(data stored in SCRATCH zone)

SWISSPROT: E3J4Q5_FRAIE

ID   E3J4Q5_FRAIE            Unreviewed;       539 AA.
AC   E3J4Q5;
DT   11-JAN-2011, integrated into UniProtKB/TrEMBL.
DT   11-JAN-2011, sequence version 1.
DT   16-JAN-2019, entry version 46.
DE   RecName: Full=60 kDa chaperonin {ECO:0000256|HAMAP-Rule:MF_00600, ECO:0000256|RuleBase:RU000419};
DE   AltName: Full=GroEL protein {ECO:0000256|HAMAP-Rule:MF_00600};
DE   AltName: Full=Protein Cpn60 {ECO:0000256|HAMAP-Rule:MF_00600};
GN   Name=groL {ECO:0000256|HAMAP-Rule:MF_00600};
GN   Synonyms=groEL {ECO:0000256|HAMAP-Rule:MF_00600};
GN   OrderedLocusNames=FraEuI1c_0136 {ECO:0000313|EMBL:ADP78224.1};
OS   Frankia inefficax (strain DSM 45817 / CECT 9037 / EuI1c).
OC   Bacteria; Actinobacteria; Frankiales; Frankiaceae; Frankia.
OX   NCBI_TaxID=298654 {ECO:0000313|EMBL:ADP78224.1, ECO:0000313|Proteomes:UP000002484};
RN   [1] {ECO:0000313|EMBL:ADP78224.1, ECO:0000313|Proteomes:UP000002484}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 45817 / CECT 9037 / EuI1c
RC   {ECO:0000313|Proteomes:UP000002484};
RG   US DOE Joint Genome Institute;
RA   Lucas S., Copeland A., Lapidus A., Cheng J.-F., Bruce D., Goodwin L.,
RA   Pitluck S., Chertkov O., Detter J.C., Han C., Tapia R., Land M.,
RA   Hauser L., Jeffries C., Kyrpides N., Ivanova N., Mikhailova N.,
RA   Beauchemin N., Sen A., Sur S.A., Gtari M., Wall L., Tisa L., Woyke T.;
RT   "Complete sequence of Frankia sp. EuI1c.";
RL   Submitted (OCT-2010) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Prevents misfolding and promotes the refolding and
CC       proper assembly of unfolded polypeptides generated under stress
CC       conditions. {ECO:0000256|HAMAP-Rule:MF_00600,
CC       ECO:0000256|RuleBase:RU000419}.
CC   -!- SUBUNIT: Oligomer of 14 subunits composed of two stacked rings of
CC       7 subunits. {ECO:0000256|HAMAP-Rule:MF_00600,
CC       ECO:0000256|RuleBase:RU000419}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00600}.
CC   -!- SIMILARITY: Belongs to the chaperonin (HSP60) family.
CC       {ECO:0000256|HAMAP-Rule:MF_00600, ECO:0000256|RuleBase:RU000418}.
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DR   EMBL; CP002299; ADP78224.1; -; Genomic_DNA.
DR   RefSeq; WP_013421347.1; NC_014666.1.
DR   STRING; 298654.FraEuI1c_0136; -.
DR   EnsemblBacteria; ADP78224; ADP78224; FraEuI1c_0136.
DR   KEGG; fri:FraEuI1c_0136; -.
DR   eggNOG; ENOG4105CJ9; Bacteria.
DR   eggNOG; COG0459; LUCA.
DR   HOGENOM; HOG000076290; -.
DR   KO; K04077; -.
DR   OMA; TDTDKME; -.
DR   OrthoDB; 265347at2; -.
DR   BioCyc; FSP298654:G1GOT-139-MONOMER; -.
DR   Proteomes; UP000002484; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0051082; F:unfolded protein binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0042026; P:protein refolding; IEA:UniProtKB-UniRule.
DR   CDD; cd03344; GroEL; 1.
DR   Gene3D; 1.10.560.10; -; 1.
DR   Gene3D; 3.30.260.10; -; 1.
DR   Gene3D; 3.50.7.10; -; 1.
DR   HAMAP; MF_00600; CH60; 1.
DR   InterPro; IPR018370; Chaperonin_Cpn60_CS.
DR   InterPro; IPR001844; Chaprnin_Cpn60.
DR   InterPro; IPR002423; Cpn60/TCP-1.
DR   InterPro; IPR027409; GroEL-like_apical_dom_sf.
DR   InterPro; IPR027413; GROEL-like_equatorial_sf.
DR   InterPro; IPR027410; TCP-1-like_intermed_sf.
DR   Pfam; PF00118; Cpn60_TCP1; 1.
DR   PRINTS; PR00298; CHAPERONIN60.
DR   SUPFAM; SSF48592; SSF48592; 1.
DR   SUPFAM; SSF52029; SSF52029; 1.
DR   SUPFAM; SSF54849; SSF54849; 1.
DR   TIGRFAMs; TIGR02348; GroEL; 1.
DR   PROSITE; PS00296; CHAPERONINS_CPN60; 1.
PE   3: Inferred from homology;
DR   PRODOM; E3J4Q5.
DR   SWISS-2DPAGE; E3J4Q5.
KW   ATP-binding {ECO:0000256|HAMAP-Rule:MF_00600};
KW   Chaperone {ECO:0000256|HAMAP-Rule:MF_00600};
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Complete proteome {ECO:0000313|Proteomes:UP000002484};
KW   Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00600};
KW   Nucleotide-binding {ECO:0000256|HAMAP-Rule:MF_00600};
KW   Reference proteome {ECO:0000313|Proteomes:UP000002484}.
FT   COILED      123    143       {ECO:0000256|SAM:Coils}.
FT   COILED      387    407       {ECO:0000256|SAM:Coils}.
SQ   SEQUENCE   539 AA;  56733 MW;  4445FA3D9BB353BC CRC64;
     MPKIIAFDEE ARRGLERGMN QLADAVKVTL GPKGRNVVLE KKWGVPTITN DGVSIAKEIE
     LEDPYEKIGA ELVKEVAKKT NDVAGDGTTT ATILAQALVR EGLRNVAAGA NPLGLKKGIE
     LAVESVSEEL SKQAKEIETK EQIASTASIS AGDPAIGALI AEALDKVGKE GVVTVEESNT
     FGLELELTEG MRFDKGYISP YFVTDADRQE AVLDDPYILI VNSKISAVKD LLPLLEKVMQ
     ASKPLVIISE DVEGEALATL VVNKIRGTFK SVAVKAPGFG DRRKAMLGDI AILTGGQVIS
     EDVGLKLEST SIDLLGKARK VVVTKDETTI VEGAGDADQI TGRVSQIRNE IDKSDSDYDR
     EKLQERLAKL AGGVAVVKVG AATEVELKEK KHRIEDAVSN AKAAVEEGIV AGGGVALLQA
     SVSAFDKLDL TGDEATGANI VRLALEAPIK QIAFNSGLEG GVVVDKVRNL PIGHGLNAAT
     GEYVDMLATG IIDPAKVTRS ALQNAASIAG LFLTTEAVIA DKPEKNPAPA MPGGGDMDF
//

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