(data stored in SCRATCH zone)

SWISSPROT: D3UZB1_XENBS

ID   D3UZB1_XENBS            Unreviewed;       762 AA.
AC   D3UZB1;
DT   20-APR-2010, integrated into UniProtKB/TrEMBL.
DT   20-APR-2010, sequence version 1.
DT   08-MAY-2019, entry version 63.
DE   SubName: Full=Pb/Cd/Zn/Hg transporting ATPase (P-type ATPase family) {ECO:0000313|EMBL:CBJ79693.1};
DE            EC=3.6.1.- {ECO:0000313|EMBL:CBJ79693.1};
GN   Name=zntA {ECO:0000313|EMBL:CBJ79693.1};
GN   OrderedLocusNames=XBJ1_0549 {ECO:0000313|EMBL:CBJ79693.1};
OS   Xenorhabdus bovienii (strain SS-2004).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Morganellaceae; Xenorhabdus.
OX   NCBI_TaxID=406818 {ECO:0000313|EMBL:CBJ79693.1, ECO:0000313|Proteomes:UP000002045};
RN   [1] {ECO:0000313|Proteomes:UP000002045}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=SS-2004 {ECO:0000313|Proteomes:UP000002045};
RA   Goodrich-Blair H., Barbazuk B., Bode H.B., Darby C., Du Z., Forst S.,
RA   Gaudriault S., Goldman B.S., Goodner B., Henkhaus J., Latreille P.,
RA   Medigue C., Miller N., Norton S., Ogier J.C., Rouy Z., Slater S.,
RA   Suen G.;
RT   "Complete genome sequence of Xenorhabdus nematophila (strain ATCC
RT   19061 / DSM 3370 / LMG 1036 / NCIB 9965 / AN6).";
RL   Submitted (FEB-2010) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EMBL:CBJ79693.1, ECO:0000313|Proteomes:UP000002045}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=SS-2004 {ECO:0000313|EMBL:CBJ79693.1,
RC   ECO:0000313|Proteomes:UP000002045};
RX   PubMed=22125637; DOI=10.1371/journal.pone.0027909;
RA   Chaston J.M., Suen G., Tucker S.L., Andersen A.W., Bhasin A., Bode E.,
RA   Bode H.B., Brachmann A.O., Cowles C.E., Cowles K.N., Darby C.,
RA   de Leon L., Drace K., Du Z., Givaudan A., Herbert Tran E.E.,
RA   Jewell K.A., Knack J.J., Krasomil-Osterfeld K.C., Kukor R., Lanois A.,
RA   Latreille P., Leimgruber N.K., Lipke C.M., Liu R., Lu X.,
RA   Martens E.C., Marri P.R., Medigue C., Menard M.L., Miller N.M.,
RA   Morales-Soto N., Norton S., Ogier J.C., Orchard S.S., Park D.,
RA   Park Y., Qurollo B.A., Sugar D.R., Richards G.R., Rouy Z.,
RA   Slominski B., Slominski K., Snyder H., Tjaden B.C., van der Hoeven R.,
RA   Welch R.D., Wheeler C., Xiang B., Barbazuk B., Gaudriault S.,
RA   Goodner B., Slater S.C., Forst S., Goldman B.S., Goodrich-Blair H.;
RT   "The entomopathogenic bacterial endosymbionts xenorhabdus and
RT   photorhabdus: convergent lifestyles from divergent genomes.";
RL   PLoS ONE 6:e27909-e27909(2011).
CC   -!- SUBCELLULAR LOCATION: Cell membrane
CC       {ECO:0000256|RuleBase:RU362081}.
CC   -!- SIMILARITY: Belongs to the cation transport ATPase (P-type)
CC       (TC 3.A.3) family. Type IB subfamily.
CC       {ECO:0000256|RuleBase:RU362081}.
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DR   EMBL; FN667741; CBJ79693.1; -; Genomic_DNA.
DR   RefSeq; WP_012987147.1; NC_013892.1.
DR   STRING; 406818.XBJ1_0549; -.
DR   EnsemblBacteria; CBJ79693; CBJ79693; XBJ1_0549.
DR   GeneID; 8830171; -.
DR   KEGG; xbo:XBJ1_0549; -.
DR   PATRIC; fig|406818.4.peg.502; -.
DR   eggNOG; ENOG4105C59; Bacteria.
DR   eggNOG; COG2217; LUCA.
DR   HOGENOM; HOG000250399; -.
DR   KO; K01534; -.
DR   OMA; WLPWIYK; -.
DR   BioCyc; XBOV406818:XBJ1_RS02375-MONOMER; -.
DR   Proteomes; UP000002045; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-UniRule.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0019829; F:cation-transporting ATPase activity; IEA:InterPro.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0030001; P:metal ion transport; IEA:InterPro.
DR   CDD; cd00371; HMA; 1.
DR   Gene3D; 3.40.1110.10; -; 1.
DR   Gene3D; 3.40.50.1000; -; 1.
DR   InterPro; IPR023299; ATPase_P-typ_cyto_dom_N.
DR   InterPro; IPR018303; ATPase_P-typ_P_site.
DR   InterPro; IPR023298; ATPase_P-typ_TM_dom_sf.
DR   InterPro; IPR008250; ATPase_P-typ_transduc_dom_A_sf.
DR   InterPro; IPR036412; HAD-like_sf.
DR   InterPro; IPR023214; HAD_sf.
DR   InterPro; IPR017969; Heavy-metal-associated_CS.
DR   InterPro; IPR006121; HMA_dom.
DR   InterPro; IPR036163; HMA_dom_sf.
DR   InterPro; IPR027256; P-typ_ATPase_IB.
DR   InterPro; IPR001757; P_typ_ATPase.
DR   Pfam; PF00403; HMA; 1.
DR   PRINTS; PR00120; HATPASE.
DR   SUPFAM; SSF55008; SSF55008; 1.
DR   SUPFAM; SSF56784; SSF56784; 1.
DR   SUPFAM; SSF81653; SSF81653; 1.
DR   SUPFAM; SSF81665; SSF81665; 1.
DR   TIGRFAMs; TIGR01525; ATPase-IB_hvy; 1.
DR   TIGRFAMs; TIGR01494; ATPase_P-type; 1.
DR   PROSITE; PS00154; ATPASE_E1_E2; 1.
DR   PROSITE; PS01047; HMA_1; 1.
DR   PROSITE; PS50846; HMA_2; 1.
PE   3: Inferred from homology;
DR   PRODOM; D3UZB1.
DR   SWISS-2DPAGE; D3UZB1.
KW   ATP-binding {ECO:0000256|RuleBase:RU362081};
KW   Complete proteome {ECO:0000313|Proteomes:UP000002045};
KW   Hydrolase {ECO:0000313|EMBL:CBJ79693.1};
KW   Membrane {ECO:0000256|RuleBase:RU362081};
KW   Metal-binding {ECO:0000256|PROSITE-ProRule:PRU00280,
KW   ECO:0000256|RuleBase:RU362081};
KW   Nucleotide-binding {ECO:0000256|RuleBase:RU362081};
KW   Reference proteome {ECO:0000313|Proteomes:UP000002045};
KW   Transmembrane {ECO:0000256|RuleBase:RU362081};
KW   Transmembrane helix {ECO:0000256|RuleBase:RU362081}.
FT   TRANSMEM    149    167       Helical. {ECO:0000256|RuleBase:RU362081}.
FT   TRANSMEM    173    190       Helical. {ECO:0000256|RuleBase:RU362081}.
FT   TRANSMEM    375    396       Helical. {ECO:0000256|RuleBase:RU362081}.
FT   TRANSMEM    402    426       Helical. {ECO:0000256|RuleBase:RU362081}.
FT   TRANSMEM    712    730       Helical. {ECO:0000256|RuleBase:RU362081}.
FT   DOMAIN       69    133       HMA. {ECO:0000259|PROSITE:PS50846}.
FT   METAL        79     79       {ECO:0000256|PROSITE-ProRule:PRU00280}.
FT   METAL        82     82       {ECO:0000256|PROSITE-ProRule:PRU00280}.
SQ   SEQUENCE   762 AA;  81396 MW;  66983D85E58BAF05 CRC64;
     MFSIFKKHKQ SQHGSLSHKN KDHKHSHGVH GKEDKSSHNA HEHDRGHCSH DHAPTIQDTT
     PLELTANQRF NWIIHGMDCP SCAGKIENAV KKLPEAKQVR VLFTTEKLVV DADSDIRAAV
     EQAVKQAGFE IKQTDSTIRL PPAANHWKTF SPILILIALM VISWGITKIN PPAGQIAFIV
     TTLIGLYPVA TKAIKLIRSG TPFAIETLMS VAAIGALFID ATAEAAMVIL LFKVGEVLES
     YAAGRARRGV SALMALVPEQ ALRVTGGEKK TVPAADLRPG DIIEIAPGAR LPTDAELLSP
     FASFDESALT GESIPVERQQ GEKVAAGCLS VDSAVQMRVF SEPGHNAIDR ILQLIEEAEE
     RRAPIERFID RFSRIYTPLI ILFSVLVVVI PPLLLAEPWE TWIYRGLTLL LIGCPCALVI
     STPAAITSAL AAATRRGALI KGGAALEQLG SVTTIALDKT GTLTEGKPRV TEIEPVENIS
     VETLLALAGA VESGSHHPLA KAILNAAENK GVTVVEAEHR KALAGIGVEG RLSGQKILVA
     APGRLPENTL STAWKQRVTE LESNGKTAVA VVQGEQFVGL IAMQDTLRQD AIDAIRALKK
     QGVNAVMLTG DNPRAAAAIA AQLGIDYRAG LLPEDKVKAV TELNEKHHTM MVGDGINDAP
     AMKAASIGVA MGSGTDVALE TADAALTHNR LTGLPEMIAL SRTTHYNIRQ NITIALGLKA
     IFLITSLLGI TGLWMAVLAD SGATALVTAN AIRLLRVKSQ KR
//

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