(data stored in SCRATCH zone)

SWISSPROT: D7A334_STAND

ID   D7A334_STAND            Unreviewed;       293 AA.
AC   D7A334;
DT   10-AUG-2010, integrated into UniProtKB/TrEMBL.
DT   10-AUG-2010, sequence version 1.
DT   08-MAY-2019, entry version 47.
DE   SubName: Full=3-hydroxyisobutyrate dehydrogenase {ECO:0000313|EMBL:ADH87752.1};
DE            EC=1.1.1.31 {ECO:0000313|EMBL:ADH87752.1};
GN   OrderedLocusNames=Snov_0419 {ECO:0000313|EMBL:ADH87752.1};
OS   Starkeya novella (strain ATCC 8093 / DSM 506 / CCM 1077 / IAM 12100 /
OS   NBRC 12443 / NCIB 9113).
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Rhizobiales;
OC   Xanthobacteraceae; Starkeya.
OX   NCBI_TaxID=639283 {ECO:0000313|EMBL:ADH87752.1, ECO:0000313|Proteomes:UP000006633};
RN   [1] {ECO:0000313|Proteomes:UP000006633}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 8093 / DSM 506 / CCM 1077 / IAM 12100 / NBRC 12443 / NCIB
RC   9113 {ECO:0000313|Proteomes:UP000006633};
RG   US DOE Joint Genome Institute;
RA   Lucas S., Copeland A., Lapidus A., Cheng J.-F., Bruce D., Goodwin L.,
RA   Pitluck S., Davenport K., Brettin T., Detter J.C., Han C., Tapia R.,
RA   Land M., Hauser L., Kyrpides N., Ivanova N., Beatson S., Kappler U.,
RA   Woyke T.;
RT   "Complete sequence of Starkeya novella DSM 506.";
RL   Submitted (MAY-2010) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EMBL:ADH87752.1, ECO:0000313|Proteomes:UP000006633}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 8093 / DSM 506 / CCM 1077 / IAM 12100 / NBRC 12443 / NCIB
RC   9113 {ECO:0000313|Proteomes:UP000006633};
RX   PubMed=23450099; DOI=10.4056/sigs.3006378;
RA   Kappler U., Davenport K., Beatson S., Lucas S., Lapidus A.,
RA   Copeland A., Berry K.W., Glavina Del Rio T., Hammon N., Dalin E.,
RA   Tice H., Pitluck S., Richardson P., Bruce D., Goodwin L.A., Han C.,
RA   Tapia R., Detter J.C., Chang Y.J., Jeffries C.D., Land M., Hauser L.,
RA   Kyrpides N.C., Goker M., Ivanova N., Klenk H.P., Woyke T.;
RT   "Complete genome sequence of the facultatively chemolithoautotrophic
RT   and methylotrophic alpha Proteobacterium Starkeya novella type strain
RT   (ATCC 8093(T)).";
RL   Stand. Genomic Sci. 7:44-58(2012).
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DR   EMBL; CP002026; ADH87752.1; -; Genomic_DNA.
DR   RefSeq; WP_013165257.1; NC_014217.1.
DR   STRING; 639283.Snov_0419; -.
DR   EnsemblBacteria; ADH87752; ADH87752; Snov_0419.
DR   KEGG; sno:Snov_0419; -.
DR   eggNOG; ENOG4106KE4; Bacteria.
DR   eggNOG; COG2084; LUCA.
DR   HOGENOM; HOG000219608; -.
DR   OMA; RYEPPGF; -.
DR   OrthoDB; 1194694at2; -.
DR   BioCyc; SNOV639283:G1GLM-424-MONOMER; -.
DR   Proteomes; UP000006633; Chromosome.
DR   GO; GO:0008442; F:3-hydroxyisobutyrate dehydrogenase activity; IEA:UniProtKB-EC.
DR   GO; GO:0051287; F:NAD binding; IEA:InterPro.
DR   GO; GO:0050661; F:NADP binding; IEA:InterPro.
DR   Gene3D; 1.10.1040.10; -; 1.
DR   InterPro; IPR002204; 3-OH-isobutyrate_DH-rel_CS.
DR   InterPro; IPR008927; 6-PGluconate_DH-like_C_sf.
DR   InterPro; IPR013328; 6PGD_dom2.
DR   InterPro; IPR006115; 6PGDH_NADP-bd.
DR   InterPro; IPR015815; HIBADH-related.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   InterPro; IPR029154; NADP-bd.
DR   Pfam; PF14833; NAD_binding_11; 1.
DR   Pfam; PF03446; NAD_binding_2; 1.
DR   PIRSF; PIRSF000103; HIBADH; 1.
DR   SUPFAM; SSF48179; SSF48179; 1.
DR   SUPFAM; SSF51735; SSF51735; 1.
DR   PROSITE; PS00895; 3_HYDROXYISOBUT_DH; 1.
PE   4: Predicted;
DR   PRODOM; D7A334.
DR   SWISS-2DPAGE; D7A334.
KW   Complete proteome {ECO:0000313|Proteomes:UP000006633};
KW   Oxidoreductase {ECO:0000313|EMBL:ADH87752.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000006633}.
FT   DOMAIN        2    157       NAD_binding_2. {ECO:0000259|Pfam:
FT                                PF03446}.
FT   DOMAIN      166    284       NAD_binding_11. {ECO:0000259|Pfam:
FT                                PF14833}.
FT   ACT_SITE    170    170       {ECO:0000256|PIRSR:PIRSR000103-1}.
SQ   SEQUENCE   293 AA;  29669 MW;  D962005A62F29DA0 CRC64;
     MKVGFIGLGS MGAGMARNLL KAGHEVTVFN RSPAKAAPLV EAGAVAASSV AEACKGEAVI
     TMLADDAAVS SVAEGEGGIL ASLAPGALHV SASTISVALS EKLTAAHAEA GQLYAAAPVF
     GRPEVAAAGE LFVAAAGPAD TLTLAQPLFD AIGRQTFVFS DTPSKANLVK LSGNFLIACV
     IETLGEALAL VGKGGVDQKQ YLDFLTSTLF GAPVYRNYGN LIVDTTPRPV GFAAPLGLKD
     MRLALAAAEE LRVPLPVGSL LRDRFLTLLA NGGEGQDWSA IGRLAAKDAG GVV
//

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