(data stored in SCRATCH zone)

SWISSPROT: D6XY18_BACIE

ID   D6XY18_BACIE            Unreviewed;       211 AA.
AC   D6XY18;
DT   10-AUG-2010, integrated into UniProtKB/TrEMBL.
DT   10-AUG-2010, sequence version 1.
DT   08-MAY-2019, entry version 60.
DE   RecName: Full=Redox-sensing transcriptional repressor Rex {ECO:0000256|HAMAP-Rule:MF_01131};
GN   Name=rex {ECO:0000256|HAMAP-Rule:MF_01131};
GN   OrderedLocusNames=Bsel_0555 {ECO:0000313|EMBL:ADH98091.1};
OS   Bacillus selenitireducens (strain ATCC 700615 / DSM 15326 / MLS10).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Sporolactobacillaceae;
OC   unclassified Sporolactobacillaceae.
OX   NCBI_TaxID=439292 {ECO:0000313|EMBL:ADH98091.1, ECO:0000313|Proteomes:UP000000271};
RN   [1] {ECO:0000313|EMBL:ADH98091.1, ECO:0000313|Proteomes:UP000000271}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 700615 / DSM 15326 / MLS10
RC   {ECO:0000313|Proteomes:UP000000271};
RG   US DOE Joint Genome Institute;
RA   Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E.,
RA   Tice H., Bruce D., Goodwin L., Pitluck S., Sims D., Brettin T.,
RA   Detter J.C., Han C., Larimer F., Land M., Hauser L., Kyrpides N.,
RA   Ovchinnikova G., Stolz J.;
RT   "Complete sequence of Bacillus selenitireducens MLS10.";
RL   Submitted (OCT-2009) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Modulates transcription in response to changes in
CC       cellular NADH/NAD(+) redox state. {ECO:0000256|HAMAP-
CC       Rule:MF_01131, ECO:0000256|SAAS:SAAS00345902}.
CC   -!- SUBUNIT: Homodimer. {ECO:0000256|HAMAP-Rule:MF_01131,
CC       ECO:0000256|SAAS:SAAS00345894}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_01131,
CC       ECO:0000256|SAAS:SAAS00345872}.
CC   -!- SIMILARITY: Belongs to the transcriptional regulatory Rex family.
CC       {ECO:0000256|HAMAP-Rule:MF_01131, ECO:0000256|SAAS:SAAS00541514}.
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DR   EMBL; CP001791; ADH98091.1; -; Genomic_DNA.
DR   RefSeq; WP_013171520.1; NC_014219.1.
DR   STRING; 439292.Bsel_0555; -.
DR   EnsemblBacteria; ADH98091; ADH98091; Bsel_0555.
DR   KEGG; bse:Bsel_0555; -.
DR   eggNOG; COG2344; LUCA.
DR   HOGENOM; HOG000250065; -.
DR   KO; K01926; -.
DR   OMA; QILAFHE; -.
DR   OrthoDB; 1872374at2; -.
DR   BioCyc; BSEL439292:G1GLR-596-MONOMER; -.
DR   Proteomes; UP000000271; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0050662; F:coenzyme binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IEA:InterPro.
DR   GO; GO:0051775; P:response to redox state; IEA:InterPro.
DR   Gene3D; 1.10.10.10; -; 1.
DR   HAMAP; MF_01131; Rex; 1.
DR   InterPro; IPR003781; CoA-bd.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   InterPro; IPR009718; Rex_DNA-bd_C_dom.
DR   InterPro; IPR022876; Tscrpt_rep_Rex.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   PANTHER; PTHR35786; PTHR35786; 1.
DR   Pfam; PF02629; CoA_binding; 1.
DR   Pfam; PF06971; Put_DNA-bind_N; 1.
DR   SMART; SM00881; CoA_binding; 1.
DR   SUPFAM; SSF46785; SSF46785; 1.
DR   SUPFAM; SSF51735; SSF51735; 1.
PE   3: Inferred from homology;
DR   PRODOM; D6XY18.
DR   SWISS-2DPAGE; D6XY18.
KW   Complete proteome {ECO:0000313|Proteomes:UP000000271};
KW   Cytoplasm {ECO:0000256|HAMAP-Rule:MF_01131,
KW   ECO:0000256|SAAS:SAAS00345885};
KW   DNA-binding {ECO:0000256|HAMAP-Rule:MF_01131,
KW   ECO:0000256|SAAS:SAAS00345893};
KW   NAD {ECO:0000256|HAMAP-Rule:MF_01131, ECO:0000256|SAAS:SAAS00424161};
KW   Reference proteome {ECO:0000313|Proteomes:UP000000271};
KW   Repressor {ECO:0000256|HAMAP-Rule:MF_01131,
KW   ECO:0000256|SAAS:SAAS00345859};
KW   Transcription {ECO:0000256|HAMAP-Rule:MF_01131,
KW   ECO:0000256|SAAS:SAAS00424131};
KW   Transcription regulation {ECO:0000256|HAMAP-Rule:MF_01131,
KW   ECO:0000256|SAAS:SAAS00345910}.
FT   DOMAIN       81    180       CoA_binding. {ECO:0000259|SMART:SM00881}.
FT   DNA_BIND     18     57       H-T-H motif. {ECO:0000256|HAMAP-Rule:
FT                                MF_01131}.
FT   NP_BIND      92     97       NAD. {ECO:0000256|HAMAP-Rule:MF_01131}.
SQ   SEQUENCE   211 AA;  23771 MW;  0A34174A403B2F74 CRC64;
     MEIDQAKIPQ ATAKRLPLYY RFLEGLQASG KHRVSSSELS EAVKVDSATI RRDFSYFGAL
     GKKGYGYNVN YLLSFFRKTL DQDELTKVAL VGVGNLGTAF LNYNFSKSNN TRIEMAFDVD
     RSKVDQVYGD VPVYHFDDIE EKIGDIEVVI LTVPSQAAQG ITDQLLECGI KGILNFTPAR
     LTVPDDIRVH HIDLSVELQS LIYFLKHYPL K
//

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