(data stored in SCRATCH zone)

SWISSPROT: D3F553_CONWI

ID   D3F553_CONWI            Unreviewed;       426 AA.
AC   D3F553;
DT   23-MAR-2010, integrated into UniProtKB/TrEMBL.
DT   23-MAR-2010, sequence version 1.
DT   30-AUG-2017, entry version 45.
DE   SubName: Full=Acetyl-CoA acetyltransferase {ECO:0000313|EMBL:ADB48631.1};
DE            EC=2.3.1.16 {ECO:0000313|EMBL:ADB48631.1};
GN   OrderedLocusNames=Cwoe_0195 {ECO:0000313|EMBL:ADB48631.1};
OS   Conexibacter woesei (strain DSM 14684 / JCM 11494 / NBRC 100937 /
OS   ID131577).
OC   Bacteria; Actinobacteria; Thermoleophilia; Solirubrobacterales;
OC   Conexibacteraceae; Conexibacter.
OX   NCBI_TaxID=469383 {ECO:0000313|EMBL:ADB48631.1, ECO:0000313|Proteomes:UP000008229};
RN   [1] {ECO:0000313|Proteomes:UP000008229}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 14684 / JCM 11494 / NBRC 100937 / ID131577
RC   {ECO:0000313|Proteomes:UP000008229};
RG   US DOE Joint Genome Institute (JGI-PGF);
RA   Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E.,
RA   Tice H., Bruce D., Goodwin L., Pitluck S., Kyrpides N., Mavromatis K.,
RA   Ivanova N., Mikhailova N., Chertkov O., Brettin T., Detter J.C.,
RA   Han C., Larimer F., Land M., Hauser L., Markowitz V., Cheng J.-F.,
RA   Hugenholtz P., Woyke T., Wu D., Pukall R., Steenblock K.,
RA   Schneider S., Klenk H.-P., Eisen J.A.;
RT   "The complete genome of Conexibacter woesei DSM 14684.";
RL   Submitted (JAN-2010) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the thiolase family.
CC       {ECO:0000256|RuleBase:RU003557}.
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DR   EMBL; CP001854; ADB48631.1; -; Genomic_DNA.
DR   RefSeq; WP_012931684.1; NC_013739.1.
DR   ProteinModelPortal; D3F553; -.
DR   STRING; 469383.Cwoe_0195; -.
DR   EnsemblBacteria; ADB48631; ADB48631; Cwoe_0195.
DR   KEGG; cwo:Cwoe_0195; -.
DR   eggNOG; ENOG4105CHU; Bacteria.
DR   eggNOG; COG0183; LUCA.
DR   HOGENOM; HOG000012240; -.
DR   KO; K00626; -.
DR   OMA; AWESEDY; -.
DR   OrthoDB; POG091H065K; -.
DR   BioCyc; CWOE469383:GH82-195-MONOMER; -.
DR   Proteomes; UP000008229; Chromosome.
DR   GO; GO:0003988; F:acetyl-CoA C-acyltransferase activity; IEA:UniProtKB-EC.
DR   GO; GO:0008152; P:metabolic process; IEA:InterPro.
DR   CDD; cd00751; thiolase; 1.
DR   Gene3D; 3.40.47.10; -; 2.
DR   InterPro; IPR002155; Thiolase.
DR   InterPro; IPR016039; Thiolase-like.
DR   InterPro; IPR020617; Thiolase_C.
DR   InterPro; IPR020616; Thiolase_N.
DR   Pfam; PF02803; Thiolase_C; 1.
DR   Pfam; PF00108; Thiolase_N; 1.
DR   PIRSF; PIRSF000429; Ac-CoA_Ac_transf; 1.
DR   SUPFAM; SSF53901; SSF53901; 2.
DR   TIGRFAMs; TIGR01930; AcCoA-C-Actrans; 1.
PE   3: Inferred from homology;
DR   PRODOM; D3F553.
DR   SWISS-2DPAGE; D3F553.
KW   Acyltransferase {ECO:0000256|RuleBase:RU003557,
KW   ECO:0000313|EMBL:ADB48631.1};
KW   Complete proteome {ECO:0000313|Proteomes:UP000008229};
KW   Reference proteome {ECO:0000313|Proteomes:UP000008229};
KW   Transferase {ECO:0000256|RuleBase:RU003557,
KW   ECO:0000313|EMBL:ADB48631.1}.
FT   DOMAIN        9    275       Thiolase_N. {ECO:0000259|Pfam:PF00108}.
FT   DOMAIN      284    425       Thiolase_C. {ECO:0000259|Pfam:PF02803}.
FT   ACT_SITE     93     93       Acyl-thioester intermediate.
FT                                {ECO:0000256|PIRSR:PIRSR000429-1}.
FT   ACT_SITE    383    383       Proton acceptor. {ECO:0000256|PIRSR:
FT                                PIRSR000429-1}.
FT   ACT_SITE    413    413       Proton acceptor. {ECO:0000256|PIRSR:
FT                                PIRSR000429-1}.
SQ   SEQUENCE   426 AA;  45242 MW;  13560E5FE1530B1B CRC64;
     MTADGPRRVA VLGGNRIPFA RSNSVYSKAS NQDMLTAALD GLVSRYGLEG ERLGEVVAGA
     VLKHSRDFNL TRECVLGSRL APETPAYDIQ QACGTGLEAA ILVANKIRLG QIESGVAGGT
     DTTSDAPLAV NEDLREILLD ANRKKSTQDK LKTLLRLRPQ HLAPAIPRNE EPRTGLSMGE
     HQARTAAEWG ITREAQDALA VRSHKNLAAA YERGFQDDLV TPYLGLERDQ NLRPDSNVEK
     AAKLKPVFGG KDGTMTAANS TPLSDGAAVA LLGSEAWAQE HELTPLAYFV DGEAAAVDYV
     HGKEGLLMAP AYAVPRMLAR NGLTLQEFDL YEIHEAFASQ VLSTLKAWED PAFCTQRLGL
     DRPLGAIDRD KLNVNGSSLA AGHPFAATGG RIVAGLAKAL HERGGGRGLI SVCAAGGQGV
     VAILEA
//

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