(data stored in SCRATCH zone)

SWISSPROT: D5EA57_METMS

ID   D5EA57_METMS            Unreviewed;       886 AA.
AC   D5EA57;
DT   15-JUN-2010, integrated into UniProtKB/TrEMBL.
DT   15-JUN-2010, sequence version 1.
DT   11-DEC-2019, entry version 44.
DE   RecName: Full=DNA-directed RNA polymerase subunit {ECO:0000256|RuleBase:RU004279};
DE            EC=2.7.7.6 {ECO:0000256|RuleBase:RU004279};
GN   OrderedLocusNames=Mmah_0531 {ECO:0000313|EMBL:ADE36058.1};
OS   Methanohalophilus mahii (strain ATCC 35705 / DSM 5219 / SLP).
OC   Archaea; Euryarchaeota; Stenosarchaea group; Methanomicrobia;
OC   Methanosarcinales; Methanosarcinaceae; Methanohalophilus.
OX   NCBI_TaxID=547558 {ECO:0000313|EMBL:ADE36058.1, ECO:0000313|Proteomes:UP000001059};
RN   [1] {ECO:0000313|EMBL:ADE36058.1, ECO:0000313|Proteomes:UP000001059}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 35705 / DSM 5219 / SLP
RC   {ECO:0000313|Proteomes:UP000001059};
RG   US DOE Joint Genome Institute (JGI-PGF);
RA   Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E., Tice H.,
RA   Bruce D., Goodwin L., Pitluck S., Kyrpides N., Mavromatis K., Ivanova N.,
RA   Lykidis A., Saunders E., Brettin T., Detter J.C., Han C., Land M.,
RA   Hauser L., Markowitz V., Cheng J.-F., Hugenholtz P., Woyke T., Wu D.,
RA   Spring S., Schneider S., Schroeder M., Klenk H.-P., Eisen J.A.;
RT   "The complete genome of Methanohalophilus mahii DSM 5219.";
RL   Submitted (MAR-2010) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: DNA-dependent RNA polymerase catalyzes the transcription of
CC       DNA into RNA using the four ribonucleoside triphosphates as substrates.
CC       {ECO:0000256|RuleBase:RU004279}.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate +
CC         RNA(n+1); Xref=Rhea:RHEA:21248, Rhea:RHEA-COMP:11128, Rhea:RHEA-
CC         COMP:11129, ChEBI:CHEBI:33019, ChEBI:CHEBI:61557, ChEBI:CHEBI:83400;
CC         EC=2.7.7.6; Evidence={ECO:0000256|RuleBase:RU004279};
CC   -!- SIMILARITY: Belongs to the RNA polymerase beta' chain family.
CC       {ECO:0000256|RuleBase:RU004279}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; CP001994; ADE36058.1; -; Genomic_DNA.
DR   EnsemblBacteria; ADE36058; ADE36058; Mmah_0531.
DR   KEGG; mmh:Mmah_0531; -.
DR   eggNOG; arCOG04257; Archaea.
DR   eggNOG; COG0086; LUCA.
DR   HOGENOM; HOG000222974; -.
DR   KO; K03041; -.
DR   OMA; AVCPPYN; -.
DR   Proteomes; UP000001059; Chromosome.
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0003899; F:DNA-directed 5'-3' RNA polymerase activity; IEA:UniProtKB-KW.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:InterPro.
DR   Gene3D; 1.10.132.30; -; 1.
DR   Gene3D; 1.10.274.100; -; 1.
DR   InterPro; IPR000722; RNA_pol_asu.
DR   InterPro; IPR006592; RNA_pol_N.
DR   InterPro; IPR007080; RNA_pol_Rpb1_1.
DR   InterPro; IPR007066; RNA_pol_Rpb1_3.
DR   InterPro; IPR042102; RNA_pol_Rpb1_3_sf.
DR   InterPro; IPR007083; RNA_pol_Rpb1_4.
DR   InterPro; IPR007081; RNA_pol_Rpb1_5.
DR   InterPro; IPR012758; RNAP_A1.
DR   InterPro; IPR038120; Rpb1_funnel_sf.
DR   Pfam; PF04997; RNA_pol_Rpb1_1; 1.
DR   Pfam; PF00623; RNA_pol_Rpb1_2; 1.
DR   Pfam; PF04983; RNA_pol_Rpb1_3; 1.
DR   Pfam; PF05000; RNA_pol_Rpb1_4; 1.
DR   Pfam; PF04998; RNA_pol_Rpb1_5; 1.
DR   SMART; SM00663; RPOLA_N; 1.
DR   TIGRFAMs; TIGR02390; RNA_pol_rpoA1; 1.
PE   3: Inferred from homology;
DR   PRODOM; D5EA57.
DR   SWISS-2DPAGE; D5EA57.
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   DNA-directed RNA polymerase {ECO:0000256|RuleBase:RU004279,
KW   ECO:0000313|EMBL:ADE36058.1};
KW   Nucleotidyltransferase {ECO:0000256|RuleBase:RU004279,
KW   ECO:0000313|EMBL:ADE36058.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001059};
KW   Transcription {ECO:0000256|RuleBase:RU004279};
KW   Transferase {ECO:0000256|RuleBase:RU004279, ECO:0000313|EMBL:ADE36058.1}.
FT   DOMAIN          211..515
FT                   /note="RPOLA_N"
FT                   /evidence="ECO:0000259|SMART:SM00663"
FT   COILED          663..690
FT                   /evidence="ECO:0000256|SAM:Coils"
SQ   SEQUENCE   886 AA;  99462 MW;  37952ABDFB15C445 CRC64;
     MMVISMDNTI PSIPQRIGAI RFGLLSPREI RKMSVTSIIT ADTYDDDGYP IDMGLMDLRL
     GVIDPGLKCK TCGGRAGECP GHFGHIELVA PVLHVGFNKI IRKILRSTCR NCSHLLLEDK
     QKKAYINQFA KLDVMSHLPD DLINNVFKEA RKTKICPYCG EEQLEIKFEK PSDYIENDYK
     LTPTEIRDRL ERIPDDDLKV MGMDPESARP EWMVLTVLAV PPVTVRPSIT LESGQRSEDD
     LTHKLVDIIR INQRFQENRD AGAPQLIIED LWELLQYHLT TFFDNEVSGV PPARHRSGRP
     LKTLTQRLKG KEGRFRGSLS GKRVNFSART VVSPDPNLSI NEVGVPYQIA KHMTIPVRVI
     SRNLEMMRAY VARGGETHPG ANYVFREDGR RLKITEANKE ELSEKLEPGW TVERQMQDGD
     IVLFNRQPSL HKMSIMAHKV KVLPNKTFKL NPAVCPPYNA DFDGDEMNMH VLQTEESRAE
     ANILMQVQEN ILSPRFGGPI IGGIHDHISG MFLLTRNENM ISKNDALELL RKSEVRELPE
     PAGYTDVGDP FWTGKQIFSQ ILPKDLNLEF KANVCFKCDV CKGRDCEYDA YVVVENGELV
     TGTIDEKAIG AFKGKILDSI VKRYGTTEAA QFVDDMTRLA IRGVMRTGLS FGISDEDIPR
     EAKLNIDEEL ERAENEVAEL IQAYEAKELE PLPGRTLAET IELKIMQSLG KARDHTGTIA
     GNHLGLENSA VIMAKSGARG SMLNLTQMAA CVGQQAVRGE RIRRGYEGRT LPHFDRGDLG
     ADAHGFVKSS YKSGLNPTEY FFHSVGGREG LVDTAVRTSQ SGYLQRRLVN ALQDLEVQYD
     RSVRETRGVI VQFKYGEDGI DSTKSDYSSE ETVHNIVRSV TGKEVK
//

If you have problems or comments...

PBIL Back to PBIL home page