(data stored in SCRATCH zone)

SWISSPROT: D6XX80_BACIE

ID   D6XX80_BACIE            Unreviewed;       271 AA.
AC   D6XX80;
DT   10-AUG-2010, integrated into UniProtKB/TrEMBL.
DT   10-AUG-2010, sequence version 1.
DT   08-MAY-2019, entry version 54.
DE   RecName: Full=Aminoglycoside N(3)-acetyltransferase {ECO:0000256|RuleBase:RU365031};
DE            EC=2.3.1.81 {ECO:0000256|RuleBase:RU365031};
GN   OrderedLocusNames=Bsel_0397 {ECO:0000313|EMBL:ADH97937.1};
OS   Bacillus selenitireducens (strain ATCC 700615 / DSM 15326 / MLS10).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Sporolactobacillaceae;
OC   unclassified Sporolactobacillaceae.
OX   NCBI_TaxID=439292 {ECO:0000313|EMBL:ADH97937.1, ECO:0000313|Proteomes:UP000000271};
RN   [1] {ECO:0000313|EMBL:ADH97937.1, ECO:0000313|Proteomes:UP000000271}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 700615 / DSM 15326 / MLS10
RC   {ECO:0000313|Proteomes:UP000000271};
RG   US DOE Joint Genome Institute;
RA   Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E.,
RA   Tice H., Bruce D., Goodwin L., Pitluck S., Sims D., Brettin T.,
RA   Detter J.C., Han C., Larimer F., Land M., Hauser L., Kyrpides N.,
RA   Ovchinnikova G., Stolz J.;
RT   "Complete sequence of Bacillus selenitireducens MLS10.";
RL   Submitted (OCT-2009) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=a 2-deoxystreptamine antibiotic + acetyl-CoA = a N(3')-
CC         acetyl-2-deoxystreptamine antibiotic + CoA + H(+);
CC         Xref=Rhea:RHEA:12665, ChEBI:CHEBI:15378, ChEBI:CHEBI:57287,
CC         ChEBI:CHEBI:57288, ChEBI:CHEBI:57921, ChEBI:CHEBI:77452;
CC         EC=2.3.1.81; Evidence={ECO:0000256|RuleBase:RU365031};
CC   -!- SIMILARITY: Belongs to the antibiotic N-acetyltransferase family.
CC       {ECO:0000256|RuleBase:RU365031}.
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DR   EMBL; CP001791; ADH97937.1; -; Genomic_DNA.
DR   RefSeq; WP_013171366.1; NC_014219.1.
DR   STRING; 439292.Bsel_0397; -.
DR   EnsemblBacteria; ADH97937; ADH97937; Bsel_0397.
DR   KEGG; bse:Bsel_0397; -.
DR   eggNOG; ENOG4108AQF; Bacteria.
DR   eggNOG; COG2746; LUCA.
DR   HOGENOM; HOG000030314; -.
DR   KO; K00662; -.
DR   OMA; TLVMPTH; -.
DR   OrthoDB; 1018324at2; -.
DR   BioCyc; BSEL439292:G1GLR-427-MONOMER; -.
DR   Proteomes; UP000000271; Chromosome.
DR   GO; GO:0046353; F:aminoglycoside 3-N-acetyltransferase activity; IEA:UniProtKB-EC.
DR   GO; GO:0046677; P:response to antibiotic; IEA:UniProtKB-KW.
DR   InterPro; IPR003679; Amioglycoside_AcTrfase.
DR   InterPro; IPR028345; Antibiotic_NAT-like.
DR   PANTHER; PTHR11104; PTHR11104; 1.
DR   Pfam; PF02522; Antibiotic_NAT; 1.
DR   SUPFAM; SSF110710; SSF110710; 1.
PE   3: Inferred from homology;
DR   PRODOM; D6XX80.
DR   SWISS-2DPAGE; D6XX80.
KW   Acyltransferase {ECO:0000256|RuleBase:RU365031,
KW   ECO:0000313|EMBL:ADH97937.1};
KW   Antibiotic resistance {ECO:0000256|RuleBase:RU365031};
KW   Complete proteome {ECO:0000313|Proteomes:UP000000271};
KW   Reference proteome {ECO:0000313|Proteomes:UP000000271};
KW   Transferase {ECO:0000256|RuleBase:RU365031,
KW   ECO:0000313|EMBL:ADH97937.1}.
SQ   SEQUENCE   271 AA;  29283 MW;  8D8E76BC760703E0 CRC64;
     MTNEIHASTV LNTVDTLTRD LKINGIEEGD LLLVHASLSA LGWVNGGSAA VIGALITAIG
     PDGTIVMPAQ SGDLSDPSEW EAPAVPQAWW QTIRDTMPAY DPAITQTRGI GTIAEHFRTW
     PGTDRSLHPA LSFSARGPLA RTVLHPHPLA CGLGEDSPLG RLYEHGAKVL FIGNGYDANT
     CFHLGEYIAP SPPMIEKGAP VLTDGVRQWI TYEEVDLDEE VFEEIGRTFE ETYPVHTGKI
     GDATAKVFAL RDAVDASTTW FTAHRQTQTA D
//

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