(data stored in SCRATCH zone)

SWISSPROT: D7A0X9_STAND

ID   D7A0X9_STAND            Unreviewed;       411 AA.
AC   D7A0X9;
DT   10-AUG-2010, integrated into UniProtKB/TrEMBL.
DT   10-AUG-2010, sequence version 1.
DT   08-MAY-2019, entry version 58.
DE   RecName: Full=Arginine deiminase {ECO:0000256|HAMAP-Rule:MF_00242};
DE            Short=ADI {ECO:0000256|HAMAP-Rule:MF_00242};
DE            EC=3.5.3.6 {ECO:0000256|HAMAP-Rule:MF_00242};
DE   AltName: Full=Arginine dihydrolase {ECO:0000256|HAMAP-Rule:MF_00242};
DE            Short=AD {ECO:0000256|HAMAP-Rule:MF_00242};
GN   Name=arcA {ECO:0000256|HAMAP-Rule:MF_00242};
GN   OrderedLocusNames=Snov_0153 {ECO:0000313|EMBL:ADH87489.1};
OS   Starkeya novella (strain ATCC 8093 / DSM 506 / CCM 1077 / IAM 12100 /
OS   NBRC 12443 / NCIB 9113).
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Rhizobiales;
OC   Xanthobacteraceae; Starkeya.
OX   NCBI_TaxID=639283 {ECO:0000313|EMBL:ADH87489.1, ECO:0000313|Proteomes:UP000006633};
RN   [1] {ECO:0000313|Proteomes:UP000006633}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 8093 / DSM 506 / CCM 1077 / IAM 12100 / NBRC 12443 / NCIB
RC   9113 {ECO:0000313|Proteomes:UP000006633};
RG   US DOE Joint Genome Institute;
RA   Lucas S., Copeland A., Lapidus A., Cheng J.-F., Bruce D., Goodwin L.,
RA   Pitluck S., Davenport K., Brettin T., Detter J.C., Han C., Tapia R.,
RA   Land M., Hauser L., Kyrpides N., Ivanova N., Beatson S., Kappler U.,
RA   Woyke T.;
RT   "Complete sequence of Starkeya novella DSM 506.";
RL   Submitted (MAY-2010) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EMBL:ADH87489.1, ECO:0000313|Proteomes:UP000006633}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 8093 / DSM 506 / CCM 1077 / IAM 12100 / NBRC 12443 / NCIB
RC   9113 {ECO:0000313|Proteomes:UP000006633};
RX   PubMed=23450099; DOI=10.4056/sigs.3006378;
RA   Kappler U., Davenport K., Beatson S., Lucas S., Lapidus A.,
RA   Copeland A., Berry K.W., Glavina Del Rio T., Hammon N., Dalin E.,
RA   Tice H., Pitluck S., Richardson P., Bruce D., Goodwin L.A., Han C.,
RA   Tapia R., Detter J.C., Chang Y.J., Jeffries C.D., Land M., Hauser L.,
RA   Kyrpides N.C., Goker M., Ivanova N., Klenk H.P., Woyke T.;
RT   "Complete genome sequence of the facultatively chemolithoautotrophic
RT   and methylotrophic alpha Proteobacterium Starkeya novella type strain
RT   (ATCC 8093(T)).";
RL   Stand. Genomic Sci. 7:44-58(2012).
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=H2O + L-arginine = L-citrulline + NH4(+);
CC         Xref=Rhea:RHEA:19597, ChEBI:CHEBI:15377, ChEBI:CHEBI:28938,
CC         ChEBI:CHEBI:32682, ChEBI:CHEBI:57743; EC=3.5.3.6;
CC         Evidence={ECO:0000256|HAMAP-Rule:MF_00242,
CC         ECO:0000256|SAAS:SAAS01179092};
CC   -!- PATHWAY: Amino-acid degradation; L-arginine degradation via ADI
CC       pathway; carbamoyl phosphate from L-arginine: step 1/2.
CC       {ECO:0000256|HAMAP-Rule:MF_00242, ECO:0000256|SAAS:SAAS00092991}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00242,
CC       ECO:0000256|SAAS:SAAS00092998}.
CC   -!- SIMILARITY: Belongs to the arginine deiminase family.
CC       {ECO:0000256|HAMAP-Rule:MF_00242, ECO:0000256|SAAS:SAAS01179091}.
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DR   EMBL; CP002026; ADH87489.1; -; Genomic_DNA.
DR   RefSeq; WP_013164994.1; NC_014217.1.
DR   STRING; 639283.Snov_0153; -.
DR   EnsemblBacteria; ADH87489; ADH87489; Snov_0153.
DR   KEGG; sno:Snov_0153; -.
DR   eggNOG; ENOG4105CEU; Bacteria.
DR   eggNOG; COG2235; LUCA.
DR   HOGENOM; HOG000284536; -.
DR   KO; K01478; -.
DR   OMA; QRDNSAW; -.
DR   OrthoDB; 592329at2; -.
DR   BioCyc; SNOV639283:G1GLM-155-MONOMER; -.
DR   UniPathway; UPA00254; UER00364.
DR   Proteomes; UP000006633; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0016990; F:arginine deiminase activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0019547; P:arginine catabolic process to ornithine; IEA:UniProtKB-UniPathway.
DR   HAMAP; MF_00242; Arg_deiminase; 1.
DR   InterPro; IPR003876; Arg_deiminase.
DR   PIRSF; PIRSF006356; Arg_deiminase; 1.
DR   PRINTS; PR01466; ARGDEIMINASE.
PE   3: Inferred from homology;
DR   PRODOM; D7A0X9.
DR   SWISS-2DPAGE; D7A0X9.
KW   Arginine metabolism {ECO:0000256|HAMAP-Rule:MF_00242,
KW   ECO:0000256|SAAS:SAAS00463711};
KW   Complete proteome {ECO:0000313|Proteomes:UP000006633};
KW   Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00242,
KW   ECO:0000256|SAAS:SAAS00463701};
KW   Hydrolase {ECO:0000256|HAMAP-Rule:MF_00242,
KW   ECO:0000256|SAAS:SAAS00093005, ECO:0000313|EMBL:ADH87489.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000006633}.
FT   ACT_SITE    399    399       Amidino-cysteine intermediate.
FT                                {ECO:0000256|HAMAP-Rule:MF_00242,
FT                                ECO:0000256|PIRSR:PIRSR006356-1}.
SQ   SEQUENCE   411 AA;  45396 MW;  EE290C9B0694317C CRC64;
     METSFGVHSE VGQLRKVLVC APGRAHQRLT PSNCDALLFD DVLWVDVAKR DHFDFITKMR
     DRGIEVVEMH NLLTETLAVP EAKKWILDNQ VAPNQIGLGF VEEVRSYLEG LPNRQLAETL
     IGGLSTYEFP ETIGGETLAL IRDAAGVNEY LLPPLPNTLY TRDTTCWIYG GVTLNPLYWP
     ARHEETILTS SIYKFHPDFA GKVNVWWGDP TKDWGLATLE GGDVMPIGKG NVLIGMSERT
     SRQAISQAAA ALFEKGGAER VIVAAMPKLR AAMHLDTVFT FADRDCVLIY PDIVDKIECF
     SYRPDGKGGV ELSRDKGLIE TVKEALGLKE IRVVETGGND YMRERTQWDS GANLVCASPG
     VVFAYDRNTY ANTLLRKAGI EVITIDGSEL GRGRGGGHCM TCPIIRDAVD F
//

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