(data stored in ACNUC1104 zone)

SWISSPROT: D7C5I1_STRBB

ID   D7C5I1_STRBB            Unreviewed;       492 AA.
AC   D7C5I1;
DT   10-AUG-2010, integrated into UniProtKB/TrEMBL.
DT   10-AUG-2010, sequence version 1.
DT   08-MAY-2019, entry version 45.
DE   SubName: Full=Efflux protein {ECO:0000313|EMBL:ADI10369.1};
GN   OrderedLocusNames=SBI_07249 {ECO:0000313|EMBL:ADI10369.1};
OS   Streptomyces bingchenggensis (strain BCW-1).
OC   Bacteria; Actinobacteria; Streptomycetales; Streptomycetaceae;
OC   Streptomyces.
OX   NCBI_TaxID=749414 {ECO:0000313|EMBL:ADI10369.1, ECO:0000313|Proteomes:UP000000377};
RN   [1] {ECO:0000313|EMBL:ADI10369.1, ECO:0000313|Proteomes:UP000000377}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=BCW-1 {ECO:0000313|EMBL:ADI10369.1,
RC   ECO:0000313|Proteomes:UP000000377};
RX   PubMed=20581206; DOI=10.1128/JB.00596-10;
RA   Wang X.J., Yan Y.J., Zhang B., An J., Wang J.J., Tian J., Jiang L.,
RA   Chen Y.H., Huang S.X., Yin M., Zhang J., Gao A.L., Liu C.X., Zhu Z.X.,
RA   Xiang W.S.;
RT   "Genome sequence of the milbemycin-producing bacterium Streptomyces
RT   bingchenggensis.";
RL   J. Bacteriol. 192:4526-4527(2010).
CC   -!- SIMILARITY: Belongs to the major facilitator superfamily.
CC       {ECO:0000256|SAAS:SAAS00769108}.
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DR   EMBL; CP002047; ADI10369.1; -; Genomic_DNA.
DR   RefSeq; WP_014179819.1; NC_016582.1.
DR   STRING; 749414.SBI_07249; -.
DR   EnsemblBacteria; ADI10369; ADI10369; SBI_07249.
DR   KEGG; sbh:SBI_07249; -.
DR   PATRIC; fig|749414.3.peg.7463; -.
DR   eggNOG; ENOG4105C57; Bacteria.
DR   eggNOG; COG0477; LUCA.
DR   HOGENOM; HOG000239124; -.
DR   OMA; GNKKGWL; -.
DR   OrthoDB; 1108236at2; -.
DR   BioCyc; SBIN749414:G1GKW-7282-MONOMER; -.
DR   Proteomes; UP000000377; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR   GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR   CDD; cd06174; MFS; 1.
DR   InterPro; IPR004638; EmrB-like.
DR   InterPro; IPR011701; MFS.
DR   InterPro; IPR020846; MFS_dom.
DR   InterPro; IPR036259; MFS_trans_sf.
DR   Pfam; PF07690; MFS_1; 1.
DR   SUPFAM; SSF103473; SSF103473; 1.
DR   TIGRFAMs; TIGR00711; efflux_EmrB; 1.
DR   PROSITE; PS50850; MFS; 1.
PE   3: Inferred from homology;
DR   PRODOM; D7C5I1.
DR   SWISS-2DPAGE; D7C5I1.
KW   Cell membrane {ECO:0000256|SAAS:SAAS00769078};
KW   Complete proteome {ECO:0000313|Proteomes:UP000000377};
KW   Membrane {ECO:0000256|SAAS:SAAS00769060, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000000377};
KW   Transmembrane {ECO:0000256|SAAS:SAAS00769091,
KW   ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAAS:SAAS00769070,
KW   ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|SAAS:SAAS00769034}.
FT   TRANSMEM     47     66       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    137    156       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    168    188       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    200    218       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    224    247       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    268    290       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    302    319       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    331    350       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    356    377       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    407    431       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    443    467       Helical. {ECO:0000256|SAM:Phobius}.
FT   DOMAIN       12    466       MFS. {ECO:0000259|PROSITE:PS50850}.
SQ   SEQUENCE   492 AA;  50574 MW;  FE2C48040C456C57 CRC64;
     MPELSHRRRT LVLAICCMSL LLVSLDNTVL NVALPSMRRE LHASVSGMQW TIDAYTLVLA
     ALLMLAGSTA DRVGRKRTFQ TGLVVFSLGS ALCSLAPNLE ALVAFRMVQA VGGSMLNPVA
     MSIITNTFTE PKERARAIGV WGGVVGISMA AGPLVGGVLV QSVGWRSIFW LNVPVGLAAL
     VLTARYVPES RAPKPRRPDP VGQVLVAALL GTLTYAIIEA PDRGWGSPLI AVCTTVSALA
     LVSLVAYERR RTEPLVELRF FHSAPFSGAT VIAVSAFAAL GGFLFLNTLY LQDVRGLGAL
     HAGLWMLPMA AMCFVFAPLS GRLVGSRGPR LSLLLAGAAM GASGVLFAAF DAQATDALLL
     IGYVLFGIGF GLVNAPITNT AVSGMPRTQA GVAAAVASTS RQVGQSLGVA VIGAVLASGA
     ASAAGGAHSA ASATAFVDAA RPAWWIIAGC GGAVLLLGVA TTGRWAAGTA KRASALFGDE
     RAPAQASATT NA
//

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