(data stored in SCRATCH zone)

SWISSPROT: E6S6R8_INTC7

ID   E6S6R8_INTC7            Unreviewed;       372 AA.
AC   E6S6R8;
DT   08-MAR-2011, integrated into UniProtKB/TrEMBL.
DT   08-MAR-2011, sequence version 1.
DT   08-MAY-2019, entry version 47.
DE   RecName: Full=Putative phenylalanine aminotransferase {ECO:0000256|HAMAP-Rule:MF_01513};
DE            EC=2.6.1.- {ECO:0000256|HAMAP-Rule:MF_01513};
GN   Name=pat {ECO:0000256|HAMAP-Rule:MF_01513};
GN   OrderedLocusNames=Intca_0247 {ECO:0000313|EMBL:ADU46804.1};
OS   Intrasporangium calvum (strain ATCC 23552 / DSM 43043 / JCM 3097 /
OS   NBRC 12989 / 7 KIP).
OC   Bacteria; Actinobacteria; Micrococcales; Intrasporangiaceae;
OC   Intrasporangium.
OX   NCBI_TaxID=710696 {ECO:0000313|EMBL:ADU46804.1, ECO:0000313|Proteomes:UP000008914};
RN   [1] {ECO:0000313|EMBL:ADU46804.1, ECO:0000313|Proteomes:UP000008914}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 23552 / DSM 43043 / JCM 3097 / NBRC 12989 / 7 KIP
RC   {ECO:0000313|Proteomes:UP000008914};
RX   PubMed=21304734; DOI=10.4056/sigs.1263355;
RA   Del Rio T.G., Chertkov O., Yasawong M., Lucas S., Deshpande S.,
RA   Cheng J.F., Detter C., Tapia R., Han C., Goodwin L., Pitluck S.,
RA   Liolios K., Ivanova N., Mavromatis K., Pati A., Chen A.,
RA   Palaniappan K., Land M., Hauser L., Chang Y.J., Jeffries C.D.,
RA   Rohde M., Pukall R., Sikorski J., Goker M., Woyke T., Bristow J.,
RA   Eisen J.A., Markowitz V., Hugenholtz P., Kyrpides N.C., Klenk H.P.,
RA   Lapidus A.;
RT   "Complete genome sequence of Intrasporangium calvum type strain (7
RT   KIP).";
RL   Stand. Genomic Sci. 3:294-303(2010).
CC   -!- FUNCTION: May catalyze the transamination reaction in
CC       phenylalanine biosynthesis. {ECO:0000256|HAMAP-Rule:MF_01513}.
CC   -!- COFACTOR:
CC       Name=pyridoxal 5'-phosphate; Xref=ChEBI:CHEBI:597326;
CC         Evidence={ECO:0000256|HAMAP-Rule:MF_01513,
CC         ECO:0000256|SAAS:SAAS00612749};
CC   -!- SIMILARITY: Belongs to the class-II pyridoxal-phosphate-dependent
CC       aminotransferase family. {ECO:0000256|HAMAP-Rule:MF_01513}.
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DR   EMBL; CP002343; ADU46804.1; -; Genomic_DNA.
DR   RefSeq; WP_013491126.1; NC_014830.1.
DR   STRING; 710696.Intca_0247; -.
DR   EnsemblBacteria; ADU46804; ADU46804; Intca_0247.
DR   KEGG; ica:Intca_0247; -.
DR   eggNOG; ENOG4105CIH; Bacteria.
DR   eggNOG; COG0079; LUCA.
DR   HOGENOM; HOG000288510; -.
DR   KO; K00817; -.
DR   OrthoDB; 1248286at2; -.
DR   Proteomes; UP000008914; Chromosome.
DR   GO; GO:0004400; F:histidinol-phosphate transaminase activity; IEA:InterPro.
DR   GO; GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
DR   GO; GO:0000105; P:histidine biosynthetic process; IEA:InterPro.
DR   Gene3D; 3.40.640.10; -; 1.
DR   Gene3D; 3.90.1150.10; -; 1.
DR   HAMAP; MF_01023; HisC_aminotrans_2; 1.
DR   HAMAP; MF_01513; Phe_aminotrans_2; 1.
DR   InterPro; IPR001917; Aminotrans_II_pyridoxalP_BS.
DR   InterPro; IPR004839; Aminotransferase_I/II.
DR   InterPro; IPR005861; HisP_aminotrans.
DR   InterPro; IPR024892; Pat.
DR   InterPro; IPR015424; PyrdxlP-dep_Trfase.
DR   InterPro; IPR015422; PyrdxlP-dep_Trfase_dom1.
DR   InterPro; IPR015421; PyrdxlP-dep_Trfase_major.
DR   Pfam; PF00155; Aminotran_1_2; 1.
DR   SUPFAM; SSF53383; SSF53383; 1.
DR   TIGRFAMs; TIGR01141; hisC; 1.
DR   PROSITE; PS00599; AA_TRANSFER_CLASS_2; 1.
PE   3: Inferred from homology;
DR   PRODOM; E6S6R8.
DR   SWISS-2DPAGE; E6S6R8.
KW   Aminotransferase {ECO:0000256|HAMAP-Rule:MF_01513,
KW   ECO:0000256|SAAS:SAAS00458699, ECO:0000313|EMBL:ADU46804.1};
KW   Complete proteome {ECO:0000313|Proteomes:UP000008914};
KW   Pyridoxal phosphate {ECO:0000256|HAMAP-Rule:MF_01513,
KW   ECO:0000256|SAAS:SAAS00473492};
KW   Reference proteome {ECO:0000313|Proteomes:UP000008914};
KW   Transferase {ECO:0000256|HAMAP-Rule:MF_01513,
KW   ECO:0000256|SAAS:SAAS00458799, ECO:0000313|EMBL:ADU46804.1}.
FT   DOMAIN       46    343       Aminotran_1_2. {ECO:0000259|Pfam:
FT                                PF00155}.
FT   MOD_RES     237    237       N6-(pyridoxal phosphate)lysine.
FT                                {ECO:0000256|HAMAP-Rule:MF_01513}.
SQ   SEQUENCE   372 AA;  39580 MW;  C0637212D1F0777F CRC64;
     MSDDAVQPPP ATPGASPTVR LRQVLGQMPD YKPGRPAAAA AGVTPFKLSS NENPYGPLPS
     VLAAITEAAG SVNRYPDMAV VGLRERLGRA LSVSSDCIAT GTGSVAVLAQ IVQAACDAGD
     EVVFAWRSFE AYPIVTQLAG ATPVMVALDD RARHRLDAMA DAVTERTRVV LVCTPNNPTG
     PTVHRAELDA FLDRVPSDVI VVIDEAYVEF VRDPEAVRGL EVWRERPNVV VLRTFSKAYG
     LAGLRVGFAV AHPDVAAAIR KTATPFGVNS LAQVAAVASL DAFDELNERV ESIVAERERV
     VRALQDQGWK LPDSDANFVW FPLGSDSTAF AEACEAAGLM VRQYGDDGVR VTIGEAEANS
     RLLEVAEAFG AR
//

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