(data stored in SCRATCH zone)

SWISSPROT: E3J9X7_FRAIE

ID   E3J9X7_FRAIE            Unreviewed;       518 AA.
AC   E3J9X7;
DT   11-JAN-2011, integrated into UniProtKB/TrEMBL.
DT   11-JAN-2011, sequence version 1.
DT   08-MAY-2019, entry version 43.
DE   SubName: Full=Drug resistance transporter, EmrB/QacA subfamily {ECO:0000313|EMBL:ADP78539.1};
GN   OrderedLocusNames=FraEuI1c_0456 {ECO:0000313|EMBL:ADP78539.1};
OS   Frankia inefficax (strain DSM 45817 / CECT 9037 / EuI1c).
OC   Bacteria; Actinobacteria; Frankiales; Frankiaceae; Frankia.
OX   NCBI_TaxID=298654 {ECO:0000313|EMBL:ADP78539.1, ECO:0000313|Proteomes:UP000002484};
RN   [1] {ECO:0000313|EMBL:ADP78539.1, ECO:0000313|Proteomes:UP000002484}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 45817 / CECT 9037 / EuI1c
RC   {ECO:0000313|Proteomes:UP000002484};
RG   US DOE Joint Genome Institute;
RA   Lucas S., Copeland A., Lapidus A., Cheng J.-F., Bruce D., Goodwin L.,
RA   Pitluck S., Chertkov O., Detter J.C., Han C., Tapia R., Land M.,
RA   Hauser L., Jeffries C., Kyrpides N., Ivanova N., Mikhailova N.,
RA   Beauchemin N., Sen A., Sur S.A., Gtari M., Wall L., Tisa L., Woyke T.;
RT   "Complete sequence of Frankia sp. EuI1c.";
RL   Submitted (OCT-2010) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the major facilitator superfamily.
CC       {ECO:0000256|SAAS:SAAS00769108}.
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DR   EMBL; CP002299; ADP78539.1; -; Genomic_DNA.
DR   STRING; 298654.FraEuI1c_0456; -.
DR   EnsemblBacteria; ADP78539; ADP78539; FraEuI1c_0456.
DR   KEGG; fri:FraEuI1c_0456; -.
DR   eggNOG; ENOG4105C57; Bacteria.
DR   eggNOG; COG0477; LUCA.
DR   HOGENOM; HOG000239124; -.
DR   OMA; CWIACAL; -.
DR   BioCyc; FSP298654:G1GOT-454-MONOMER; -.
DR   Proteomes; UP000002484; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR   GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR   CDD; cd06174; MFS; 1.
DR   InterPro; IPR004638; EmrB-like.
DR   InterPro; IPR011701; MFS.
DR   InterPro; IPR020846; MFS_dom.
DR   InterPro; IPR036259; MFS_trans_sf.
DR   Pfam; PF07690; MFS_1; 1.
DR   SUPFAM; SSF103473; SSF103473; 1.
DR   TIGRFAMs; TIGR00711; efflux_EmrB; 1.
DR   PROSITE; PS50850; MFS; 1.
PE   3: Inferred from homology;
DR   PRODOM; E3J9X7.
DR   SWISS-2DPAGE; E3J9X7.
KW   Cell membrane {ECO:0000256|SAAS:SAAS00769078};
KW   Complete proteome {ECO:0000313|Proteomes:UP000002484};
KW   Membrane {ECO:0000256|SAAS:SAAS00769060, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000002484};
KW   Signal {ECO:0000256|SAM:SignalP};
KW   Transmembrane {ECO:0000256|SAAS:SAAS00769091,
KW   ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAAS:SAAS00769070,
KW   ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|SAAS:SAAS00769034}.
FT   SIGNAL        1     22       {ECO:0000256|SAM:SignalP}.
FT   CHAIN        23    518       {ECO:0000256|SAM:SignalP}.
FT                                /FTId=PRO_5003172740.
FT   TRANSMEM     49     66       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM     78     95       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    107    128       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    140    161       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    167    188       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    200    218       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    224    247       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    268    291       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    303    324       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    331    349       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    474    495       Helical. {ECO:0000256|SAM:Phobius}.
FT   DOMAIN       12    500       MFS. {ECO:0000259|PROSITE:PS50850}.
SQ   SEQUENCE   518 AA;  52639 MW;  1C5D67852063EC18 CRC64;
     MPSMSPRRRL AVLVTVCLAV FAINLDTTIV NVALPDLARQ LGATTRDLQW IVDGYNLAFA
     ALVLTAGSIG DRFGRRPVLL GGLVGFALMS GIGALCDGAG ALVAVRFVMG AFAALIFPTT
     LSIITNAYPD RAERAKAIGV WGAVTGLGVA IGPVTGGLLL AHFWWGSVFV ALVPVALVAA
     VLAFVLVPES SDPAAARLDL PGLVTSSAAI GLLVYTIIEA PDRGWTSALT LGGFAVTAAV
     AAAFVMLERR HPAPMLDVSL FRTPAFSAAS GAVTVAFFAL FGFIFLITQY FQFIRGFGTV
     STGVRILPVA LTIALGSVTG TLLAGRLGTR TIVVTGLVLF GGSFAWIAVS STYQPYLQIA
     AQMVLMGTGL GLTTAPATES ILSVLPAAKA GVGSAVNDAT REAGGTLGVA VIGSVFTSIY
     THHLAGTAVA ALPAQAANAA RDSVGAAFQV ASQAGPALRD QLVSDVNASF MSGLHIACFV
     AAGVCWLGAL GALALPGRRG MHAPQAEPAV APEAAAAV
//

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