(data stored in ACNUC1104 zone)

SWISSPROT: D3F5P3_CONWI

ID   D3F5P3_CONWI            Unreviewed;       522 AA.
AC   D3F5P3;
DT   23-MAR-2010, integrated into UniProtKB/TrEMBL.
DT   23-MAR-2010, sequence version 1.
DT   10-APR-2019, entry version 46.
DE   SubName: Full=Drug resistance transporter, EmrB/QacA subfamily {ECO:0000313|EMBL:ADB52592.1};
GN   OrderedLocusNames=Cwoe_4177 {ECO:0000313|EMBL:ADB52592.1};
OS   Conexibacter woesei (strain DSM 14684 / JCM 11494 / NBRC 100937 /
OS   ID131577).
OC   Bacteria; Actinobacteria; Thermoleophilia; Solirubrobacterales;
OC   Conexibacteraceae; Conexibacter.
OX   NCBI_TaxID=469383 {ECO:0000313|EMBL:ADB52592.1, ECO:0000313|Proteomes:UP000008229};
RN   [1] {ECO:0000313|EMBL:ADB52592.1, ECO:0000313|Proteomes:UP000008229}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 14684 / JCM 11494 / NBRC 100937 / ID131577
RC   {ECO:0000313|Proteomes:UP000008229};
RX   PubMed=21304704;
RA   Pukall R., Lapidus A., Glavina Del Rio T., Copeland A., Tice H.,
RA   Cheng J.-F., Lucas S., Chen F., Nolan M., Bruce D., Goodwin L.,
RA   Pitluck S., Mavromatis K., Ivanova N., Ovchinnikova G., Pati A.,
RA   Chen A., Palaniappan K., Land M., Hauser L., Chang Y.-J.,
RA   Jeffries C.D., Chain P., Meincke L., Sims D., Brettin T., Detter J.C.,
RA   Rohde M., Goeker M., Bristow J., Eisen J.A., Markowitz V.,
RA   Kyrpides N.C., Klenk H.-P., Hugenholtz P.;
RT   "Complete genome sequence of Conexibacter woesei type strain
RT   (ID131577).";
RL   Stand. Genomic Sci. 2:212-219(2010).
RN   [2] {ECO:0000313|Proteomes:UP000008229}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 14684 / JCM 11494 / NBRC 100937 / ID131577
RC   {ECO:0000313|Proteomes:UP000008229};
RG   US DOE Joint Genome Institute (JGI-PGF);
RA   Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E.,
RA   Tice H., Bruce D., Goodwin L., Pitluck S., Kyrpides N., Mavromatis K.,
RA   Ivanova N., Mikhailova N., Chertkov O., Brettin T., Detter J.C.,
RA   Han C., Larimer F., Land M., Hauser L., Markowitz V., Cheng J.-F.,
RA   Hugenholtz P., Woyke T., Wu D., Pukall R., Steenblock K.,
RA   Schneider S., Klenk H.-P., Eisen J.A.;
RT   "The complete genome of Conexibacter woesei DSM 14684.";
RL   Submitted (JAN-2010) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the major facilitator superfamily.
CC       {ECO:0000256|SAAS:SAAS00769108}.
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DR   EMBL; CP001854; ADB52592.1; -; Genomic_DNA.
DR   RefSeq; WP_012935643.1; NC_013739.1.
DR   STRING; 469383.Cwoe_4177; -.
DR   EnsemblBacteria; ADB52592; ADB52592; Cwoe_4177.
DR   KEGG; cwo:Cwoe_4177; -.
DR   eggNOG; ENOG4105C57; Bacteria.
DR   eggNOG; COG0477; LUCA.
DR   HOGENOM; HOG000239124; -.
DR   OrthoDB; 1108236at2; -.
DR   BioCyc; CWOE469383:G1GH5-4175-MONOMER; -.
DR   Proteomes; UP000008229; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR   GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR   CDD; cd06174; MFS; 1.
DR   InterPro; IPR004638; EmrB-like.
DR   InterPro; IPR011701; MFS.
DR   InterPro; IPR020846; MFS_dom.
DR   InterPro; IPR036259; MFS_trans_sf.
DR   Pfam; PF07690; MFS_1; 1.
DR   SUPFAM; SSF103473; SSF103473; 2.
DR   TIGRFAMs; TIGR00711; efflux_EmrB; 1.
DR   PROSITE; PS50850; MFS; 1.
PE   3: Inferred from homology;
DR   PRODOM; D3F5P3.
DR   SWISS-2DPAGE; D3F5P3.
KW   Cell membrane {ECO:0000256|SAAS:SAAS00769078};
KW   Complete proteome {ECO:0000313|Proteomes:UP000008229};
KW   Membrane {ECO:0000256|SAAS:SAAS00769060, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000008229};
KW   Transmembrane {ECO:0000256|SAAS:SAAS00769091,
KW   ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAAS:SAAS00769070,
KW   ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|SAAS:SAAS00769034}.
FT   TRANSMEM     20     41       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM     53     73       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM     85    104       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    110    131       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    143    165       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    171    193       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    205    225       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    237    258       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    279    297       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    309    327       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    339    359       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    365    388       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    409    429       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    471    498       Helical. {ECO:0000256|SAM:Phobius}.
FT   DOMAIN       19    502       MFS. {ECO:0000259|PROSITE:PS50850}.
SQ   SEQUENCE   522 AA;  54135 MW;  834007EDDFB7D3D2 CRC64;
     MTDRIRALSL TEENRRWWTL GAMCFALFML MLDNTVVNVA LPSIQSDLNA DLASLEWTIN
     AYTLSLAVLL VVGGRLGDIF GRRKIFLIGV SVFALSSAAI GLAPSDTALI VGRAIQGIGA
     AMMMPATLSI VTNAFPPHER GKALGTWAGV SALALAIGPV VGGFLTEQVS WRAIFFLNLP
     VAAAAIAMTL FSTRESRDET VGRQLDYAGI ATLTIGLTGL VLGLIEGNAW GWGSARIVGL
     FALAVVSLAA FVVVELRVRT PMVDFGVFRS RQFAGASSVG FIVSFGMMAM FFFTALYMQN
     ILGFSALEAG VRFLPTTLVL IVMGPLAGRL TDRIGPKPLL VSGMLITGAS QIWQSFLTAD
     TGYSFLLPSF VLMGIGMGLV MSPMTTAAMN SVDRTKAGVA SGVLSMGRMV GSSLGVAIFG
     AVVASVGSAK LEQSLPGLPA GARDRLSESL GGGGVSDGAA PARIVDATHD AFISAFGTGM
     KISGIVAIFG AFVALALIRG GRPAAPATVP AEAEAEAELA PA
//

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