(data stored in SCRATCH zone)

SWISSPROT: D3UYB6_XENBS

ID   D3UYB6_XENBS            Unreviewed;       191 AA.
AC   D3UYB6;
DT   20-APR-2010, integrated into UniProtKB/TrEMBL.
DT   20-APR-2010, sequence version 1.
DT   08-MAY-2019, entry version 53.
DE   RecName: Full=Fe/S biogenesis protein NfuA {ECO:0000256|HAMAP-Rule:MF_01637, ECO:0000256|SAAS:SAAS01079107};
GN   Name=nfuA {ECO:0000256|HAMAP-Rule:MF_01637,
GN   ECO:0000313|EMBL:CBJ79294.1};
GN   OrderedLocusNames=XBJ1_0143 {ECO:0000313|EMBL:CBJ79294.1};
OS   Xenorhabdus bovienii (strain SS-2004).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Morganellaceae; Xenorhabdus.
OX   NCBI_TaxID=406818 {ECO:0000313|EMBL:CBJ79294.1, ECO:0000313|Proteomes:UP000002045};
RN   [1] {ECO:0000313|Proteomes:UP000002045}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=SS-2004 {ECO:0000313|Proteomes:UP000002045};
RA   Goodrich-Blair H., Barbazuk B., Bode H.B., Darby C., Du Z., Forst S.,
RA   Gaudriault S., Goldman B.S., Goodner B., Henkhaus J., Latreille P.,
RA   Medigue C., Miller N., Norton S., Ogier J.C., Rouy Z., Slater S.,
RA   Suen G.;
RT   "Complete genome sequence of Xenorhabdus nematophila (strain ATCC
RT   19061 / DSM 3370 / LMG 1036 / NCIB 9965 / AN6).";
RL   Submitted (FEB-2010) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EMBL:CBJ79294.1, ECO:0000313|Proteomes:UP000002045}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=SS-2004 {ECO:0000313|EMBL:CBJ79294.1,
RC   ECO:0000313|Proteomes:UP000002045};
RX   PubMed=22125637; DOI=10.1371/journal.pone.0027909;
RA   Chaston J.M., Suen G., Tucker S.L., Andersen A.W., Bhasin A., Bode E.,
RA   Bode H.B., Brachmann A.O., Cowles C.E., Cowles K.N., Darby C.,
RA   de Leon L., Drace K., Du Z., Givaudan A., Herbert Tran E.E.,
RA   Jewell K.A., Knack J.J., Krasomil-Osterfeld K.C., Kukor R., Lanois A.,
RA   Latreille P., Leimgruber N.K., Lipke C.M., Liu R., Lu X.,
RA   Martens E.C., Marri P.R., Medigue C., Menard M.L., Miller N.M.,
RA   Morales-Soto N., Norton S., Ogier J.C., Orchard S.S., Park D.,
RA   Park Y., Qurollo B.A., Sugar D.R., Richards G.R., Rouy Z.,
RA   Slominski B., Slominski K., Snyder H., Tjaden B.C., van der Hoeven R.,
RA   Welch R.D., Wheeler C., Xiang B., Barbazuk B., Gaudriault S.,
RA   Goodner B., Slater S.C., Forst S., Goldman B.S., Goodrich-Blair H.;
RT   "The entomopathogenic bacterial endosymbionts xenorhabdus and
RT   photorhabdus: convergent lifestyles from divergent genomes.";
RL   PLoS ONE 6:e27909-e27909(2011).
CC   -!- FUNCTION: Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-
CC       4S cluster, can transfer this cluster to apoproteins, and thereby
CC       intervenes in the maturation of Fe/S proteins. Could also act as a
CC       scaffold/chaperone for damaged Fe/S proteins. {ECO:0000256|HAMAP-
CC       Rule:MF_01637, ECO:0000256|SAAS:SAAS01079114}.
CC   -!- COFACTOR:
CC       Name=[4Fe-4S] cluster; Xref=ChEBI:CHEBI:49883;
CC         Evidence={ECO:0000256|HAMAP-Rule:MF_01637};
CC       Note=Binds 1 [4Fe-4S] cluster per subunit. The cluster is
CC       presumably bound at the interface of two monomers.
CC       {ECO:0000256|HAMAP-Rule:MF_01637};
CC   -!- SUBUNIT: Homodimer. {ECO:0000256|HAMAP-Rule:MF_01637,
CC       ECO:0000256|SAAS:SAAS01079105}.
CC   -!- SIMILARITY: Belongs to the NfuA family. {ECO:0000256|HAMAP-
CC       Rule:MF_01637, ECO:0000256|SAAS:SAAS01079102}.
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DR   EMBL; FN667741; CBJ79294.1; -; Genomic_DNA.
DR   RefSeq; WP_012986761.1; NC_013892.1.
DR   STRING; 406818.XBJ1_0143; -.
DR   EnsemblBacteria; CBJ79294; CBJ79294; XBJ1_0143.
DR   GeneID; 8829767; -.
DR   KEGG; xbo:XBJ1_0143; -.
DR   eggNOG; ENOG4107RUK; Bacteria.
DR   eggNOG; COG0316; LUCA.
DR   eggNOG; COG0694; LUCA.
DR   HOGENOM; HOG000137052; -.
DR   KO; K07400; -.
DR   OMA; ETCLAYC; -.
DR   BioCyc; XBOV406818:XBJ1_RS00635-MONOMER; -.
DR   Proteomes; UP000002045; Chromosome.
DR   GO; GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0005506; F:iron ion binding; IEA:InterPro.
DR   GO; GO:0016226; P:iron-sulfur cluster assembly; IEA:UniProtKB-UniRule.
DR   GO; GO:0051604; P:protein maturation; IEA:UniProtKB-UniRule.
DR   Gene3D; 2.60.300.12; -; 1.
DR   Gene3D; 3.30.300.130; -; 1.
DR   HAMAP; MF_01637; Fe_S_biogen_NfuA; 1.
DR   InterPro; IPR017726; Fe/S_biogenesis_protein_NfuA.
DR   InterPro; IPR000361; FeS_biogenesis.
DR   InterPro; IPR034904; FSCA_dom_sf.
DR   InterPro; IPR035903; HesB-like_dom_sf.
DR   InterPro; IPR001075; NIF_FeS_clus_asmbl_NifU_C.
DR   Pfam; PF01521; Fe-S_biosyn; 1.
DR   Pfam; PF01106; NifU; 1.
DR   ProDom; PD002830; NIF_FeS_clus_asmbl_NifU_C; 1.
DR   SUPFAM; SSF117916; SSF117916; 1.
DR   SUPFAM; SSF89360; SSF89360; 1.
DR   TIGRFAMs; TIGR03341; YhgI_GntY; 1.
PE   3: Inferred from homology;
DR   PRODOM; D3UYB6.
DR   SWISS-2DPAGE; D3UYB6.
KW   4Fe-4S {ECO:0000256|HAMAP-Rule:MF_01637,
KW   ECO:0000256|SAAS:SAAS01079112};
KW   Complete proteome {ECO:0000313|Proteomes:UP000002045};
KW   Iron {ECO:0000256|HAMAP-Rule:MF_01637, ECO:0000256|SAAS:SAAS01079349};
KW   Iron-sulfur {ECO:0000256|HAMAP-Rule:MF_01637,
KW   ECO:0000256|SAAS:SAAS01079115};
KW   Metal-binding {ECO:0000256|HAMAP-Rule:MF_01637,
KW   ECO:0000256|SAAS:SAAS01079329};
KW   Reference proteome {ECO:0000313|Proteomes:UP000002045}.
FT   DOMAIN        2     99       Fe-S_biosyn. {ECO:0000259|Pfam:PF01521}.
FT   DOMAIN      111    177       NifU. {ECO:0000259|Pfam:PF01106}.
FT   METAL       149    149       Iron-sulfur (4Fe-4S). {ECO:0000256|HAMAP-
FT                                Rule:MF_01637}.
FT   METAL       152    152       Iron-sulfur (4Fe-4S). {ECO:0000256|HAMAP-
FT                                Rule:MF_01637}.
SQ   SEQUENCE   191 AA;  20806 MW;  062426D8F29CD298 CRC64;
     MINITEAAQA HFAKLLASQE PGTQIRVFVI NPGTPTAECG VSYCPPDAVE ATDTELKFDQ
     ISAYVDEISA PFLAEAVIDF VTDQLGSQLT LKAPNAKMRK VTDDAPLIER VEYVLQSQIN
     PQLAGHGGRV SLMEITDAGY AILQFGGGCN GCSMVDVTLK EGIEKELLNM FPELKGVRDL
     TEHQRGEHSY Y
//

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