(data stored in SCRATCH zone)

SWISSPROT: D5E905_METMS

ID   D5E905_METMS            Unreviewed;       291 AA.
AC   D5E905;
DT   15-JUN-2010, integrated into UniProtKB/TrEMBL.
DT   15-JUN-2010, sequence version 1.
DT   11-DEC-2019, entry version 44.
DE   RecName: Full=UTP--glucose-1-phosphate uridylyltransferase {ECO:0000256|RuleBase:RU361259};
DE            EC=2.7.7.9 {ECO:0000256|RuleBase:RU361259};
DE   AltName: Full=UDP-glucose pyrophosphorylase {ECO:0000256|RuleBase:RU361259};
GN   OrderedLocusNames=Mmah_0120 {ECO:0000313|EMBL:ADE35656.1};
OS   Methanohalophilus mahii (strain ATCC 35705 / DSM 5219 / SLP).
OC   Archaea; Euryarchaeota; Stenosarchaea group; Methanomicrobia;
OC   Methanosarcinales; Methanosarcinaceae; Methanohalophilus.
OX   NCBI_TaxID=547558 {ECO:0000313|EMBL:ADE35656.1, ECO:0000313|Proteomes:UP000001059};
RN   [1] {ECO:0000313|EMBL:ADE35656.1, ECO:0000313|Proteomes:UP000001059}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 35705 / DSM 5219 / SLP
RC   {ECO:0000313|Proteomes:UP000001059};
RG   US DOE Joint Genome Institute (JGI-PGF);
RA   Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E., Tice H.,
RA   Bruce D., Goodwin L., Pitluck S., Kyrpides N., Mavromatis K., Ivanova N.,
RA   Lykidis A., Saunders E., Brettin T., Detter J.C., Han C., Land M.,
RA   Hauser L., Markowitz V., Cheng J.-F., Hugenholtz P., Woyke T., Wu D.,
RA   Spring S., Schneider S., Schroeder M., Klenk H.-P., Eisen J.A.;
RT   "The complete genome of Methanohalophilus mahii DSM 5219.";
RL   Submitted (MAR-2010) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=alpha-D-glucose 1-phosphate + H(+) + UTP = diphosphate + UDP-
CC         alpha-D-glucose; Xref=Rhea:RHEA:19889, ChEBI:CHEBI:15378,
CC         ChEBI:CHEBI:33019, ChEBI:CHEBI:46398, ChEBI:CHEBI:58601,
CC         ChEBI:CHEBI:58885; EC=2.7.7.9;
CC         Evidence={ECO:0000256|RuleBase:RU361259};
CC   -!- SIMILARITY: Belongs to the UDPGP type 2 family.
CC       {ECO:0000256|RuleBase:RU361259}.
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DR   EMBL; CP001994; ADE35656.1; -; Genomic_DNA.
DR   EnsemblBacteria; ADE35656; ADE35656; Mmah_0120.
DR   KEGG; mmh:Mmah_0120; -.
DR   eggNOG; arCOG00665; Archaea.
DR   eggNOG; COG1210; LUCA.
DR   HOGENOM; HOG000283477; -.
DR   KO; K00963; -.
DR   OMA; MHYVRQG; -.
DR   BioCyc; MMAH547558:G1GHT-119-MONOMER; -.
DR   Proteomes; UP000001059; Chromosome.
DR   GO; GO:0003983; F:UTP:glucose-1-phosphate uridylyltransferase activity; IEA:UniProtKB-EC.
DR   GO; GO:0009058; P:biosynthetic process; IEA:InterPro.
DR   GO; GO:0006011; P:UDP-glucose metabolic process; IEA:InterPro.
DR   CDD; cd02541; UGPase_prokaryotic; 1.
DR   Gene3D; 3.90.550.10; -; 1.
DR   InterPro; IPR005771; GalU_uridylyltTrfase_bac/arc.
DR   InterPro; IPR005835; NTP_transferase_dom.
DR   InterPro; IPR029044; Nucleotide-diphossugar_trans.
DR   PANTHER; PTHR43197; PTHR43197; 1.
DR   Pfam; PF00483; NTP_transferase; 1.
DR   SUPFAM; SSF53448; SSF53448; 1.
DR   TIGRFAMs; TIGR01099; galU; 1.
PE   3: Inferred from homology;
DR   PRODOM; D5E905.
DR   SWISS-2DPAGE; D5E905.
KW   Nucleotidyltransferase {ECO:0000256|RuleBase:RU361259,
KW   ECO:0000313|EMBL:ADE35656.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001059};
KW   Transferase {ECO:0000256|RuleBase:RU361259, ECO:0000313|EMBL:ADE35656.1}.
FT   DOMAIN          5..263
FT                   /note="NTP_transferase"
FT                   /evidence="ECO:0000259|Pfam:PF00483"
SQ   SEQUENCE   291 AA;  32610 MW;  A088730C9A11A79E CRC64;
     MDVKKAVIPV AGLGTRFLPV TKSMPKEMLP IIDTPVIHYV VQEAIESGID DIIFVTGRNK
     RAIEDYFDGC PELEMHLKNR GKYDMLEMVQ EISSMVDIHY IRQKEPNGLG DAIMTARKHV
     SGDPFAVLLG DDIIVNEKPC TRQLIDVFRK YGRSTIAVEE VPQDKVSSYG IISGSPVDEY
     LYALDDIVEK PSVEEAPSNI GAIGRYVFTP EIFDCIEQTS KGVGGEIQLT DGIRLLNDSQ
     KVYAHQFTGR RYDSGNKVEY VKAVLDFAMK DDGMREEIQQ HLQNLGPITH D
//

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