(data stored in ACNUC1829 zone)

SWISSPROT: D3YXN7_MOUSE

ID   D3YXN7_MOUSE            Unreviewed;       172 AA.
AC   D3YXN7;
DT   20-APR-2010, integrated into UniProtKB/TrEMBL.
DT   20-APR-2010, sequence version 1.
DT   05-JUL-2017, entry version 51.
DE   RecName: Full=Tetraspanin {ECO:0000256|RuleBase:RU361218};
DE   Flags: Fragment;
GN   Name=Tspan9 {ECO:0000313|Ensembl:ENSMUSP00000115922,
GN   ECO:0000313|MGI:MGI:1924558};
OS   Mus musculus (Mouse).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
OC   Muroidea; Muridae; Murinae; Mus; Mus.
OX   NCBI_TaxID=10090 {ECO:0000313|Ensembl:ENSMUSP00000115922, ECO:0000313|Proteomes:UP000000589};
RN   [1] {ECO:0000313|Ensembl:ENSMUSP00000115922, ECO:0000313|Proteomes:UP000000589}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000115922,
RC   ECO:0000313|Proteomes:UP000000589};
RX   PubMed=19468303; DOI=10.1371/journal.pbio.1000112;
RA   Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S.,
RA   She X., Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W.,
RA   Kapustin Y., Meric P., Maglott D., Birtle Z., Marques A.C., Graves T.,
RA   Zhou S., Teague B., Potamousis K., Churas C., Place M., Herschleb J.,
RA   Runnheim R., Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z.,
RA   Lindblad-Toh K., Eichler E.E., Ponting C.P.;
RT   "Lineage-specific biology revealed by a finished genome assembly of
RT   the mouse.";
RL   PLoS Biol. 7:E1000112-E1000112(2009).
RN   [2] {ECO:0000213|PubMed:21183079}
RP   IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RX   PubMed=21183079; DOI=10.1016/j.cell.2010.12.001;
RA   Huttlin E.L., Jedrychowski M.P., Elias J.E., Goswami T., Rad R.,
RA   Beausoleil S.A., Villen J., Haas W., Sowa M.E., Gygi S.P.;
RT   "A tissue-specific atlas of mouse protein phosphorylation and
RT   expression.";
RL   Cell 143:1174-1189(2010).
RN   [3] {ECO:0000313|Ensembl:ENSMUSP00000115922}
RP   IDENTIFICATION.
RC   STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000115922};
RG   Ensembl;
RL   Submitted (MAY-2011) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|RuleBase:RU361218};
CC       Multi-pass membrane protein {ECO:0000256|RuleBase:RU361218}.
CC   -!- SIMILARITY: Belongs to the tetraspanin (TM4SF) family.
CC       {ECO:0000256|RuleBase:RU361218, ECO:0000256|SAAS:SAAS00595319}.
CC   -!- CAUTION: Lacks conserved residue(s) required for the propagation
CC       of feature annotation. {ECO:0000256|RuleBase:RU361218}.
CC   -!- CAUTION: The sequence shown here is derived from an Ensembl
CC       automatic analysis pipeline and should be considered as
CC       preliminary data. {ECO:0000313|Ensembl:ENSMUSP00000115922}.
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DR   EMBL; AC135355; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AC144778; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   SMR; D3YXN7; -.
DR   MaxQB; D3YXN7; -.
DR   PaxDb; D3YXN7; -.
DR   PeptideAtlas; D3YXN7; -.
DR   Ensembl; ENSMUST00000123786; ENSMUSP00000115922; ENSMUSG00000030352.
DR   MGI; MGI:1924558; Tspan9.
DR   eggNOG; KOG3882; Eukaryota.
DR   eggNOG; ENOG4111IRY; LUCA.
DR   GeneTree; ENSGT00880000137858; -.
DR   HOGENOM; HOG000230651; -.
DR   ChiTaRS; Tspan9; mouse.
DR   Proteomes; UP000000589; Chromosome 6.
DR   Bgee; ENSMUSG00000030352; -.
DR   ExpressionAtlas; D3YXN7; baseline and differential.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-UniRule.
DR   Gene3D; 1.10.1450.10; -; 1.
DR   InterPro; IPR000301; Tetraspanin.
DR   InterPro; IPR018499; Tetraspanin/Peripherin.
DR   InterPro; IPR018503; Tetraspanin_CS.
DR   InterPro; IPR008952; Tetraspanin_EC2.
DR   Pfam; PF00335; Tetraspannin; 1.
DR   PRINTS; PR00259; TMFOUR.
DR   SUPFAM; SSF48652; SSF48652; 1.
DR   PROSITE; PS00421; TM4_1; 1.
PE   1: Evidence at protein level;
DR   PRODOM; D3YXN7.
DR   SWISS-2DPAGE; D3YXN7.
KW   Complete proteome {ECO:0000313|Proteomes:UP000000589};
KW   Membrane {ECO:0000256|RuleBase:RU361218,
KW   ECO:0000256|SAAS:SAAS00027997};
KW   Proteomics identification {ECO:0000213|MaxQB:D3YXN7,
KW   ECO:0000213|PeptideAtlas:D3YXN7};
KW   Reference proteome {ECO:0000313|Proteomes:UP000000589};
KW   Transmembrane {ECO:0000256|RuleBase:RU361218,
KW   ECO:0000256|SAAS:SAAS00429797};
KW   Transmembrane helix {ECO:0000256|RuleBase:RU361218,
KW   ECO:0000256|SAAS:SAAS00028005}.
FT   TRANSMEM     12     36       Helical. {ECO:0000256|RuleBase:RU361218}.
FT   TRANSMEM     56     76       Helical. {ECO:0000256|RuleBase:RU361218}.
FT   TRANSMEM     83    108       Helical. {ECO:0000256|RuleBase:RU361218}.
FT   NON_TER     172    172       {ECO:0000313|Ensembl:ENSMUSP00000115922}.
SQ   SEQUENCE   172 AA;  19106 MW;  11CADFD39D1DD075 CRC64;
     MARGCLCCLK YTMFLFNLIF WLCGCGLLGV GIWLSVSQGN FATFSPSFPS LSAANLVIAI
     GTIVMVTGFL GCLGAIKENK CLLLSFFIVL LIILLAELIL IILFFVYMDK VNENAKQDLK
     EGLLLYNTEN NVGLKNAWNI IQAEMRCCGV TDYTDWYPVL GENTVPDRCC ME
//

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