(data stored in SCRATCH zone)

SWISSPROT: D7A0Z9_STAND

ID   D7A0Z9_STAND            Unreviewed;       329 AA.
AC   D7A0Z9;
DT   10-AUG-2010, integrated into UniProtKB/TrEMBL.
DT   10-AUG-2010, sequence version 1.
DT   08-MAY-2019, entry version 43.
DE   SubName: Full=D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding protein {ECO:0000313|EMBL:ADH87509.1};
GN   OrderedLocusNames=Snov_0173 {ECO:0000313|EMBL:ADH87509.1};
OS   Starkeya novella (strain ATCC 8093 / DSM 506 / CCM 1077 / IAM 12100 /
OS   NBRC 12443 / NCIB 9113).
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Rhizobiales;
OC   Xanthobacteraceae; Starkeya.
OX   NCBI_TaxID=639283 {ECO:0000313|EMBL:ADH87509.1, ECO:0000313|Proteomes:UP000006633};
RN   [1] {ECO:0000313|Proteomes:UP000006633}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 8093 / DSM 506 / CCM 1077 / IAM 12100 / NBRC 12443 / NCIB
RC   9113 {ECO:0000313|Proteomes:UP000006633};
RG   US DOE Joint Genome Institute;
RA   Lucas S., Copeland A., Lapidus A., Cheng J.-F., Bruce D., Goodwin L.,
RA   Pitluck S., Davenport K., Brettin T., Detter J.C., Han C., Tapia R.,
RA   Land M., Hauser L., Kyrpides N., Ivanova N., Beatson S., Kappler U.,
RA   Woyke T.;
RT   "Complete sequence of Starkeya novella DSM 506.";
RL   Submitted (MAY-2010) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EMBL:ADH87509.1, ECO:0000313|Proteomes:UP000006633}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 8093 / DSM 506 / CCM 1077 / IAM 12100 / NBRC 12443 / NCIB
RC   9113 {ECO:0000313|Proteomes:UP000006633};
RX   PubMed=23450099; DOI=10.4056/sigs.3006378;
RA   Kappler U., Davenport K., Beatson S., Lucas S., Lapidus A.,
RA   Copeland A., Berry K.W., Glavina Del Rio T., Hammon N., Dalin E.,
RA   Tice H., Pitluck S., Richardson P., Bruce D., Goodwin L.A., Han C.,
RA   Tapia R., Detter J.C., Chang Y.J., Jeffries C.D., Land M., Hauser L.,
RA   Kyrpides N.C., Goker M., Ivanova N., Klenk H.P., Woyke T.;
RT   "Complete genome sequence of the facultatively chemolithoautotrophic
RT   and methylotrophic alpha Proteobacterium Starkeya novella type strain
RT   (ATCC 8093(T)).";
RL   Stand. Genomic Sci. 7:44-58(2012).
CC   -!- SIMILARITY: Belongs to the D-isomer specific 2-hydroxyacid
CC       dehydrogenase family. {ECO:0000256|RuleBase:RU003719}.
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DR   EMBL; CP002026; ADH87509.1; -; Genomic_DNA.
DR   RefSeq; WP_013165014.1; NC_014217.1.
DR   STRING; 639283.Snov_0173; -.
DR   EnsemblBacteria; ADH87509; ADH87509; Snov_0173.
DR   KEGG; sno:Snov_0173; -.
DR   eggNOG; ENOG4108JQ1; Bacteria.
DR   eggNOG; COG0111; LUCA.
DR   HOGENOM; HOG000136700; -.
DR   KO; K00058; -.
DR   OMA; DHEVKVF; -.
DR   OrthoDB; 1638924at2; -.
DR   BioCyc; SNOV639283:G1GLM-175-MONOMER; -.
DR   Proteomes; UP000006633; Chromosome.
DR   GO; GO:0051287; F:NAD binding; IEA:InterPro.
DR   GO; GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IEA:InterPro.
DR   InterPro; IPR006139; D-isomer_2_OHA_DH_cat_dom.
DR   InterPro; IPR029753; D-isomer_DH_CS.
DR   InterPro; IPR006140; D-isomer_DH_NAD-bd.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   Pfam; PF00389; 2-Hacid_dh; 1.
DR   Pfam; PF02826; 2-Hacid_dh_C; 1.
DR   SUPFAM; SSF51735; SSF51735; 1.
DR   PROSITE; PS00670; D_2_HYDROXYACID_DH_2; 1.
DR   PROSITE; PS00671; D_2_HYDROXYACID_DH_3; 1.
PE   3: Inferred from homology;
DR   PRODOM; D7A0Z9.
DR   SWISS-2DPAGE; D7A0Z9.
KW   Complete proteome {ECO:0000313|Proteomes:UP000006633};
KW   Oxidoreductase {ECO:0000256|RuleBase:RU003719};
KW   Reference proteome {ECO:0000313|Proteomes:UP000006633}.
FT   DOMAIN        6    315       2-Hacid_dh. {ECO:0000259|Pfam:PF00389}.
FT   DOMAIN      106    283       2-Hacid_dh_C. {ECO:0000259|Pfam:PF02826}.
SQ   SEQUENCE   329 AA;  34120 MW;  84900AC90899C347 CRC64;
     MSSLCLILQR IHDAGVEHLL AAGHEVRLAT SLEPGALLAE IAPARAVLTR DARVDGPLMD
     AAPDLKVIGV HGAGVDNVDI AAATARGIPV VNTPGANARS VAEHALALAF HLAKALGPGE
     RAARASDGSF KYRARMIELD GAVFGLVGFG AIGRETGRLA RALGMEVIVW TRRPDDPAVA
     AAGFTHVADL NELLARADIV SLHLPGGAQT RHLIGAPELA RMKDTAYLIN TARGTIIDEA
     ALVEALREGR IAGAGLDVFE TEPMPPSSPL IGFDNVVLSP HVGGSTQAAL RRTAVALAEQ
     VNDVLAGRRP AHLVNPEVWP IAAIAEAGA
//

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