(data stored in SCRATCH zone)

SWISSPROT: D9QTD4_ACEAZ

ID   D9QTD4_ACEAZ            Unreviewed;       398 AA.
AC   D9QTD4;
DT   05-OCT-2010, integrated into UniProtKB/TrEMBL.
DT   05-OCT-2010, sequence version 1.
DT   11-DEC-2019, entry version 61.
DE   RecName: Full=Elongation factor Tu {ECO:0000256|HAMAP-Rule:MF_00118, ECO:0000256|RuleBase:RU004061};
DE            Short=EF-Tu {ECO:0000256|HAMAP-Rule:MF_00118};
GN   Name=tuf {ECO:0000256|HAMAP-Rule:MF_00118};
GN   OrderedLocusNames=Acear_0147 {ECO:0000313|EMBL:ADL11698.1}, Acear_0160
GN   {ECO:0000313|EMBL:ADL11711.1};
OS   Acetohalobium arabaticum (strain ATCC 49924 / DSM 5501 / Z-7288).
OC   Bacteria; Firmicutes; Clostridia; Halanaerobiales; Halobacteroidaceae;
OC   Acetohalobium.
OX   NCBI_TaxID=574087 {ECO:0000313|EMBL:ADL11698.1, ECO:0000313|Proteomes:UP000001661};
RN   [1] {ECO:0000313|EMBL:ADL11698.1, ECO:0000313|Proteomes:UP000001661}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 49924 / DSM 5501 / Z-7288
RC   {ECO:0000313|Proteomes:UP000001661}, and DSM 5501
RC   {ECO:0000313|EMBL:ADL11698.1};
RX   PubMed=21304692;
RA   Sikorski J., Lapidus A., Chertkov O., Lucas S., Copeland A.,
RA   Glavina Del Rio T., Nolan M., Tice H., Cheng J.F., Han C., Brambilla E.,
RA   Pitluck S., Liolios K., Ivanova N., Mavromatis K., Mikhailova N., Pati A.,
RA   Bruce D., Detter C., Tapia R., Goodwin L., Chen A., Palaniappan K.,
RA   Land M., Hauser L., Chang Y.J., Jeffries C.D., Rohde M., Goker M.,
RA   Spring S., Woyke T., Bristow J., Eisen J.A., Markowitz V., Hugenholtz P.,
RA   Kyrpides N.C., Klenk H.P.;
RT   "Complete genome sequence of Acetohalobium arabaticum type strain (Z-
RT   7288).";
RL   Stand. Genomic Sci. 3:57-65(2010).
RN   [2] {ECO:0000313|EMBL:ADL11698.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=DSM 5501 {ECO:0000313|EMBL:ADL11698.1};
RG   US DOE Joint Genome Institute (JGI-PGF);
RA   Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E., Tice H.,
RA   Bruce D., Goodwin L., Pitluck S., Kyrpides N., Mavromatis K., Ivanova N.,
RA   Mikhailova N., Chertkov O., Brettin T., Detter J.C., Han C., Tapia R.,
RA   Larimer F., Land M., Hauser L., Markowitz V., Cheng J.-F., Hugenholtz P.,
RA   Woyke T., Wu D., Tindall B., Pomrenke H.G., Schneider S., Klenk H.-P.,
RA   Eisen J.A.;
RT   "The complete genome of Acetohalobium arabaticum DSM 5501.";
RL   Submitted (JUL-2010) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: This protein promotes the GTP-dependent binding of aminoacyl-
CC       tRNA to the A-site of ribosomes during protein biosynthesis.
CC       {ECO:0000256|HAMAP-Rule:MF_00118}.
CC   -!- SUBUNIT: Monomer. {ECO:0000256|HAMAP-Rule:MF_00118}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00118}.
CC   -!- SIMILARITY: Belongs to the TRAFAC class translation factor GTPase
CC       superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A
CC       subfamily. {ECO:0000256|HAMAP-Rule:MF_00118}.
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DR   EMBL; CP002105; ADL11698.1; -; Genomic_DNA.
DR   EMBL; CP002105; ADL11711.1; -; Genomic_DNA.
DR   RefSeq; WP_013277145.1; NC_014378.1.
DR   STRING; 574087.Acear_0160; -.
DR   EnsemblBacteria; ADL11698; ADL11698; Acear_0147.
DR   EnsemblBacteria; ADL11711; ADL11711; Acear_0160.
DR   KEGG; aar:Acear_0147; -.
DR   KEGG; aar:Acear_0160; -.
DR   eggNOG; ENOG4105CGV; Bacteria.
DR   eggNOG; COG0050; LUCA.
DR   HOGENOM; HOG000229290; -.
DR   KO; K02358; -.
DR   OMA; AIRDMGM; -.
DR   OrthoDB; 621774at2; -.
DR   BioCyc; AARA574087:G1GMC-174-MONOMER; -.
DR   BioCyc; AARA574087:G1GMC-187-MONOMER; -.
DR   Proteomes; UP000001661; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR   GO; GO:0003746; F:translation elongation factor activity; IEA:UniProtKB-UniRule.
DR   CDD; cd01884; EF_Tu; 1.
DR   CDD; cd03697; EFTU_II; 1.
DR   HAMAP; MF_00118_B; EF_Tu_B; 1.
DR   InterPro; IPR041709; EF-Tu_GTP-bd.
DR   InterPro; IPR004161; EFTu-like_2.
DR   InterPro; IPR033720; EFTU_2.
DR   InterPro; IPR031157; G_TR_CS.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR005225; Small_GTP-bd_dom.
DR   InterPro; IPR000795; TF_GTP-bd_dom.
DR   InterPro; IPR009000; Transl_B-barrel_sf.
DR   InterPro; IPR009001; Transl_elong_EF1A/Init_IF2_C.
DR   InterPro; IPR004541; Transl_elong_EFTu/EF1A_bac/org.
DR   InterPro; IPR004160; Transl_elong_EFTu/EF1A_C.
DR   Pfam; PF00009; GTP_EFTU; 1.
DR   Pfam; PF03144; GTP_EFTU_D2; 1.
DR   Pfam; PF03143; GTP_EFTU_D3; 1.
DR   PRINTS; PR00315; ELONGATNFCT.
DR   SUPFAM; SSF50447; SSF50447; 1.
DR   SUPFAM; SSF50465; SSF50465; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR00485; EF-Tu; 1.
DR   TIGRFAMs; TIGR00231; small_GTP; 1.
DR   PROSITE; PS00301; G_TR_1; 1.
DR   PROSITE; PS51722; G_TR_2; 1.
PE   3: Inferred from homology;
DR   PRODOM; D9QTD4.
DR   SWISS-2DPAGE; D9QTD4.
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00118};
KW   Elongation factor {ECO:0000256|HAMAP-Rule:MF_00118,
KW   ECO:0000313|EMBL:ADL11698.1};
KW   GTP-binding {ECO:0000256|HAMAP-Rule:MF_00118};
KW   Nucleotide-binding {ECO:0000256|HAMAP-Rule:MF_00118};
KW   Protein biosynthesis {ECO:0000256|HAMAP-Rule:MF_00118};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001661}.
FT   DOMAIN          10..208
FT                   /note="Tr-type G"
FT                   /evidence="ECO:0000259|PROSITE:PS51722"
FT   NP_BIND         19..26
FT                   /note="GTP"
FT                   /evidence="ECO:0000256|HAMAP-Rule:MF_00118"
FT   NP_BIND         80..84
FT                   /note="GTP"
FT                   /evidence="ECO:0000256|HAMAP-Rule:MF_00118"
FT   NP_BIND         135..138
FT                   /note="GTP"
FT                   /evidence="ECO:0000256|HAMAP-Rule:MF_00118"
FT   COILED          139..159
FT                   /evidence="ECO:0000256|SAM:Coils"
SQ   SEQUENCE   398 AA;  43870 MW;  95FB7611DDA2597A CRC64;
     MAKEKFERDK PHMNIGTIGH VDHGKTTTTA AITKVLSKGE EGSANFEDID NAPEEQERGI
     TIATSHVEYE TENRHYAHVD CPGHADYVKN MITGAAQMDG ALLVVSAADG PMPQTREHLL
     LARQVNVPNI VVFLNKADMV DDEELIELVE MEVRELLNEY DFNGDEVPII VGSGLKALEC
     GCGDRDCEWC GQILELMDAI DEYLPEPERD TDKPFLLPVE DVFTIKGRGT VATGRLERGK
     LHPGDEAELV GVKDTQETVV TGVEMFRKML DEAVAGDNIG ALLRGVDREE IERGQVLAEP
     GSITPHTEFE AEVYVLSKDE GGRHTPFFDG YRPQFYFRTT DVTGDINLPD DVEMVMPGDN
     VEMGVKLITP IAMEEGLRFA IREGGKTVGA GVITEIIE
//

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