(data stored in SCRATCH zone)

SWISSPROT: D6XV76_BACIE

ID   D6XV76_BACIE            Unreviewed;       360 AA.
AC   D6XV76;
DT   10-AUG-2010, integrated into UniProtKB/TrEMBL.
DT   10-AUG-2010, sequence version 1.
DT   08-MAY-2019, entry version 73.
DE   RecName: Full=DNA integrity scanning protein DisA {ECO:0000256|SAAS:SAAS00724647};
DE            EC=2.7.7.85 {ECO:0000256|SAAS:SAAS00772190};
DE   AltName: Full=Diadenylate cyclase {ECO:0000256|SAAS:SAAS00772208};
GN   OrderedLocusNames=Bsel_0085 {ECO:0000313|EMBL:ADH97634.1};
OS   Bacillus selenitireducens (strain ATCC 700615 / DSM 15326 / MLS10).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Sporolactobacillaceae;
OC   unclassified Sporolactobacillaceae.
OX   NCBI_TaxID=439292 {ECO:0000313|EMBL:ADH97634.1, ECO:0000313|Proteomes:UP000000271};
RN   [1] {ECO:0000313|EMBL:ADH97634.1, ECO:0000313|Proteomes:UP000000271}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 700615 / DSM 15326 / MLS10
RC   {ECO:0000313|Proteomes:UP000000271};
RG   US DOE Joint Genome Institute;
RA   Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E.,
RA   Tice H., Bruce D., Goodwin L., Pitluck S., Sims D., Brettin T.,
RA   Detter J.C., Han C., Larimer F., Land M., Hauser L., Kyrpides N.,
RA   Ovchinnikova G., Stolz J.;
RT   "Complete sequence of Bacillus selenitireducens MLS10.";
RL   Submitted (OCT-2009) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=2 ATP = c-di-AMP + 2 diphosphate; Xref=Rhea:RHEA:35655,
CC         ChEBI:CHEBI:30616, ChEBI:CHEBI:33019, ChEBI:CHEBI:71500;
CC         EC=2.7.7.85; Evidence={ECO:0000256|SAAS:SAAS01115408};
CC   -!- COFACTOR:
CC       Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
CC         Evidence={ECO:0000256|SAAS:SAAS00724644};
CC   -!- SIMILARITY: Belongs to the DisA family.
CC       {ECO:0000256|SAAS:SAAS00724629}.
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DR   EMBL; CP001791; ADH97634.1; -; Genomic_DNA.
DR   RefSeq; WP_013171064.1; NC_014219.1.
DR   STRING; 439292.Bsel_0085; -.
DR   EnsemblBacteria; ADH97634; ADH97634; Bsel_0085.
DR   KEGG; bse:Bsel_0085; -.
DR   eggNOG; ENOG4105E59; Bacteria.
DR   eggNOG; COG1623; LUCA.
DR   HOGENOM; HOG000236713; -.
DR   KO; K07067; -.
DR   OMA; SKMDGAI; -.
DR   OrthoDB; 1139866at2; -.
DR   BioCyc; BSEL439292:G1GLR-109-MONOMER; -.
DR   Proteomes; UP000000271; Chromosome.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0016779; F:nucleotidyltransferase activity; IEA:UniProtKB-KW.
DR   GO; GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
DR   Gene3D; 1.20.1260.110; -; 1.
DR   Gene3D; 3.40.1700.10; -; 1.
DR   HAMAP; MF_01438; DisA; 1.
DR   InterPro; IPR038331; DisA_sf.
DR   InterPro; IPR036888; DNA_integrity_DisA_N_sf.
DR   InterPro; IPR018906; DNA_integrity_scan_DisA_link.
DR   InterPro; IPR003390; DNA_integrity_scan_DisA_N.
DR   InterPro; IPR023763; DNA_integrity_scanning_protein.
DR   InterPro; IPR010994; RuvA_2-like.
DR   Pfam; PF10635; DisA-linker; 1.
DR   Pfam; PF02457; DisA_N; 1.
DR   SUPFAM; SSF143597; SSF143597; 1.
DR   SUPFAM; SSF47781; SSF47781; 1.
DR   PROSITE; PS51794; DAC; 1.
PE   3: Inferred from homology;
DR   PRODOM; D6XV76.
DR   SWISS-2DPAGE; D6XV76.
KW   ATP-binding {ECO:0000256|SAAS:SAAS00772210};
KW   Complete proteome {ECO:0000313|Proteomes:UP000000271};
KW   DNA damage {ECO:0000256|SAAS:SAAS00724631};
KW   DNA repair {ECO:0000256|SAAS:SAAS00724636};
KW   DNA-binding {ECO:0000256|SAAS:SAAS00724650};
KW   Magnesium {ECO:0000256|SAAS:SAAS00724630};
KW   Nucleotide-binding {ECO:0000256|SAAS:SAAS00772222};
KW   Nucleotidyltransferase {ECO:0000256|SAAS:SAAS00772249};
KW   Reference proteome {ECO:0000313|Proteomes:UP000000271};
KW   Transferase {ECO:0000256|SAAS:SAAS00772224}.
FT   DOMAIN       10    148       DAC. {ECO:0000259|PROSITE:PS51794}.
SQ   SEQUENCE   360 AA;  40981 MW;  6017CB146E6A44E5 CRC64;
     MEHRNLSFDD SLTRRILTFV APGTPLREGI DNVLRANTGG LIVVGFNEEM QKIVNGGFYI
     NTDFSPAYLY ELAKMDGAII LNEDATRILY ANTQLVPENL IESTETGIRH RTAQRVAKQA
     GNLVISISQR RHVITLYQGR YRYSLKDIGV ILTKANQAIQ TLEKYKSVLD QSITNLGALE
     FEELVTFQEV SQVMHRIEMV LRIKSELMNY VIELGDEGRL ISMQLEELVL NIEQIALDLI
     MDYQKDSGTP PEDVLENLKR LSSDELLDDQ IIVKLFGYGK IVNLSDFPVS PRGYRILRKI
     PRIPPKVIRN LVRQFGTLSE MIRADIQELD EVEGIGEARA NKIQDGLSRI QEQLIIDRHI
//

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