(data stored in ACNUC1104 zone)

SWISSPROT: D2B973_STRRD

ID   D2B973_STRRD            Unreviewed;       478 AA.
AC   D2B973;
DT   09-FEB-2010, integrated into UniProtKB/TrEMBL.
DT   09-FEB-2010, sequence version 1.
DT   08-MAY-2019, entry version 57.
DE   SubName: Full=EmrB/QacA family drug resistance transporter {ECO:0000313|EMBL:ACZ91618.1};
GN   OrderedLocusNames=Sros_8987 {ECO:0000313|EMBL:ACZ91618.1};
OS   Streptosporangium roseum (strain ATCC 12428 / DSM 43021 / JCM 3005 /
OS   NI 9100).
OC   Bacteria; Actinobacteria; Streptosporangiales; Streptosporangiaceae;
OC   Streptosporangium.
OX   NCBI_TaxID=479432 {ECO:0000313|EMBL:ACZ91618.1, ECO:0000313|Proteomes:UP000002029};
RN   [1] {ECO:0000313|EMBL:ACZ91618.1, ECO:0000313|Proteomes:UP000002029}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 12428 / DSM 43021 / JCM 3005 / NI 9100
RC   {ECO:0000313|Proteomes:UP000002029};
RX   PubMed=21304675; DOI=10.4056/sigs.631049;
RA   Nolan M., Sikorski J., Jando M., Lucas S., Lapidus A.,
RA   Glavina Del Rio T., Chen F., Tice H., Pitluck S., Cheng J.F.,
RA   Chertkov O., Sims D., Meincke L., Brettin T., Han C., Detter J.C.,
RA   Bruce D., Goodwin L., Land M., Hauser L., Chang Y.J., Jeffries C.D.,
RA   Ivanova N., Mavromatis K., Mikhailova N., Chen A., Palaniappan K.,
RA   Chain P., Rohde M., Goker M., Bristow J., Eisen J.A., Markowitz V.,
RA   Hugenholtz P., Kyrpides N.C., Klenk H.P.;
RT   "Complete genome sequence of Streptosporangium roseum type strain (NI
RT   9100).";
RL   Stand. Genomic Sci. 2:29-37(2010).
CC   -!- SIMILARITY: Belongs to the major facilitator superfamily.
CC       {ECO:0000256|SAAS:SAAS00769108}.
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DR   EMBL; CP001814; ACZ91618.1; -; Genomic_DNA.
DR   STRING; 479432.Sros_8987; -.
DR   EnsemblBacteria; ACZ91618; ACZ91618; Sros_8987.
DR   KEGG; sro:Sros_8987; -.
DR   eggNOG; ENOG4105C0R; Bacteria.
DR   eggNOG; ENOG410XNN3; LUCA.
DR   HOGENOM; HOG000239124; -.
DR   OMA; MTYLDNN; -.
DR   BioCyc; SROS479432:G1GGL-8771-MONOMER; -.
DR   Proteomes; UP000002029; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR   GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR   CDD; cd06174; MFS; 1.
DR   InterPro; IPR004638; EmrB-like.
DR   InterPro; IPR011701; MFS.
DR   InterPro; IPR020846; MFS_dom.
DR   InterPro; IPR036259; MFS_trans_sf.
DR   InterPro; IPR005829; Sugar_transporter_CS.
DR   Pfam; PF07690; MFS_1; 1.
DR   SUPFAM; SSF103473; SSF103473; 1.
DR   TIGRFAMs; TIGR00711; efflux_EmrB; 1.
DR   PROSITE; PS50850; MFS; 1.
DR   PROSITE; PS00216; SUGAR_TRANSPORT_1; 1.
PE   3: Inferred from homology;
DR   PRODOM; D2B973.
DR   SWISS-2DPAGE; D2B973.
KW   Cell membrane {ECO:0000256|SAAS:SAAS00769078};
KW   Complete proteome {ECO:0000313|Proteomes:UP000002029};
KW   Membrane {ECO:0000256|SAAS:SAAS00769060, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000002029};
KW   Transmembrane {ECO:0000256|SAAS:SAAS00769091,
KW   ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAAS:SAAS00769070,
KW   ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|SAAS:SAAS00769034}.
FT   TRANSMEM      7     24       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM     44     63       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM     75     94       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    100    122       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    134    156       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    162    184       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    196    216       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    228    245       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    266    288       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    300    318       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    330    349       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    361    384       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    396    414       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    434    457       Helical. {ECO:0000256|SAM:Phobius}.
FT   DOMAIN        9    461       MFS. {ECO:0000259|PROSITE:PS50850}.
SQ   SEQUENCE   478 AA;  49594 MW;  E19303F8CF9A7245 CRC64;
     MTATRKWWAL GAISLATFMT YLDNNVVNVA LPTIQRDLGV SISGLEWIVS GYILVFAGLM
     LVGGRLADVF GRRRIFMIGL GVFTVASLAA GLATDGTGLI AARALQGVGA AFLTPTALAL
     LTSIFPDPRE RATAVGMWSA VGALALALGP LTGGFISERW DWGWIYLINV PIGIATFGLG
     LWAIRVAPQD RVRHSLDVPG LVTSGLALSA LTYGLIEGDG AGWTSPEILG AFGLAVAAAV
     TFVVIETRSR EPMIDLSLFR SRVFSGGVLS MGLWSFGVFG IYFFTALYLQ NALGFSPMEA
     GVSFVPMALV MAVTAAVASR ISGALGTART VAAGLLLMAA AVFGLSFIGE GASFGELLPW
     FLVYGLGGGL LVPLTTAILG TLPAGRAGVA SGVLNVSREI FGLLGITVLG AILTGRQTSI
     LRDGATPLTA FLEAYQSTLV IAAAIVLVGV PVSLFALRIP RTPEHVEAPA ERPAVPVA
//

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