(data stored in SCRATCH zone)

SWISSPROT: D5E9R9_METMS

ID   D5E9R9_METMS            Unreviewed;       245 AA.
AC   D5E9R9;
DT   15-JUN-2010, integrated into UniProtKB/TrEMBL.
DT   15-JUN-2010, sequence version 1.
DT   11-DEC-2019, entry version 52.
DE   RecName: Full=DNA polymerase sliding clamp {ECO:0000256|HAMAP-Rule:MF_00317};
DE   AltName: Full=Proliferating cell nuclear antigen homolog {ECO:0000256|HAMAP-Rule:MF_00317};
DE            Short=PCNA {ECO:0000256|HAMAP-Rule:MF_00317};
GN   Name=pcn {ECO:0000256|HAMAP-Rule:MF_00317};
GN   OrderedLocusNames=Mmah_0388 {ECO:0000313|EMBL:ADE35920.1};
OS   Methanohalophilus mahii (strain ATCC 35705 / DSM 5219 / SLP).
OC   Archaea; Euryarchaeota; Stenosarchaea group; Methanomicrobia;
OC   Methanosarcinales; Methanosarcinaceae; Methanohalophilus.
OX   NCBI_TaxID=547558 {ECO:0000313|EMBL:ADE35920.1, ECO:0000313|Proteomes:UP000001059};
RN   [1] {ECO:0000313|EMBL:ADE35920.1, ECO:0000313|Proteomes:UP000001059}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 35705 / DSM 5219 / SLP
RC   {ECO:0000313|Proteomes:UP000001059};
RG   US DOE Joint Genome Institute (JGI-PGF);
RA   Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E., Tice H.,
RA   Bruce D., Goodwin L., Pitluck S., Kyrpides N., Mavromatis K., Ivanova N.,
RA   Lykidis A., Saunders E., Brettin T., Detter J.C., Han C., Land M.,
RA   Hauser L., Markowitz V., Cheng J.-F., Hugenholtz P., Woyke T., Wu D.,
RA   Spring S., Schneider S., Schroeder M., Klenk H.-P., Eisen J.A.;
RT   "The complete genome of Methanohalophilus mahii DSM 5219.";
RL   Submitted (MAR-2010) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Sliding clamp subunit that acts as a moving platform for DNA
CC       processing. Responsible for tethering the catalytic subunit of DNA
CC       polymerase and other proteins to DNA during high-speed replication.
CC       {ECO:0000256|HAMAP-Rule:MF_00317}.
CC   -!- FUNCTION: Sliding clamp subunit. Responsible for tethering the
CC       catalytic subunit of DNA polymerase to DNA during high-speed
CC       replication. {ECO:0000256|RuleBase:RU003673}.
CC   -!- SUBUNIT: Homotrimer. The subunits circularize to form a toroid; DNA
CC       passes through its center. Replication factor C (RFC) is required to
CC       load the toroid on the DNA. {ECO:0000256|HAMAP-Rule:MF_00317}.
CC   -!- SIMILARITY: Belongs to the PCNA family. {ECO:0000256|HAMAP-
CC       Rule:MF_00317, ECO:0000256|RuleBase:RU003671}.
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DR   EMBL; CP001994; ADE35920.1; -; Genomic_DNA.
DR   RefSeq; WP_013036863.1; NC_014002.1.
DR   EnsemblBacteria; ADE35920; ADE35920; Mmah_0388.
DR   GeneID; 8982523; -.
DR   KEGG; mmh:Mmah_0388; -.
DR   eggNOG; arCOG00488; Archaea.
DR   eggNOG; COG0592; LUCA.
DR   HOGENOM; HOG000222371; -.
DR   KO; K04802; -.
DR   OMA; KCANSDD; -.
DR   OrthoDB; 70433at2157; -.
DR   BioCyc; MMAH547558:G1GHT-385-MONOMER; -.
DR   Proteomes; UP000001059; Chromosome.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0030337; F:DNA polymerase processivity factor activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
DR   GO; GO:0006275; P:regulation of DNA replication; IEA:UniProtKB-UniRule.
DR   HAMAP; MF_00317; DNApol_clamp_arch; 1.
DR   InterPro; IPR000730; Pr_cel_nuc_antig.
DR   InterPro; IPR022649; Pr_cel_nuc_antig_C.
DR   InterPro; IPR022659; Pr_cel_nuc_antig_CS.
DR   InterPro; IPR022648; Pr_cel_nuc_antig_N.
DR   PANTHER; PTHR11352:SF0; PTHR11352:SF0; 1.
DR   Pfam; PF02747; PCNA_C; 1.
DR   Pfam; PF00705; PCNA_N; 1.
DR   PRINTS; PR00339; PCNACYCLIN.
DR   PROSITE; PS01251; PCNA_1; 1.
PE   3: Inferred from homology;
DR   PRODOM; D5E9R9.
DR   SWISS-2DPAGE; D5E9R9.
KW   DNA replication {ECO:0000256|HAMAP-Rule:MF_00317,
KW   ECO:0000256|RuleBase:RU003671};
KW   DNA-binding {ECO:0000256|HAMAP-Rule:MF_00317,
KW   ECO:0000256|RuleBase:RU003671};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001059}.
FT   DOMAIN          1..98
FT                   /note="PCNA_N"
FT                   /evidence="ECO:0000259|Pfam:PF00705"
FT   DOMAIN          122..240
FT                   /note="PCNA_C"
FT                   /evidence="ECO:0000259|Pfam:PF02747"
SQ   SEQUENCE   245 AA;  26782 MW;  C0AD21B18CFA89B0 CRC64;
     MLEATIDASL LKDSIESLSV LVDEARVHIS PEGIGVKAVD PANVAMVSFE LQADAFDEYK
     AEESEIGLDL TRVLDILGVA EKTDKVKMKL EEDSRKLSIS IGGISYTLTL LDPSTIRAEP
     RIPQLELPAE IVINGKGFSR TVKAAEKISD HMSMGVEGET FFLEAEGDTE RMRQEMPRDE
     LISITPGPAR SLFSLDYLSD IVKPASKSNE VTLQIGNDFP IKINFEIAGG RGKVGYLLAP
     RIESE
//

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