(data stored in SCRATCH zone)

SWISSPROT: E6S6W3_INTC7

ID   E6S6W3_INTC7            Unreviewed;       507 AA.
AC   E6S6W3;
DT   08-MAR-2011, integrated into UniProtKB/TrEMBL.
DT   08-MAR-2011, sequence version 1.
DT   08-MAY-2019, entry version 37.
DE   SubName: Full=Aldehyde Dehydrogenase {ECO:0000313|EMBL:ADU46849.1};
DE            EC=1.2.1.3 {ECO:0000313|EMBL:ADU46849.1};
GN   OrderedLocusNames=Intca_0294 {ECO:0000313|EMBL:ADU46849.1};
OS   Intrasporangium calvum (strain ATCC 23552 / DSM 43043 / JCM 3097 /
OS   NBRC 12989 / 7 KIP).
OC   Bacteria; Actinobacteria; Micrococcales; Intrasporangiaceae;
OC   Intrasporangium.
OX   NCBI_TaxID=710696 {ECO:0000313|EMBL:ADU46849.1, ECO:0000313|Proteomes:UP000008914};
RN   [1] {ECO:0000313|EMBL:ADU46849.1, ECO:0000313|Proteomes:UP000008914}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 23552 / DSM 43043 / JCM 3097 / NBRC 12989 / 7 KIP
RC   {ECO:0000313|Proteomes:UP000008914};
RX   PubMed=21304734; DOI=10.4056/sigs.1263355;
RA   Del Rio T.G., Chertkov O., Yasawong M., Lucas S., Deshpande S.,
RA   Cheng J.F., Detter C., Tapia R., Han C., Goodwin L., Pitluck S.,
RA   Liolios K., Ivanova N., Mavromatis K., Pati A., Chen A.,
RA   Palaniappan K., Land M., Hauser L., Chang Y.J., Jeffries C.D.,
RA   Rohde M., Pukall R., Sikorski J., Goker M., Woyke T., Bristow J.,
RA   Eisen J.A., Markowitz V., Hugenholtz P., Kyrpides N.C., Klenk H.P.,
RA   Lapidus A.;
RT   "Complete genome sequence of Intrasporangium calvum type strain (7
RT   KIP).";
RL   Stand. Genomic Sci. 3:294-303(2010).
CC   -!- SIMILARITY: Belongs to the aldehyde dehydrogenase family.
CC       {ECO:0000256|RuleBase:RU003345}.
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DR   EMBL; CP002343; ADU46849.1; -; Genomic_DNA.
DR   RefSeq; WP_013491171.1; NC_014830.1.
DR   STRING; 710696.Intca_0294; -.
DR   EnsemblBacteria; ADU46849; ADU46849; Intca_0294.
DR   KEGG; ica:Intca_0294; -.
DR   eggNOG; ENOG4105C26; Bacteria.
DR   eggNOG; COG1012; LUCA.
DR   HOGENOM; HOG000271505; -.
DR   KO; K00138; -.
DR   OrthoDB; 744602at2; -.
DR   BioCyc; ICAL710696:GH9U-300-MONOMER; -.
DR   Proteomes; UP000008914; Chromosome.
DR   GO; GO:0004029; F:aldehyde dehydrogenase (NAD) activity; IEA:UniProtKB-EC.
DR   GO; GO:0043878; F:glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity; IEA:UniProtKB-EC.
DR   Gene3D; 3.40.309.10; -; 1.
DR   Gene3D; 3.40.605.10; -; 1.
DR   InterPro; IPR016161; Ald_DH/histidinol_DH.
DR   InterPro; IPR016163; Ald_DH_C.
DR   InterPro; IPR016160; Ald_DH_CS_CYS.
DR   InterPro; IPR029510; Ald_DH_CS_GLU.
DR   InterPro; IPR016162; Ald_DH_N.
DR   InterPro; IPR015590; Aldehyde_DH_dom.
DR   Pfam; PF00171; Aldedh; 1.
DR   SUPFAM; SSF53720; SSF53720; 1.
DR   PROSITE; PS00070; ALDEHYDE_DEHYDR_CYS; 1.
DR   PROSITE; PS00687; ALDEHYDE_DEHYDR_GLU; 1.
PE   3: Inferred from homology;
DR   PRODOM; E6S6W3.
DR   SWISS-2DPAGE; E6S6W3.
KW   Complete proteome {ECO:0000313|Proteomes:UP000008914};
KW   Oxidoreductase {ECO:0000256|RuleBase:RU003345,
KW   ECO:0000313|EMBL:ADU46849.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000008914}.
FT   DOMAIN       28    494       Aldedh. {ECO:0000259|Pfam:PF00171}.
FT   ACT_SITE    263    263       {ECO:0000256|PROSITE-ProRule:PRU10007}.
FT   ACT_SITE    302    302       {ECO:0000256|PROSITE-ProRule:PRU10008}.
SQ   SEQUENCE   507 AA;  55071 MW;  80185BDA8DEFFD0F CRC64;
     MTIYAPPGSA DSLVSVEPRY GHFIGGNWVE PKKGEYFENI SPVTGRAFCE VGRGTEEDIE
     AALDAAHAAA PAWGRTSLGD RSLILNRIAD RIEENLEMLA VAETWENGKA VRETLAADLP
     LAVDHFRYFA GVLRGQEGSS SEIDENTVAY HFHEPLGVVG QIIPWNFPIL MAVWKLAPAL
     AAGNCVVLKP AEQTPWSILK VVELIGDLLP AGVLNVVNGF GVEAGKPLAS SPRIAKIAFT
     GETTTGRLIM QYASQNIIPV TLELGGKSPN VFFDDVAQER DAFYDKALEG FTMFALNQGE
     VCTCPSRALV QRSIYADFVP DAIARVEKIV QGNPLDTTTT MGAQASNDQL EKILSYIDIG
     RQEGAKVLTG GERNVLDGDL AGGYYVTPTV FEGSNSMRIF QEEIFGPVLS LTGFDDEADA
     LSIANDTLYG LGAGVWTRDG SRAYRMGRGI KAGRVWTNCY HQYPAHAAFG GYKQSGIGRE
     NHKMMLDHYQ QTKNLLVSYS PDALGFF
//

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