(data stored in SCRATCH zone)

SWISSPROT: D3VHY0_XENNA

ID   D3VHY0_XENNA            Unreviewed;       416 AA.
AC   D3VHY0;
DT   20-APR-2010, integrated into UniProtKB/TrEMBL.
DT   20-APR-2010, sequence version 1.
DT   16-JAN-2019, entry version 47.
DE   RecName: Full=Lipid III flippase {ECO:0000256|HAMAP-Rule:MF_02024};
GN   Name=wzxE {ECO:0000256|HAMAP-Rule:MF_02024,
GN   ECO:0000313|EMBL:CBJ88469.1};
GN   OrderedLocusNames=XNC1_0392 {ECO:0000313|EMBL:CBJ88469.1};
OS   Xenorhabdus nematophila (strain ATCC 19061 / DSM 3370 / LMG 1036 /
OS   NCIB 9965 / AN6).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Morganellaceae; Xenorhabdus.
OX   NCBI_TaxID=406817 {ECO:0000313|EMBL:CBJ88469.1, ECO:0000313|Proteomes:UP000008075};
RN   [1] {ECO:0000313|Proteomes:UP000008075}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 19061 / DSM 3370 / LMG 1036 / NCIB 9965 / AN6
RC   {ECO:0000313|Proteomes:UP000008075};
RA   Goodrich-Blair H., Barbazuk B., Bode H.B., Darby C., Du Z., Forst S.,
RA   Gaudriault S., Goldman B.S., Goodner B., Henkhaus J., Latreille P.,
RA   Medigue C., Miller N., Norton S., Ogier J.C., Rouy Z., Slater S.,
RA   Suen G.;
RT   "Complete genome sequence of Xenorhabdus nematophila (strain ATCC
RT   19061 / DSM 3370 / LMG 1036 / NCIB 9965 / AN6).";
RL   Submitted (FEB-2010) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EMBL:CBJ88469.1, ECO:0000313|Proteomes:UP000008075}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 19061 / DSM 3370 / LMG 1036 / NCIB 9965 / AN6
RC   {ECO:0000313|Proteomes:UP000008075};
RX   PubMed=22125637; DOI=10.1371/journal.pone.0027909;
RA   Chaston J.M., Suen G., Tucker S.L., Andersen A.W., Bhasin A., Bode E.,
RA   Bode H.B., Brachmann A.O., Cowles C.E., Cowles K.N., Darby C.,
RA   de Leon L., Drace K., Du Z., Givaudan A., Herbert Tran E.E.,
RA   Jewell K.A., Knack J.J., Krasomil-Osterfeld K.C., Kukor R., Lanois A.,
RA   Latreille P., Leimgruber N.K., Lipke C.M., Liu R., Lu X.,
RA   Martens E.C., Marri P.R., Medigue C., Menard M.L., Miller N.M.,
RA   Morales-Soto N., Norton S., Ogier J.C., Orchard S.S., Park D.,
RA   Park Y., Qurollo B.A., Sugar D.R., Richards G.R., Rouy Z.,
RA   Slominski B., Slominski K., Snyder H., Tjaden B.C., van der Hoeven R.,
RA   Welch R.D., Wheeler C., Xiang B., Barbazuk B., Gaudriault S.,
RA   Goodner B., Slater S.C., Forst S., Goldman B.S., Goodrich-Blair H.;
RT   "The entomopathogenic bacterial endosymbionts xenorhabdus and
RT   photorhabdus: convergent lifestyles from divergent genomes.";
RL   PLoS ONE 6:e27909-e27909(2011).
CC   -!- FUNCTION: Mediates the transbilayer movement of Und-PP-GlcNAc-
CC       ManNAcA-Fuc4NAc (lipid III) from the inner to the outer leaflet of
CC       the cytoplasmic membrane during the assembly of enterobacterial
CC       common antigen (ECA). {ECO:0000256|HAMAP-Rule:MF_02024}.
CC   -!- PATHWAY: Bacterial outer membrane biogenesis; enterobacterial
CC       common antigen biosynthesis. {ECO:0000256|HAMAP-Rule:MF_02024}.
CC   -!- SUBUNIT: Probably part of a complex composed of WzxE, WzyE and
CC       WzzE. {ECO:0000256|HAMAP-Rule:MF_02024}.
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000256|HAMAP-
CC       Rule:MF_02024}; Multi-pass membrane protein {ECO:0000256|HAMAP-
CC       Rule:MF_02024}.
CC   -!- SIMILARITY: Belongs to the polysaccharide transport (PST)
CC       (TC 2.A.66.2) family. {ECO:0000256|HAMAP-Rule:MF_02024}.
CC   -----------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   -----------------------------------------------------------------------
DR   EMBL; FN667742; CBJ88469.1; -; Genomic_DNA.
DR   RefSeq; WP_013183251.1; NC_014228.1.
DR   STRING; 406817.XNC1_0392; -.
DR   EnsemblBacteria; CBJ88469; CBJ88469; XNC1_0392.
DR   KEGG; xne:XNC1_0392; -.
DR   eggNOG; ENOG4105EGZ; Bacteria.
DR   eggNOG; COG2244; LUCA.
DR   HOGENOM; HOG000126459; -.
DR   KO; K16693; -.
DR   OMA; KFTIMAL; -.
DR   UniPathway; UPA00566; -.
DR   Proteomes; UP000008075; Chromosome.
DR   GO; GO:0005887; C:integral component of plasma membrane; IEA:UniProtKB-UniRule.
DR   GO; GO:0009246; P:enterobacterial common antigen biosynthetic process; IEA:UniProtKB-UniRule.
DR   HAMAP; MF_02024; WzxE; 1.
DR   InterPro; IPR002797; Polysacc_synth.
DR   InterPro; IPR032896; WzxE.
DR   Pfam; PF01943; Polysacc_synt; 1.
PE   3: Inferred from homology;
DR   PRODOM; D3VHY0.
DR   SWISS-2DPAGE; D3VHY0.
KW   Cell inner membrane {ECO:0000256|HAMAP-Rule:MF_02024};
KW   Cell membrane {ECO:0000256|HAMAP-Rule:MF_02024};
KW   Complete proteome {ECO:0000313|Proteomes:UP000008075};
KW   Membrane {ECO:0000256|HAMAP-Rule:MF_02024};
KW   Reference proteome {ECO:0000313|Proteomes:UP000008075};
KW   Transmembrane {ECO:0000256|HAMAP-Rule:MF_02024};
KW   Transmembrane helix {ECO:0000256|HAMAP-Rule:MF_02024};
KW   Transport {ECO:0000256|HAMAP-Rule:MF_02024}.
FT   TRANSMEM     12     33       Helical. {ECO:0000256|HAMAP-Rule:
FT                                MF_02024}.
FT   TRANSMEM     45     67       Helical. {ECO:0000256|HAMAP-Rule:
FT                                MF_02024}.
FT   TRANSMEM     79    101       Helical. {ECO:0000256|HAMAP-Rule:
FT                                MF_02024}.
FT   TRANSMEM    117    137       Helical. {ECO:0000256|HAMAP-Rule:
FT                                MF_02024}.
FT   TRANSMEM    149    170       Helical. {ECO:0000256|HAMAP-Rule:
FT                                MF_02024}.
FT   TRANSMEM    176    196       Helical. {ECO:0000256|HAMAP-Rule:
FT                                MF_02024}.
FT   TRANSMEM    217    237       Helical. {ECO:0000256|HAMAP-Rule:
FT                                MF_02024}.
FT   TRANSMEM    257    278       Helical. {ECO:0000256|HAMAP-Rule:
FT                                MF_02024}.
FT   TRANSMEM    299    322       Helical. {ECO:0000256|HAMAP-Rule:
FT                                MF_02024}.
FT   TRANSMEM    334    355       Helical. {ECO:0000256|HAMAP-Rule:
FT                                MF_02024}.
FT   TRANSMEM    362    382       Helical. {ECO:0000256|HAMAP-Rule:
FT                                MF_02024}.
FT   TRANSMEM    394    412       Helical. {ECO:0000256|HAMAP-Rule:
FT                                MF_02024}.
SQ   SEQUENCE   416 AA;  45515 MW;  0ECF0AFA82EEA67B CRC64;
     MSLAKASVWT AGSTLIKIGV GLLVIKLLAV SFGPTGVGQA GNFRQLITVL GVLSGAGIFN
     GVTKYVAEYH QQPERLSALL GTSSSIILGF STLLAVIFLL FSDAISVGLF GHNHYKIVVQ
     ALAFIQMGIA YANYFLAILK GFRDAQGNAL AIILGSLVGV IAYSLCYWLG GYEGTLAGLA
     LVPALVVLPA GMMILHRKVM AFSSLKPLWD RAIASHLGKF TLMALLTSIT LPVAYIMMRN
     LLAARYSWED VGIWQGVSSI SDAYLQFITA SFTVYLLPTL SRLESRQEIS REIVKALKFV
     LPAVAAASFS VWLLRDFVIW LLFSDKFTAM RDLFVWQLVG DVLKVGAYVF GYLVIAKAAL
     RFYILTEVSQ FLLLTGFSHW LIPMNGALGA AQSYMATYIV YFILCCSVFI IYRRRA
//

If you have problems or comments...

PBIL Back to PBIL home page