(data stored in SCRATCH zone)

SWISSPROT: D5EA10_METMS

ID   D5EA10_METMS            Unreviewed;       358 AA.
AC   D5EA10;
DT   15-JUN-2010, integrated into UniProtKB/TrEMBL.
DT   15-JUN-2010, sequence version 1.
DT   11-DEC-2019, entry version 45.
DE   SubName: Full=L-lysine 2,3-aminomutase {ECO:0000313|EMBL:ADE36011.1};
DE            EC=5.4.3.2 {ECO:0000313|EMBL:ADE36011.1};
GN   OrderedLocusNames=Mmah_0483 {ECO:0000313|EMBL:ADE36011.1};
OS   Methanohalophilus mahii (strain ATCC 35705 / DSM 5219 / SLP).
OC   Archaea; Euryarchaeota; Stenosarchaea group; Methanomicrobia;
OC   Methanosarcinales; Methanosarcinaceae; Methanohalophilus.
OX   NCBI_TaxID=547558 {ECO:0000313|EMBL:ADE36011.1, ECO:0000313|Proteomes:UP000001059};
RN   [1] {ECO:0000313|EMBL:ADE36011.1, ECO:0000313|Proteomes:UP000001059}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 35705 / DSM 5219 / SLP
RC   {ECO:0000313|Proteomes:UP000001059};
RG   US DOE Joint Genome Institute (JGI-PGF);
RA   Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E., Tice H.,
RA   Bruce D., Goodwin L., Pitluck S., Kyrpides N., Mavromatis K., Ivanova N.,
RA   Lykidis A., Saunders E., Brettin T., Detter J.C., Han C., Land M.,
RA   Hauser L., Markowitz V., Cheng J.-F., Hugenholtz P., Woyke T., Wu D.,
RA   Spring S., Schneider S., Schroeder M., Klenk H.-P., Eisen J.A.;
RT   "The complete genome of Methanohalophilus mahii DSM 5219.";
RL   Submitted (MAR-2010) to the EMBL/GenBank/DDBJ databases.
CC   -!- COFACTOR:
CC       Name=pyridoxal 5'-phosphate; Xref=ChEBI:CHEBI:597326;
CC         Evidence={ECO:0000256|PIRSR:PIRSR603739-50};
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DR   EMBL; CP001994; ADE36011.1; -; Genomic_DNA.
DR   RefSeq; WP_013036954.1; NC_014002.1.
DR   EnsemblBacteria; ADE36011; ADE36011; Mmah_0483.
DR   GeneID; 8982624; -.
DR   KEGG; mmh:Mmah_0483; -.
DR   eggNOG; arCOG03246; Archaea.
DR   eggNOG; COG1509; LUCA.
DR   HOGENOM; HOG000223518; -.
DR   KO; K01843; -.
DR   OMA; VTNQCAM; -.
DR   OrthoDB; 10974at2157; -.
DR   BioCyc; MMAH547558:G1GHT-484-MONOMER; -.
DR   Proteomes; UP000001059; Chromosome.
DR   GO; GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.
DR   GO; GO:0050066; F:lysine 2,3-aminomutase activity; IEA:UniProtKB-EC.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   Gene3D; 3.20.20.70; -; 1.
DR   InterPro; IPR013785; Aldolase_TIM.
DR   InterPro; IPR025895; LAM_C_dom.
DR   InterPro; IPR003739; Lys_aminomutase/Glu_NH3_mut.
DR   InterPro; IPR007197; rSAM.
DR   PANTHER; PTHR30538; PTHR30538; 1.
DR   Pfam; PF12544; LAM_C; 1.
DR   Pfam; PF04055; Radical_SAM; 1.
DR   PIRSF; PIRSF004911; DUF160; 1.
DR   SFLD; SFLDG01070; PLP-dependent; 1.
DR   SFLD; SFLDS00029; Radical_SAM; 1.
DR   TIGRFAMs; TIGR00238; TIGR00238; 1.
PE   4: Predicted;
DR   PRODOM; D5EA10.
DR   SWISS-2DPAGE; D5EA10.
KW   4Fe-4S {ECO:0000256|PIRSR:PIRSR004911-1};
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Iron {ECO:0000256|PIRSR:PIRSR004911-1};
KW   Iron-sulfur {ECO:0000256|PIRSR:PIRSR004911-1};
KW   Isomerase {ECO:0000313|EMBL:ADE36011.1};
KW   Metal-binding {ECO:0000256|PIRSR:PIRSR004911-1};
KW   Pyridoxal phosphate {ECO:0000256|PIRSR:PIRSR603739-50};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001059}.
FT   DOMAIN          107..261
FT                   /note="Radical_SAM"
FT                   /evidence="ECO:0000259|Pfam:PF04055"
FT   DOMAIN          303..354
FT                   /note="LAM_C"
FT                   /evidence="ECO:0000259|Pfam:PF12544"
FT   COILED          2..36
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   METAL           112
FT                   /note="Iron-sulfur (4Fe-4S-S-AdoMet)"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR004911-1"
FT   METAL           116
FT                   /note="Iron-sulfur (4Fe-4S-S-AdoMet)"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR004911-1"
FT   METAL           119
FT                   /note="Iron-sulfur (4Fe-4S-S-AdoMet)"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR004911-1"
FT   MOD_RES         324
FT                   /note="N6-(pyridoxal phosphate)lysine"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR603739-50"
SQ   SEQUENCE   358 AA;  41495 MW;  746C46BDE450B755 CRC64;
     MSEEWKDQIT NQINSLEKLE EIINLTESER EAIKTLDTHW GTTPYFASLM DKDDPECPIR
     KQVVPSLQES HNKYGMKDYL VWKENRATEE VRPDSIARQY KDRVAFTVFQ ECGIYCRHCF
     RKELVVSHDL KLDFNVDDGI EWIRQHPEVR DVLITGGDPL LLSDEKIEYI IESLRDIPHV
     EMIRIGSRLP IVLPHRITDN LKRILGGYHD VPIWLNTQCN HPKEITDKTK RAVYDLVSAG
     VNVGNQAVLL KGINDDVQTI RDLHQKLLTA RIRPYYLFYC EPAPGIDHFR TPVEKGAELI
     RDGLRGHTTG LAQPMYVIAT NVGKIPLMPD YYMVDKDEEK YVLRNHRGEL TEIPNIPE
//

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