(data stored in ACNUC1104 zone)

SWISSPROT: D9TA24_MICAI

ID   D9TA24_MICAI            Unreviewed;       540 AA.
AC   D9TA24;
DT   05-OCT-2010, integrated into UniProtKB/TrEMBL.
DT   05-OCT-2010, sequence version 1.
DT   08-MAY-2019, entry version 43.
DE   SubName: Full=Drug resistance transporter, EmrB/QacA subfamily {ECO:0000313|EMBL:ADL44390.1};
GN   OrderedLocusNames=Micau_0826 {ECO:0000313|EMBL:ADL44390.1};
OS   Micromonospora aurantiaca (strain ATCC 27029 / DSM 43813 / BCRC 12538
OS   / CBS 129.76 / JCM 10878 / NBRC 16125 / NRRL B-16091 / INA 9442).
OC   Bacteria; Actinobacteria; Micromonosporales; Micromonosporaceae;
OC   Micromonospora.
OX   NCBI_TaxID=644283 {ECO:0000313|EMBL:ADL44390.1, ECO:0000313|Proteomes:UP000001908};
RN   [1] {ECO:0000313|EMBL:ADL44390.1, ECO:0000313|Proteomes:UP000001908}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 27029 / DSM 43813 / JCM 10878 / NBRC 16125 / INA 9442
RC   {ECO:0000313|Proteomes:UP000001908};
RG   US DOE Joint Genome Institute;
RA   Lucas S., Copeland A., Lapidus A., Cheng J.-F., Bruce D., Goodwin L.,
RA   Pitluck S., Chertkov O., Detter J.C., Han C., Tapia R., Land M.,
RA   Hauser L., Chang Y.-J., Jeffries C., Kyrpides N., Ivanova N.,
RA   Ovchinnikova G., Hirsch A.M., Woyke T.;
RT   "Complete sequence of Micromonospora aurantiaca ATCC 27029.";
RL   Submitted (AUG-2010) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the major facilitator superfamily.
CC       {ECO:0000256|SAAS:SAAS00769108}.
CC   -----------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   -----------------------------------------------------------------------
DR   EMBL; CP002162; ADL44390.1; -; Genomic_DNA.
DR   RefSeq; WP_013284029.1; NC_014391.1.
DR   STRING; 644283.Micau_0826; -.
DR   EnsemblBacteria; ADL44390; ADL44390; Micau_0826.
DR   GeneID; 32161463; -.
DR   KEGG; mau:Micau_0826; -.
DR   eggNOG; ENOG4105C0R; Bacteria.
DR   eggNOG; ENOG410XNN3; LUCA.
DR   HOGENOM; HOG000239124; -.
DR   OMA; RWAFGIN; -.
DR   OrthoDB; 1108236at2; -.
DR   BioCyc; MAUR644283:MICAU_RS04120-MONOMER; -.
DR   Proteomes; UP000001908; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR   GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR   CDD; cd06174; MFS; 1.
DR   InterPro; IPR004638; EmrB-like.
DR   InterPro; IPR011701; MFS.
DR   InterPro; IPR020846; MFS_dom.
DR   InterPro; IPR036259; MFS_trans_sf.
DR   Pfam; PF07690; MFS_1; 1.
DR   SUPFAM; SSF103473; SSF103473; 1.
DR   TIGRFAMs; TIGR00711; efflux_EmrB; 1.
DR   PROSITE; PS50850; MFS; 1.
PE   3: Inferred from homology;
DR   PRODOM; D9TA24.
DR   SWISS-2DPAGE; D9TA24.
KW   Cell membrane {ECO:0000256|SAAS:SAAS00769078};
KW   Complete proteome {ECO:0000313|Proteomes:UP000001908};
KW   Membrane {ECO:0000256|SAAS:SAAS00769060, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001908};
KW   Transmembrane {ECO:0000256|SAAS:SAAS00769091,
KW   ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAAS:SAAS00769070,
KW   ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|SAAS:SAAS00769034}.
FT   TRANSMEM     12     33       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM     53     70       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM     77     96       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    102    123       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    135    157       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    163    185       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    197    218       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    238    261       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    289    310       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    322    342       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    354    371       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    377    402       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    423    444       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    500    519       Helical. {ECO:0000256|SAM:Phobius}.
FT   DOMAIN       11    524       MFS. {ECO:0000259|PROSITE:PS50850}.
SQ   SEQUENCE   540 AA;  56014 MW;  80BA46F35BED65FC CRC64;
     MRGDGRGRWF GLLAISLGVA MIIVDATIVN VAVPQIIRDL DITSTDAQWV QEAYTLVFAA
     LLLVAGRFAD RSGRRRMFLV GVTVFVVASV LAALAGSGET LIASRVLQGV GGAMMLPTSL
     SLLNANFTGR EKGIAFAVWG STIGGAAALG PLLGGWLTTT YSWRWAFGIN VPVGLAVIVA
     TLVLVAESRD ERAERGLDLL GALLSVVGMT GVVFALIEGR TYGWWERERP LRLFGLDWTA
     SISPVPVAAL VGLVALGIFL AQQVRRNRAG RPALLDLSLF GIGSFRNGIL AAAIVSLGEF
     GLLFALPLWF QNVLGYSAFR TGLALLPLAV GSFLASGIGA PLTQRWGAAR VVQLGVAAEL
     VGVAGLGFVV APDTSWWAPL GFLFVYGVGV GLATAQLTGV SLSQVPVRLS GQGSGLQSTA
     RQVGSALGIA VLGTVLFAGL GGILGDRLAD QPGLTPVQRD QVVSAVKESA GAAITGLAAD
     PRTAPIAEEA KQAFSDATRY AAFAGAGFLL IGLVACLRLP TVRHEETGEP PPAEAEPSRA
//

If you have problems or comments...

PBIL Back to PBIL home page