179; Archaea.
DR   eggNOG; COG0361; LUCA.
DR   HOGENOM; HOG000223676; -.
DR   KO; K03236; -.
DR   OMA; LGGNHVR; -.
DR   Proteomes; UP000001882; Chromosome.
DR   GO; GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-UniRule.
DR   CDD; cd05793; S1_IF1A; 1.
DR   HAMAP; MF_00216; aIF_1A; 1.
DR   InterPro; IPR012340; NA-bd_OB-fold.
DR   InterPro; IPR006196; RNA-binding_domain_S1_IF1.
DR   InterPro; IPR001253; TIF_eIF-1A.
DR   InterPro; IPR018104; TIF_eIF-1A_CS.
DR   PANTHER; PTHR21668; PTHR21668; 1.
DR   Pfam; PF01176; eIF-1a; 1.
DR   SMART; SM00652; eIF1a; 1.
DR   SUPFAM; SSF50249; SSF50249; 1.
DR   TIGRFAMs; TIGR00523; eIF-1A; 1.
DR   PROSITE; PS01262; IF1A; 1.
DR   PROSITE; PS50832; S1_IF1_TYPE; 1.
PE   3: Inferred from homology;
DR   PRODOM; D1YW55.
DR   SWISS-2DPAGE; D1YW55.
KW   Initiation factor {ECO:0000256|HAMAP-Rule:MF_00216, ECO:0000256|PROSITE-
KW   ProRule:PRU00181, ECO:0000256|RuleBase:RU004365,
KW   ECO:0000313|EMBL:BAI60677.1};
KW   Protein biosynthesis {ECO:0000256|HAMAP-Rule:MF_00216, ECO:0000256|PROSITE-
KW   ProRule:PRU00181, ECO:0000256|RuleBase:RU004365};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001882}.
FT   DOMAIN          1..63
FT                   /note="S1-like"
FT                   /evidence="ECO:0000259|PROSITE:PS50832"
SQ   SEQUENCE   79 AA;  9090 MW;  7844C9717D72B3C3 CRC64;
     MLGTVISMLG ASRVVVRCID GVTRMCRIRG KMKKRVWVRE GDVVIVVPWE IQDEKGDVVW
     RYTGPQVSWL ERKGFLKNA
//

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