(data stored in SCRATCH zone)

SWISSPROT: D4YXK7_SPHJU

ID   D4YXK7_SPHJU            Unreviewed;       140 AA.
AC   D4YXK7;
DT   15-JUN-2010, integrated into UniProtKB/TrEMBL.
DT   15-JUN-2010, sequence version 1.
DT   07-JUN-2017, entry version 42.
DE   RecName: Full=Ribosomal RNA large subunit methyltransferase H {ECO:0000256|HAMAP-Rule:MF_00658, ECO:0000256|SAAS:SAAS00702567};
DE            EC=2.1.1.177 {ECO:0000256|HAMAP-Rule:MF_00658, ECO:0000256|SAAS:SAAS00702569};
DE   AltName: Full=23S rRNA (pseudouridine1915-N3)-methyltransferase {ECO:0000256|HAMAP-Rule:MF_00658};
DE   AltName: Full=23S rRNA m3Psi1915 methyltransferase {ECO:0000256|HAMAP-Rule:MF_00658};
DE   AltName: Full=rRNA (pseudouridine-N3-)-methyltransferase RlmH {ECO:0000256|HAMAP-Rule:MF_00658};
GN   Name=ybeA {ECO:0000313|EMBL:BAI95089.1};
GN   Synonyms=rlmH {ECO:0000256|HAMAP-Rule:MF_00658};
GN   OrderedLocusNames=SJA_C1-02550 {ECO:0000313|EMBL:BAI95089.1};
OS   Sphingobium japonicum (strain NBRC 101211 / UT26S).
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Sphingomonadales;
OC   Sphingomonadaceae; Sphingobium.
OX   NCBI_TaxID=452662 {ECO:0000313|EMBL:BAI95089.1, ECO:0000313|Proteomes:UP000007753};
RN   [1] {ECO:0000313|EMBL:BAI95089.1, ECO:0000313|Proteomes:UP000007753}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NBRC 101211 / UT26S {ECO:0000313|Proteomes:UP000007753};
RX   PubMed=20817768; DOI=10.1128/JB.00961-10;
RA   Nagata Y., Ohtsubo Y., Endo R., Ichikawa N., Ankai A., Oguchi A.,
RA   Fukui S., Fujita N., Tsuda M.;
RT   "Complete genome sequence of the representative gamma-
RT   hexachlorocyclohexane-degrading bacterium Sphingobium japonicum
RT   UT26.";
RL   J. Bacteriol. 192:5852-5853(2010).
CC   -!- FUNCTION: Specifically methylates the pseudouridine at position
CC       1915 (m3Psi1915) in 23S rRNA. {ECO:0000256|HAMAP-Rule:MF_00658,
CC       ECO:0000256|SAAS:SAAS00702576}.
CC   -!- CATALYTIC ACTIVITY: S-adenosyl-L-methionine + pseudouridine(1915)
CC       in 23S rRNA = S-adenosyl-L-homocysteine + N(3)-
CC       methylpseudouridine(1915) in 23S rRNA. {ECO:0000256|HAMAP-
CC       Rule:MF_00658, ECO:0000256|SAAS:SAAS00702568}.
CC   -!- SUBUNIT: Homodimer. {ECO:0000256|HAMAP-Rule:MF_00658,
CC       ECO:0000256|SAAS:SAAS00702563}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00658,
CC       ECO:0000256|SAAS:SAAS00702564}.
CC   -!- SIMILARITY: Belongs to the RNA methyltransferase RlmH family.
CC       {ECO:0000256|HAMAP-Rule:MF_00658, ECO:0000256|SAAS:SAAS00702575}.
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DR   EMBL; AP010803; BAI95089.1; -; Genomic_DNA.
DR   RefSeq; WP_007686702.1; NC_014006.1.
DR   ProteinModelPortal; D4YXK7; -.
DR   STRING; 452662.SJA_C1-02550; -.
DR   EnsemblBacteria; BAI95089; BAI95089; SJA_C1-02550.
DR   GeneID; 29271958; -.
DR   KEGG; sjp:SJA_C1-02550; -.
DR   eggNOG; ENOG4108UXA; Bacteria.
DR   eggNOG; COG1576; LUCA.
DR   HOGENOM; HOG000218433; -.
DR   KO; K00783; -.
DR   OMA; NGEPYHK; -.
DR   OrthoDB; POG091H028B; -.
DR   Proteomes; UP000007753; Chromosome 1.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0070038; F:rRNA (pseudouridine-N3-)-methyltransferase activity; IEA:UniProtKB-HAMAP.
DR   Gene3D; 3.40.1280.10; -; 1.
DR   HAMAP; MF_00658; 23SrRNA_methyltr_H; 1.
DR   InterPro; IPR029028; Alpha/beta_knot_MTases.
DR   InterPro; IPR003742; RlmH-like.
DR   InterPro; IPR029026; tRNA_m1G_MTases_N.
DR   PANTHER; PTHR33603:SF2; PTHR33603:SF2; 1.
DR   Pfam; PF02590; SPOUT_MTase; 1.
DR   PIRSF; PIRSF004505; MT_bac; 2.
DR   SUPFAM; SSF75217; SSF75217; 1.
PE   3: Inferred from homology;
DR   PRODOM; D4YXK7.
DR   SWISS-2DPAGE; D4YXK7.
KW   Complete proteome {ECO:0000313|Proteomes:UP000007753};
KW   Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00658,
KW   ECO:0000256|SAAS:SAAS00702578};
KW   Methyltransferase {ECO:0000256|HAMAP-Rule:MF_00658,
KW   ECO:0000256|SAAS:SAAS00702579};
KW   Reference proteome {ECO:0000313|Proteomes:UP000007753};
KW   rRNA processing {ECO:0000256|HAMAP-Rule:MF_00658,
KW   ECO:0000256|SAAS:SAAS00702566};
KW   S-adenosyl-L-methionine {ECO:0000256|HAMAP-Rule:MF_00658,
KW   ECO:0000256|SAAS:SAAS00702581};
KW   Transferase {ECO:0000256|HAMAP-Rule:MF_00658,
KW   ECO:0000256|SAAS:SAAS00702565}.
SQ   SEQUENCE   140 AA;  15757 MW;  FC2996E5DC08A577 CRC64;
     MLLHIIARGK IGRSPEAELV DRYARRLTMP FRITELPDRG GKLPPAPPGT VTVMLDEKGR
     QLSSIDFARR IEGWRDSGKR ECRFLIGAAD GFDDAERDNA DLLIAFGAMT WPHMMARAML
     AEQLWRACSI LAGHPYHREG
//

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