(data stored in SCRATCH zone)

SWISSPROT: D5EA58_METMS

ID   D5EA58_METMS            Unreviewed;       385 AA.
AC   D5EA58;
DT   15-JUN-2010, integrated into UniProtKB/TrEMBL.
DT   15-JUN-2010, sequence version 1.
DT   11-DEC-2019, entry version 41.
DE   RecName: Full=DNA-directed RNA polymerase subunit A'' {ECO:0000256|HAMAP-Rule:MF_00411};
DE            EC=2.7.7.6 {ECO:0000256|HAMAP-Rule:MF_00411};
GN   Name=rpoA2 {ECO:0000256|HAMAP-Rule:MF_00411};
GN   OrderedLocusNames=Mmah_0532 {ECO:0000313|EMBL:ADE36059.1};
OS   Methanohalophilus mahii (strain ATCC 35705 / DSM 5219 / SLP).
OC   Archaea; Euryarchaeota; Stenosarchaea group; Methanomicrobia;
OC   Methanosarcinales; Methanosarcinaceae; Methanohalophilus.
OX   NCBI_TaxID=547558 {ECO:0000313|EMBL:ADE36059.1, ECO:0000313|Proteomes:UP000001059};
RN   [1] {ECO:0000313|EMBL:ADE36059.1, ECO:0000313|Proteomes:UP000001059}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 35705 / DSM 5219 / SLP
RC   {ECO:0000313|Proteomes:UP000001059};
RG   US DOE Joint Genome Institute (JGI-PGF);
RA   Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E., Tice H.,
RA   Bruce D., Goodwin L., Pitluck S., Kyrpides N., Mavromatis K., Ivanova N.,
RA   Lykidis A., Saunders E., Brettin T., Detter J.C., Han C., Land M.,
RA   Hauser L., Markowitz V., Cheng J.-F., Hugenholtz P., Woyke T., Wu D.,
RA   Spring S., Schneider S., Schroeder M., Klenk H.-P., Eisen J.A.;
RT   "The complete genome of Methanohalophilus mahii DSM 5219.";
RL   Submitted (MAR-2010) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: DNA-dependent RNA polymerase catalyzes the transcription of
CC       DNA into RNA using the four ribonucleoside triphosphates as substrates.
CC       {ECO:0000256|HAMAP-Rule:MF_00411}.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate +
CC         RNA(n+1); Xref=Rhea:RHEA:21248, Rhea:RHEA-COMP:11128, Rhea:RHEA-
CC         COMP:11129, ChEBI:CHEBI:33019, ChEBI:CHEBI:61557, ChEBI:CHEBI:83400;
CC         EC=2.7.7.6; Evidence={ECO:0000256|HAMAP-Rule:MF_00411};
CC   -!- SIMILARITY: Belongs to the RNA polymerase beta' chain family.
CC       {ECO:0000256|HAMAP-Rule:MF_00411}.
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DR   EMBL; CP001994; ADE36059.1; -; Genomic_DNA.
DR   RefSeq; WP_013037002.1; NC_014002.1.
DR   EnsemblBacteria; ADE36059; ADE36059; Mmah_0532.
DR   GeneID; 8982674; -.
DR   KEGG; mmh:Mmah_0532; -.
DR   eggNOG; arCOG04256; Archaea.
DR   eggNOG; COG0086; LUCA.
DR   HOGENOM; HOG000222986; -.
DR   KO; K03042; -.
DR   OMA; RPIGRHG; -.
DR   OrthoDB; 66811at2157; -.
DR   BioCyc; MMAH547558:G1GHT-535-MONOMER; -.
DR   Proteomes; UP000001059; Chromosome.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0003899; F:DNA-directed 5'-3' RNA polymerase activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-UniRule.
DR   CDD; cd06528; RNAP_A''; 1.
DR   HAMAP; MF_00411; RNApol_arch_A; 1.
DR   InterPro; IPR007081; RNA_pol_Rpb1_5.
DR   InterPro; IPR012757; RNAP_A2.
DR   Pfam; PF04998; RNA_pol_Rpb1_5; 1.
DR   TIGRFAMs; TIGR02389; RNA_pol_rpoA2; 1.
PE   3: Inferred from homology;
DR   PRODOM; D5EA58.
DR   SWISS-2DPAGE; D5EA58.
KW   DNA-directed RNA polymerase {ECO:0000256|HAMAP-Rule:MF_00411,
KW   ECO:0000313|EMBL:ADE36059.1};
KW   Nucleotidyltransferase {ECO:0000256|HAMAP-Rule:MF_00411,
KW   ECO:0000313|EMBL:ADE36059.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001059};
KW   Transcription {ECO:0000256|HAMAP-Rule:MF_00411};
KW   Transferase {ECO:0000256|HAMAP-Rule:MF_00411, ECO:0000313|EMBL:ADE36059.1}.
FT   DOMAIN          45..329
FT                   /note="RNA_pol_Rpb1_5"
FT                   /evidence="ECO:0000259|Pfam:PF04998"
SQ   SEQUENCE   385 AA;  42456 MW;  BB760486B07D6EEB CRC64;
     MVLQEATIEG MVKDLPLPSD VKLTLISDSV KAGVNKKQMG EIIEKLLETY DKSCVEPCEA
     VGVISAQSIG EPGTQMTMRT FHYAGVAEIN VTLGLPRLIE IVDARKRPST PMMTVHLDKE
     YLEDRDFANK IAWMIEATHV EHLADVTTDL PNMQLVIDLN EKAMNKREVG IESVMEKLEH
     GLGVSVVQAK EVSNQLLIKL KEPSYRELLQ LAKKINTITL KGIDGIKRVV VRKEDGEYRL
     YTEGSELKKV LEIDGVDPTR TSTNNIGEIY EVFGIEAARN AIIKEATDTL REQGLEVDVR
     HIMLVADIMS CDGEVKQIGR HGISGEKASV FARAAFEVTV NHLLDAGLRG EVDELSGVTE
     NIIVGQPIKL GTGDVHLVSR NPLQG
//

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