(data stored in SCRATCH zone)

SWISSPROT: D6ZCK5_SEGRD

ID   D6ZCK5_SEGRD            Unreviewed;      1062 AA.
AC   D6ZCK5;
DT   10-AUG-2010, integrated into UniProtKB/TrEMBL.
DT   10-AUG-2010, sequence version 1.
DT   08-MAY-2019, entry version 59.
DE   SubName: Full=UvrD/REP helicase {ECO:0000313|EMBL:ADG97047.1};
GN   OrderedLocusNames=Srot_0565 {ECO:0000313|EMBL:ADG97047.1};
OS   Segniliparus rotundus (strain ATCC BAA-972 / CDC 1076 / CIP 108378 /
OS   DSM 44985 / JCM 13578).
OC   Bacteria; Actinobacteria; Corynebacteriales; Segniliparaceae;
OC   Segniliparus.
OX   NCBI_TaxID=640132 {ECO:0000313|EMBL:ADG97047.1, ECO:0000313|Proteomes:UP000002247};
RN   [1] {ECO:0000313|EMBL:ADG97047.1, ECO:0000313|Proteomes:UP000002247}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC BAA-972 / CDC 1076 / CIP 108378 / DSM 44985 / JCM 13578
RC   {ECO:0000313|Proteomes:UP000002247};
RX   PubMed=21304703; DOI=10.4056/sigs.791633;
RA   Sikorski J., Lapidus A., Copeland A., Misra M., Glavina Del Rio T.,
RA   Nolan M., Lucas S., Chen F., Tice H., Cheng J.F., Jando M.,
RA   Schneider S., Bruce D., Goodwin L., Pitluck S., Liolios K.,
RA   Mikhailova N., Pati A., Ivanova N., Mavromatis K., Chen A.,
RA   Palaniappan K., Chertkov O., Land M., Hauser L., Chang Y.J.,
RA   Jeffries C.D., Brettin T., Detter J.C., Han C., Rohde M., Goker M.,
RA   Bristow J., Eisen J.A., Markowitz V., Hugenholtz P., Kyrpides N.C.,
RA   Klenk H.P.;
RT   "Complete genome sequence of Segniliparus rotundus type strain (CDC
RT   1076).";
RL   Stand. Genomic Sci. 2:203-211(2010).
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC         ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC         ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=3.6.4.12;
CC         Evidence={ECO:0000256|SAAS:SAAS01129065};
CC   -!- COFACTOR:
CC       Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
CC         Evidence={ECO:0000256|SAAS:SAAS01099290};
CC   -!- SIMILARITY: Belongs to the helicase family. UvrD subfamily.
CC       {ECO:0000256|SAAS:SAAS00709641}.
CC   -----------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   -----------------------------------------------------------------------
DR   EMBL; CP001958; ADG97047.1; -; Genomic_DNA.
DR   RefSeq; WP_013137503.1; NC_014168.1.
DR   STRING; 640132.Srot_0565; -.
DR   EnsemblBacteria; ADG97047; ADG97047; Srot_0565.
DR   KEGG; srt:Srot_0565; -.
DR   eggNOG; ENOG4106AQX; Bacteria.
DR   eggNOG; COG0210; LUCA.
DR   eggNOG; COG2887; LUCA.
DR   HOGENOM; HOG000247959; -.
DR   KO; K03657; -.
DR   OMA; SGHWWGP; -.
DR   OrthoDB; 137860at2; -.
DR   BioCyc; SROT640132:G1GLH-569-MONOMER; -.
DR   Proteomes; UP000002247; Chromosome.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004003; F:ATP-dependent DNA helicase activity; IEA:InterPro.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0004527; F:exonuclease activity; IEA:UniProtKB-KW.
DR   GO; GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
DR   InterPro; IPR014017; DNA_helicase_UvrD-like_C.
DR   InterPro; IPR000212; DNA_helicase_UvrD/REP.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR038726; PDDEXK_AddAB-type.
DR   InterPro; IPR011335; Restrct_endonuc-II-like.
DR   InterPro; IPR014016; UvrD-like_ATP-bd.
DR   InterPro; IPR034739; UvrD/AddA_N.
DR   PANTHER; PTHR11070; PTHR11070; 2.
DR   Pfam; PF12705; PDDEXK_1; 1.
DR   Pfam; PF00580; UvrD-helicase; 1.
DR   Pfam; PF13361; UvrD_C; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   SUPFAM; SSF52980; SSF52980; 1.
DR   PROSITE; PS51198; UVRD_HELICASE_ATP_BIND; 1.
DR   PROSITE; PS51217; UVRD_HELICASE_CTER; 1.
PE   3: Inferred from homology;
DR   PRODOM; D6ZCK5.
DR   SWISS-2DPAGE; D6ZCK5.
KW   ATP-binding {ECO:0000256|SAAS:SAAS00146071};
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Complete proteome {ECO:0000313|Proteomes:UP000002247};
KW   DNA damage {ECO:0000256|SAAS:SAAS01099294};
KW   DNA repair {ECO:0000256|SAAS:SAAS01099287};
KW   DNA-binding {ECO:0000256|SAAS:SAAS00745286};
KW   Exonuclease {ECO:0000256|SAAS:SAAS01033115};
KW   Helicase {ECO:0000256|SAAS:SAAS00553650, ECO:0000313|EMBL:ADG97047.1};
KW   Hydrolase {ECO:0000256|SAAS:SAAS00146062};
KW   Nuclease {ECO:0000256|SAAS:SAAS01033141};
KW   Nucleotide-binding {ECO:0000256|SAAS:SAAS00145996};
KW   Reference proteome {ECO:0000313|Proteomes:UP000002247}.
FT   DOMAIN       14    366       UvrD-like helicase ATP-binding.
FT                                {ECO:0000259|PROSITE:PS51198}.
FT   DOMAIN      367    676       UvrD-like helicase C-terminal.
FT                                {ECO:0000259|PROSITE:PS51217}.
FT   COILED      722    746       {ECO:0000256|SAM:Coils}.
SQ   SEQUENCE   1062 AA;  111943 MW;  B177A405DECFD134 CRC64;
     MIGPRLLAQA IGAPVPSEEQ EQVIGAPLAS SAVLAGAGSG KTETVAARVV WLIANGLVEP
     EHVLGLTFTR SAARGMLARV RARLAGFAAS PLLERVDPTG RLGELLENSE PQVMTYDAYA
     GELVSRWGLL LGASATEAAA GGRVVLSEAG MWQLAYETVA NWESLLSVDR GVAGVAEAVT
     ALGRRMAEQL AAPDRVLAAA EELARLVRTL PKGPRQRAEP SLELREAVAV QQARAELLGV
     VARMQDRLRS SGAVDFATQT ARAAELAQRF PQVRAEECAA HRVVLLDEYQ DTGHAQRILL
     RALFGPPRIG GAARGGGANG AAVTAVGDPH QAIYAWRGAS SGNLAAFQAD FGAPEALTLM
     TSWRNPASVL DLANLTAAPL RRAGIAVPEL AARPDAPAGE VRVALFDDAA AERAWIAERL
     RHAAQTSPTR PSMAVLVRRN ADAVPVAEAL TAAGLEAQVI GLGGLLATPQ VAELVAMLEL
     IADPGASAAA LQVLTSPRWR IGARDLAALA QRAQELGPGR ARPLAPRDPA ELVEQLTAVL
     ADDGSERAGL GDALADLGDQ GRYSAAGYAR LALLAGELDR LRGQLARPLP EFVTLVERVT
     GLAVEADAQA KERLSAFASV VAEHAKAAEL LGGSASLAGL VGYVRLAETV ERGLPVGEVA
     PDPRKVQVLT VHAAKGLEWD VVAVAHLCAG VFPTGRARST WIGALAELPP EDLGPLTSSQ
     DRAELQEMLR AEREAAKELA GEEERRLAYV AVTRAKQTLL LSGHWLAEGA ERALGPSAFL
     VEWRDALVAA GGSPDMWAES PALDHMRPAS GESEGALWPP DPLLGRRAQT QRGAERVRAA
     LADAVPLPRP EGPDAELYEA AAALVAERAA AAEARSVERA GLTVSDVVGI AVDPAGFERE
     RARRGPRPPA PEAQAGIGFH EWVRRWYLSE ELVGLDELPG AADDDDAVAS EKLRQKFLES
     PWAARSPVAV ETPFELNLDG VLVRGRIDAV FAEPGGGYVV VDWKTGRADL RRAKAQLSVY
     RLAWQRLTGA AQVAGAVHEV ATGVTRTFDD LYTAEELAAL LR
//

If you have problems or comments...

PBIL Back to PBIL home page