(data stored in SCRATCH zone)

SWISSPROT: E6V3G1_VARPE

ID   E6V3G1_VARPE            Unreviewed;       705 AA.
AC   E6V3G1;
DT   08-MAR-2011, integrated into UniProtKB/TrEMBL.
DT   08-MAR-2011, sequence version 1.
DT   08-MAY-2019, entry version 49.
DE   RecName: Full=DNA helicase {ECO:0000256|SAAS:SAAS00413339};
DE            EC=3.6.4.12 {ECO:0000256|SAAS:SAAS00413339};
GN   OrderedLocusNames=Varpa_0429 {ECO:0000313|EMBL:ADU34651.1};
OS   Variovorax paradoxus (strain EPS).
OC   Bacteria; Proteobacteria; Betaproteobacteria; Burkholderiales;
OC   Comamonadaceae; Variovorax.
OX   NCBI_TaxID=595537 {ECO:0000313|EMBL:ADU34651.1, ECO:0000313|Proteomes:UP000008917};
RN   [1] {ECO:0000313|Proteomes:UP000008917}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=EPS {ECO:0000313|Proteomes:UP000008917};
RG   US DOE Joint Genome Institute;
RA   Lucas S., Copeland A., Lapidus A., Cheng J.-F., Goodwin L.,
RA   Pitluck S., Teshima H., Detter J.C., Han C., Tapia R., Land M.,
RA   Hauser L., Kyrpides N., Ivanova N., Ovchinnikova G., Orwin P.,
RA   Han J.-I.G., Woyke T.;
RT   "Complete sequence of Variovorax paradoxus EPS.";
RL   Submitted (DEC-2010) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EMBL:ADU34651.1, ECO:0000313|Proteomes:UP000008917}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=EPS {ECO:0000313|EMBL:ADU34651.1,
RC   ECO:0000313|Proteomes:UP000008917};
RX   PubMed=24158554;
RA   Han J.I., Spain J.C., Leadbetter J.R., Ovchinnikova G., Goodwin L.A.,
RA   Han C.S., Woyke T., Davenport K.W., Orwin P.M.;
RT   "Genome of the Root-Associated Plant Growth-Promoting Bacterium
RT   Variovorax paradoxus Strain EPS.";
RL   Genome Announc. 1:e00843-13(2013).
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC         ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC         ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=3.6.4.12;
CC         Evidence={ECO:0000256|SAAS:SAAS01129065};
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DR   EMBL; CP002417; ADU34651.1; -; Genomic_DNA.
DR   RefSeq; WP_013538897.1; NC_014931.1.
DR   STRING; 595537.Varpa_0429; -.
DR   EnsemblBacteria; ADU34651; ADU34651; Varpa_0429.
DR   GeneID; 29719820; -.
DR   KEGG; vpe:Varpa_0429; -.
DR   eggNOG; ENOG4105C4R; Bacteria.
DR   eggNOG; COG0210; LUCA.
DR   HOGENOM; HOG000033017; -.
DR   KO; K03657; -.
DR   OMA; LLLYWAQ; -.
DR   OrthoDB; 137860at2; -.
DR   BioCyc; VPAR595537:G1GQO-431-MONOMER; -.
DR   Proteomes; UP000008917; Chromosome.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004003; F:ATP-dependent DNA helicase activity; IEA:InterPro.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   Gene3D; 1.10.10.160; -; 1.
DR   InterPro; IPR013986; DExx_box_DNA_helicase_dom_sf.
DR   InterPro; IPR014017; DNA_helicase_UvrD-like_C.
DR   InterPro; IPR000212; DNA_helicase_UvrD/REP.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR014016; UvrD-like_ATP-bd.
DR   PANTHER; PTHR11070; PTHR11070; 1.
DR   Pfam; PF13361; UvrD_C; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   PROSITE; PS51198; UVRD_HELICASE_ATP_BIND; 1.
DR   PROSITE; PS51217; UVRD_HELICASE_CTER; 1.
PE   4: Predicted;
DR   PRODOM; E6V3G1.
DR   SWISS-2DPAGE; E6V3G1.
KW   ATP-binding {ECO:0000256|SAAS:SAAS00146071};
KW   Complete proteome {ECO:0000313|Proteomes:UP000008917};
KW   DNA-binding {ECO:0000256|SAAS:SAAS00745286};
KW   Helicase {ECO:0000256|SAAS:SAAS00553650, ECO:0000313|EMBL:ADU34651.1};
KW   Hydrolase {ECO:0000256|SAAS:SAAS00146062};
KW   Nucleotide-binding {ECO:0000256|SAAS:SAAS00145996};
KW   Reference proteome {ECO:0000313|Proteomes:UP000008917}.
FT   DOMAIN       33    325       UvrD-like helicase ATP-binding.
FT                                {ECO:0000259|PROSITE:PS51198}.
FT   DOMAIN      326    590       UvrD-like helicase C-terminal.
FT                                {ECO:0000259|PROSITE:PS51217}.
SQ   SEQUENCE   705 AA;  77734 MW;  667B350E32C71956 CRC64;
     MQTAAPPVIS AAPKTQAERL AAALATLNDD QRAAVEHGVG AAVADDHRPL LVIAGAGSGK
     TSTLAHRVAH LIADGVDPQR LLLLTFSRRA AQEMERRAGQ VLAKVLGLKS ERPPALPWAG
     TFHGIGARLL REYAQQIGLD ENFTIHDRGD AEDLMGLVRH ELGLSSTVNR FPRKGTCLSI
     YSRCVNTRAS VAEVLKEAFP WCGEWEAELK TLFGAYVEAK QQQNVLDYDD LLLYWAEMVA
     EPALAEAVGA RFDHVLVDEY QDTNLLQASI LLAMKPDGRG VTVVGDDAQS IYSFRGATVR
     NILDFPSQFS REARVVTLER NYRSTQPILD VSNRVIAQAA ERHAKTLWTD KPSAGKPQLV
     LVPDEAGQAR WVADKVLAHR EGGLALKSQA VLFRTSSHSA ALELELARRN IPFVKFGGLK
     FLEASHVKDL LAVLRFAENP RGRMAGFRVT QLIPGIGPVT GTRLLDAMDQ AADPAAAVRD
     FVPPSAAREQ WAGFAEAYAA LRAPSLAWPA DVELAMGWYL PHLERLYDDT SGVRRQDVEQ
     LVRLAAGYGS RERFLTELTL DPPEATSDRP GPPLLDEDYL ILSTIHSAKG QEWNSVHVLN
     VVDGCLPADV AQSAHELEEE RRLLYVAMTR ARDHLHLLVP QRFYITQQAV RGDRHLYANR
     TRFITESDLA GFEQQTWPPP PVQPPAVPPP AAVIDLRNRM RAAWR
//

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