(data stored in SCRATCH zone)

SWISSPROT: E6V2E6_VARPE

ID   E6V2E6_VARPE            Unreviewed;       376 AA.
AC   E6V2E6;
DT   08-MAR-2011, integrated into UniProtKB/TrEMBL.
DT   08-MAR-2011, sequence version 1.
DT   08-MAY-2019, entry version 51.
DE   SubName: Full=Alcohol dehydrogenase zinc-binding domain protein {ECO:0000313|EMBL:ADU34577.1};
GN   OrderedLocusNames=Varpa_0355 {ECO:0000313|EMBL:ADU34577.1};
OS   Variovorax paradoxus (strain EPS).
OC   Bacteria; Proteobacteria; Betaproteobacteria; Burkholderiales;
OC   Comamonadaceae; Variovorax.
OX   NCBI_TaxID=595537 {ECO:0000313|EMBL:ADU34577.1, ECO:0000313|Proteomes:UP000008917};
RN   [1] {ECO:0000313|Proteomes:UP000008917}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=EPS {ECO:0000313|Proteomes:UP000008917};
RG   US DOE Joint Genome Institute;
RA   Lucas S., Copeland A., Lapidus A., Cheng J.-F., Goodwin L.,
RA   Pitluck S., Teshima H., Detter J.C., Han C., Tapia R., Land M.,
RA   Hauser L., Kyrpides N., Ivanova N., Ovchinnikova G., Orwin P.,
RA   Han J.-I.G., Woyke T.;
RT   "Complete sequence of Variovorax paradoxus EPS.";
RL   Submitted (DEC-2010) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EMBL:ADU34577.1, ECO:0000313|Proteomes:UP000008917}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=EPS {ECO:0000313|EMBL:ADU34577.1,
RC   ECO:0000313|Proteomes:UP000008917};
RX   PubMed=24158554;
RA   Han J.I., Spain J.C., Leadbetter J.R., Ovchinnikova G., Goodwin L.A.,
RA   Han C.S., Woyke T., Davenport K.W., Orwin P.M.;
RT   "Genome of the Root-Associated Plant Growth-Promoting Bacterium
RT   Variovorax paradoxus Strain EPS.";
RL   Genome Announc. 1:e00843-13(2013).
CC   -!- COFACTOR:
CC       Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC         Evidence={ECO:0000256|RuleBase:RU361277};
CC   -!- SIMILARITY: Belongs to the zinc-containing alcohol dehydrogenase
CC       family. {ECO:0000256|RuleBase:RU361277}.
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DR   EMBL; CP002417; ADU34577.1; -; Genomic_DNA.
DR   RefSeq; WP_013538823.1; NC_014931.1.
DR   STRING; 595537.Varpa_0355; -.
DR   EnsemblBacteria; ADU34577; ADU34577; Varpa_0355.
DR   GeneID; 29719813; -.
DR   KEGG; vpe:Varpa_0355; -.
DR   eggNOG; ENOG4105CPQ; Bacteria.
DR   eggNOG; COG1063; LUCA.
DR   HOGENOM; HOG000294686; -.
DR   KO; K00008; -.
DR   OMA; CKCHSGA; -.
DR   OrthoDB; 972769at2; -.
DR   BioCyc; VPAR595537:G1GQO-357-MONOMER; -.
DR   Proteomes; UP000008917; Chromosome.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   InterPro; IPR013149; ADH_C.
DR   InterPro; IPR013154; ADH_N.
DR   InterPro; IPR002328; ADH_Zn_CS.
DR   InterPro; IPR011032; GroES-like_sf.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   InterPro; IPR020843; PKS_ER.
DR   Pfam; PF08240; ADH_N; 1.
DR   Pfam; PF00107; ADH_zinc_N; 1.
DR   SMART; SM00829; PKS_ER; 1.
DR   SUPFAM; SSF50129; SSF50129; 1.
DR   SUPFAM; SSF51735; SSF51735; 1.
DR   PROSITE; PS00059; ADH_ZINC; 1.
PE   3: Inferred from homology;
DR   PRODOM; E6V2E6.
DR   SWISS-2DPAGE; E6V2E6.
KW   Complete proteome {ECO:0000313|Proteomes:UP000008917};
KW   Metal-binding {ECO:0000256|RuleBase:RU361277};
KW   Reference proteome {ECO:0000313|Proteomes:UP000008917};
KW   Zinc {ECO:0000256|RuleBase:RU361277}.
FT   DOMAIN       27    370       PKS_ER. {ECO:0000259|SMART:SM00829}.
SQ   SEQUENCE   376 AA;  40487 MW;  0B708F7758E9822A CRC64;
     MSYQKLQPGA SGAIGELAAM QAVVCHGPKD YRLETVAMPT IGRNELLISI AACGICASDC
     KCHSGAKMFW GGDGQPSWVK APVIPGHEFF GYVEALGEGA AEHFGVEKGD RVIAEQIVPC
     GKCRFCTSGK YWMCEVHNIF GFQRIVADGG MADYMRLPPT SRVHKIPDGI SLEDAAIIEP
     LSCAIHTVNR GDIQLDDVVV IAGAGPLGLM MVQAARLKTP KKLIVIDLVP ERLALAKEFG
     ADVTINPKTE NADAIVKGLT EGYGCDVYIE TTGAPIGVTQ GLEMIRKLGR FVEFSVFGSE
     TSADWSIIGD RKELDVRGAH LGPYCYPIAI DLLARGLVTS KGIVTHDFPL TEWERAFALA
     NSLDSIKVLL KPQPRS
//

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