(data stored in SCRATCH zone)

SWISSPROT: D3UYK4_XENBS

ID   D3UYK4_XENBS            Unreviewed;       693 AA.
AC   D3UYK4;
DT   20-APR-2010, integrated into UniProtKB/TrEMBL.
DT   20-APR-2010, sequence version 1.
DT   08-MAY-2019, entry version 57.
DE   RecName: Full=ATP-dependent DNA helicase RecG {ECO:0000256|RuleBase:RU363016};
DE            EC=3.6.4.12 {ECO:0000256|RuleBase:RU363016};
GN   Name=recG {ECO:0000256|RuleBase:RU363016,
GN   ECO:0000313|EMBL:CBJ79382.1};
GN   OrderedLocusNames=XBJ1_0231 {ECO:0000313|EMBL:CBJ79382.1};
OS   Xenorhabdus bovienii (strain SS-2004).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Morganellaceae; Xenorhabdus.
OX   NCBI_TaxID=406818 {ECO:0000313|EMBL:CBJ79382.1, ECO:0000313|Proteomes:UP000002045};
RN   [1] {ECO:0000313|Proteomes:UP000002045}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=SS-2004 {ECO:0000313|Proteomes:UP000002045};
RA   Goodrich-Blair H., Barbazuk B., Bode H.B., Darby C., Du Z., Forst S.,
RA   Gaudriault S., Goldman B.S., Goodner B., Henkhaus J., Latreille P.,
RA   Medigue C., Miller N., Norton S., Ogier J.C., Rouy Z., Slater S.,
RA   Suen G.;
RT   "Complete genome sequence of Xenorhabdus nematophila (strain ATCC
RT   19061 / DSM 3370 / LMG 1036 / NCIB 9965 / AN6).";
RL   Submitted (FEB-2010) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EMBL:CBJ79382.1, ECO:0000313|Proteomes:UP000002045}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=SS-2004 {ECO:0000313|EMBL:CBJ79382.1,
RC   ECO:0000313|Proteomes:UP000002045};
RX   PubMed=22125637; DOI=10.1371/journal.pone.0027909;
RA   Chaston J.M., Suen G., Tucker S.L., Andersen A.W., Bhasin A., Bode E.,
RA   Bode H.B., Brachmann A.O., Cowles C.E., Cowles K.N., Darby C.,
RA   de Leon L., Drace K., Du Z., Givaudan A., Herbert Tran E.E.,
RA   Jewell K.A., Knack J.J., Krasomil-Osterfeld K.C., Kukor R., Lanois A.,
RA   Latreille P., Leimgruber N.K., Lipke C.M., Liu R., Lu X.,
RA   Martens E.C., Marri P.R., Medigue C., Menard M.L., Miller N.M.,
RA   Morales-Soto N., Norton S., Ogier J.C., Orchard S.S., Park D.,
RA   Park Y., Qurollo B.A., Sugar D.R., Richards G.R., Rouy Z.,
RA   Slominski B., Slominski K., Snyder H., Tjaden B.C., van der Hoeven R.,
RA   Welch R.D., Wheeler C., Xiang B., Barbazuk B., Gaudriault S.,
RA   Goodner B., Slater S.C., Forst S., Goldman B.S., Goodrich-Blair H.;
RT   "The entomopathogenic bacterial endosymbionts xenorhabdus and
RT   photorhabdus: convergent lifestyles from divergent genomes.";
RL   PLoS ONE 6:e27909-e27909(2011).
CC   -!- FUNCTION: Critical role in recombination and DNA repair. Helps
CC       process Holliday junction intermediates to mature products by
CC       catalyzing branch migration. Has a DNA unwinding activity
CC       characteristic of a DNA helicase with a 3'- to 5'- polarity.
CC       Unwinds branched duplex DNA (Y-DNA).
CC       {ECO:0000256|RuleBase:RU363016}.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC         ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC         ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=3.6.4.12;
CC         Evidence={ECO:0000256|RuleBase:RU363016};
CC   -!- SIMILARITY: Belongs to the helicase family. RecG subfamily.
CC       {ECO:0000256|RuleBase:RU363016}.
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DR   EMBL; FN667741; CBJ79382.1; -; Genomic_DNA.
DR   RefSeq; WP_012986845.1; NC_013892.1.
DR   STRING; 406818.XBJ1_0231; -.
DR   EnsemblBacteria; CBJ79382; CBJ79382; XBJ1_0231.
DR   GeneID; 8829854; -.
DR   KEGG; xbo:XBJ1_0231; -.
DR   PATRIC; fig|406818.4.peg.212; -.
DR   eggNOG; ENOG4105CB5; Bacteria.
DR   eggNOG; COG1200; LUCA.
DR   HOGENOM; HOG000036617; -.
DR   KO; K03655; -.
DR   OMA; RETNDGF; -.
DR   BioCyc; XBOV406818:XBJ1_RS01005-MONOMER; -.
DR   Proteomes; UP000002045; Chromosome.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004003; F:ATP-dependent DNA helicase activity; IEA:InterPro.
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   GO; GO:0006310; P:DNA recombination; IEA:UniProtKB-UniRule.
DR   GO; GO:0006281; P:DNA repair; IEA:UniProtKB-UniRule.
DR   CDD; cd00079; HELICc; 1.
DR   InterPro; IPR004609; ATP-dep_DNA_helicase_RecG.
DR   InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR   InterPro; IPR014001; Helicase_ATP-bd.
DR   InterPro; IPR001650; Helicase_C.
DR   InterPro; IPR012340; NA-bd_OB-fold.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR033454; RecG_wedge.
DR   Pfam; PF00270; DEAD; 1.
DR   Pfam; PF00271; Helicase_C; 1.
DR   Pfam; PF17191; RecG_wedge; 1.
DR   SMART; SM00487; DEXDc; 1.
DR   SMART; SM00490; HELICc; 1.
DR   SUPFAM; SSF50249; SSF50249; 1.
DR   SUPFAM; SSF52540; SSF52540; 2.
DR   TIGRFAMs; TIGR00643; recG; 1.
DR   PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR   PROSITE; PS51194; HELICASE_CTER; 1.
PE   3: Inferred from homology;
DR   PRODOM; D3UYK4.
DR   SWISS-2DPAGE; D3UYK4.
KW   ATP-binding {ECO:0000256|RuleBase:RU363016};
KW   Complete proteome {ECO:0000313|Proteomes:UP000002045};
KW   DNA damage {ECO:0000256|RuleBase:RU363016};
KW   DNA recombination {ECO:0000256|RuleBase:RU363016};
KW   DNA repair {ECO:0000256|RuleBase:RU363016};
KW   Helicase {ECO:0000256|RuleBase:RU363016, ECO:0000313|EMBL:CBJ79382.1};
KW   Hydrolase {ECO:0000256|RuleBase:RU363016,
KW   ECO:0000313|EMBL:CBJ79382.1};
KW   Nucleotide-binding {ECO:0000256|RuleBase:RU363016};
KW   Reference proteome {ECO:0000313|Proteomes:UP000002045}.
FT   DOMAIN      283    448       Helicase ATP-binding.
FT                                {ECO:0000259|PROSITE:PS51192}.
FT   DOMAIN      482    628       Helicase C-terminal.
FT                                {ECO:0000259|PROSITE:PS51194}.
SQ   SEQUENCE   693 AA;  77283 MW;  9EAD585F88E2130F CRC64;
     MKGRLLDAIP LTTLRGVGAS QVTKLAKLGL VNLQDLLLHL PLRYEDQTRL YSINDLLPGV
     YATVTGEVLR THVTFGRRRI MTCQISDGTG VLTLRFFNFT AAMKNNLAEG KHVIAYGEIR
     RGNQGPEIIH PEYKTQQHAE RIQLQDTLTP IYPTTEGVRQ TTLRKLIEQA LELLDTCVIN
     ELLPEEFSRK LISLPNALHT LHRPPPDVSL TDLDNRRHPA QRRLILEELL AHHLSMLAVR
     AGAQRFHAQQ LTADNSLKQQ LISQLPFVPT GAQVRVVAEI EQDLEKNVPM MRLIQGDVGS
     GKTLVAALAA LRALVHGKQV ALMAPTELLA EQHANTFRQW FEPLGIQVGW LAGKQKGKAR
     QAQQEAIANG QVSMVVGTHA MFQEQVRFSG LALVIIDEQH RFGVHQRLAL WEKGCEQGFH
     PHQLIMTATP IPRTLAMTAY ADLDTSIIDE LPPGRTPVTT VAIPDTRRNE IIQRIKSACL
     DEGRQAYWVC TLIEDSEVLE AQAAQATSEE LALILPDLKI GLVHGRMKPA EKQTIMDAFK
     RGELQLLVAT TVIEVGVDVP NASLMIIDNP ERLGLAQLHQ LRGRVGRGAV ASHCVLLYKT
     PLTNTAKIRL QVLRDSNDGF VIAQKDLEIR GPGELLGTRQ TGNAEFRIAD LLRDQGMLSE
     VQRISSYIHQ HYPEHAKALI ERWLPDRSQY SHA
//

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