(data stored in SCRATCH zone)

SWISSPROT: D4YX14_SPHJU

ID   D4YX14_SPHJU            Unreviewed;       449 AA.
AC   D4YX14;
DT   15-JUN-2010, integrated into UniProtKB/TrEMBL.
DT   15-JUN-2010, sequence version 1.
DT   07-JUN-2017, entry version 45.
DE   RecName: Full=Histidine--tRNA ligase {ECO:0000256|HAMAP-Rule:MF_00127};
DE            EC=6.1.1.21 {ECO:0000256|HAMAP-Rule:MF_00127};
DE   AltName: Full=Histidyl-tRNA synthetase {ECO:0000256|HAMAP-Rule:MF_00127};
DE            Short=HisRS {ECO:0000256|HAMAP-Rule:MF_00127};
GN   Name=hisS {ECO:0000256|HAMAP-Rule:MF_00127,
GN   ECO:0000313|EMBL:BAI94896.1};
GN   OrderedLocusNames=SJA_C1-00620 {ECO:0000313|EMBL:BAI94896.1};
OS   Sphingobium japonicum (strain NBRC 101211 / UT26S).
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Sphingomonadales;
OC   Sphingomonadaceae; Sphingobium.
OX   NCBI_TaxID=452662 {ECO:0000313|EMBL:BAI94896.1, ECO:0000313|Proteomes:UP000007753};
RN   [1] {ECO:0000313|EMBL:BAI94896.1, ECO:0000313|Proteomes:UP000007753}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NBRC 101211 / UT26S {ECO:0000313|Proteomes:UP000007753};
RX   PubMed=20817768; DOI=10.1128/JB.00961-10;
RA   Nagata Y., Ohtsubo Y., Endo R., Ichikawa N., Ankai A., Oguchi A.,
RA   Fukui S., Fujita N., Tsuda M.;
RT   "Complete genome sequence of the representative gamma-
RT   hexachlorocyclohexane-degrading bacterium Sphingobium japonicum
RT   UT26.";
RL   J. Bacteriol. 192:5852-5853(2010).
CC   -!- CATALYTIC ACTIVITY: ATP + L-histidine + tRNA(His) = AMP +
CC       diphosphate + L-histidyl-tRNA(His). {ECO:0000256|HAMAP-
CC       Rule:MF_00127}.
CC   -!- SUBUNIT: Homodimer. {ECO:0000256|HAMAP-Rule:MF_00127}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00127}.
CC   -!- SIMILARITY: Belongs to the class-II aminoacyl-tRNA synthetase
CC       family. {ECO:0000256|HAMAP-Rule:MF_00127,
CC       ECO:0000256|SAAS:SAAS00676298}.
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DR   EMBL; AP010803; BAI94896.1; -; Genomic_DNA.
DR   RefSeq; WP_013038734.1; NC_014006.1.
DR   STRING; 452662.SJA_C1-00620; -.
DR   EnsemblBacteria; BAI94896; BAI94896; SJA_C1-00620.
DR   GeneID; 29271770; -.
DR   KEGG; sjp:SJA_C1-00620; -.
DR   eggNOG; ENOG4105CUT; Bacteria.
DR   eggNOG; COG0124; LUCA.
DR   HOGENOM; HOG000018072; -.
DR   KO; K01892; -.
DR   OMA; ARYVVMH; -.
DR   OrthoDB; POG091H021E; -.
DR   Proteomes; UP000007753; Chromosome 1.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-HAMAP.
DR   GO; GO:0004821; F:histidine-tRNA ligase activity; IEA:UniProtKB-HAMAP.
DR   GO; GO:0006427; P:histidyl-tRNA aminoacylation; IEA:UniProtKB-HAMAP.
DR   HAMAP; MF_00127; His_tRNA_synth; 1.
DR   InterPro; IPR006195; aa-tRNA-synth_II.
DR   InterPro; IPR015807; His-tRNA-ligase.
DR   InterPro; IPR004516; HisRS/HisZ.
DR   PANTHER; PTHR43707; PTHR43707; 1.
DR   PIRSF; PIRSF001549; His-tRNA_synth; 1.
DR   TIGRFAMs; TIGR00442; hisS; 1.
DR   PROSITE; PS50862; AA_TRNA_LIGASE_II; 1.
PE   3: Inferred from homology;
DR   PRODOM; D4YX14.
DR   SWISS-2DPAGE; D4YX14.
KW   Aminoacyl-tRNA synthetase {ECO:0000256|HAMAP-Rule:MF_00127,
KW   ECO:0000313|EMBL:BAI94896.1};
KW   ATP-binding {ECO:0000256|HAMAP-Rule:MF_00127};
KW   Complete proteome {ECO:0000313|Proteomes:UP000007753};
KW   Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00127};
KW   Ligase {ECO:0000256|HAMAP-Rule:MF_00127, ECO:0000313|EMBL:BAI94896.1};
KW   Nucleotide-binding {ECO:0000256|HAMAP-Rule:MF_00127};
KW   Protein biosynthesis {ECO:0000256|HAMAP-Rule:MF_00127};
KW   Reference proteome {ECO:0000313|Proteomes:UP000007753}.
FT   DOMAIN       31    330       AA_TRNA_LIGASE_II. {ECO:0000259|PROSITE:
FT                                PS50862}.
SQ   SEQUENCE   449 AA;  49859 MW;  EFD3955D3EDC9AAE CRC64;
     MAKIETPRPV RGTQDMLGGT NEAFQERFAH VVATFDRVRR LYGFQRVEVP VFESTAVFAR
     SLGESTDVVS KEMYTFEDRG GDSITLRPEF TAGISRAYIT EGWQQYAPLK VATHGPLFRY
     ERPQKGRFRQ FHQLDAEIIG AGEPGADVEL LVLADQLLRE LGISEGVTLN LNTLGDGPSR
     EAWRAALVAH FEAHRDQLSE ESIDRLHRNP LRILDSKDPR DRPVADSAPD IDAYLTDEAR
     SFFEKVTAGL DAAGVAWERN ARLVRGLDYY RHTAFEFITD RLGAQGTVLG GGRYDGLIEN
     LGGPSTPAVG WAAGIERLAM LIDVPAVERP KVVVFSEADD LEADIIKVTT ALRRAGIPAD
     SISGGSRKKR FDKAQSGNPE LLFVIRRSPN PRPNWNPIFI DVKRGRASPH EDFLLAEQDA
     AAFLNQAMIV VQLDEDEKKF ADFGVLLKS
//

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