(data stored in ACNUC7421 zone)

SWISSPROT: Q4WA25_ASPFU

ID   Q4WA25_ASPFU            Unreviewed;      1375 AA.
AC   Q4WA25;
DT   05-JUL-2005, integrated into UniProtKB/TrEMBL.
DT   05-JUL-2005, sequence version 1.
DT   11-DEC-2019, entry version 106.
DE   SubName: Full=Sensor histidine kinase/response regulator, putative {ECO:0000313|EMBL:EAL84438.1};
GN   ORFNames=AFUA_4G02900 {ECO:0000313|EMBL:EAL84438.1};
OS   Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC
OS   A1100) (Aspergillus fumigatus).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus.
OX   NCBI_TaxID=330879 {ECO:0000313|EMBL:EAL84438.1, ECO:0000313|Proteomes:UP000002530};
RN   [1] {ECO:0000313|EMBL:EAL84438.1, ECO:0000313|Proteomes:UP000002530}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100
RC   {ECO:0000313|Proteomes:UP000002530};
RX   PubMed=16372009; DOI=10.1038/nature04332;
RA   Nierman W.C., Pain A., Anderson M.J., Wortman J.R., Kim H.S., Arroyo J.,
RA   Berriman M., Abe K., Archer D.B., Bermejo C., Bennett J., Bowyer P.,
RA   Chen D., Collins M., Coulsen R., Davies R., Dyer P.S., Farman M.,
RA   Fedorova N., Fedorova N., Feldblyum T.V., Fischer R., Fosker N., Fraser A.,
RA   Garcia J.L., Garcia M.J., Goble A., Goldman G.H., Gomi K.,
RA   Griffith-Jones S., Gwilliam R., Haas B., Haas H., Harris D., Horiuchi H.,
RA   Huang J., Humphray S., Jimenez J., Keller N., Khouri H., Kitamoto K.,
RA   Kobayashi T., Konzack S., Kulkarni R., Kumagai T., Lafon A., Latge J.P.,
RA   Li W., Lord A., Lu C., Majoros W.H., May G.S., Miller B.L., Mohamoud Y.,
RA   Molina M., Monod M., Mouyna I., Mulligan S., Murphy L., O'Neil S.,
RA   Paulsen I., Penalva M.A., Pertea M., Price C., Pritchard B.L., Quail M.A.,
RA   Rabbinowitsch E., Rawlins N., Rajandream M.A., Reichard U., Renauld H.,
RA   Robson G.D., Rodriguez de Cordoba S., Rodriguez-Pena J.M., Ronning C.M.,
RA   Rutter S., Salzberg S.L., Sanchez M., Sanchez-Ferrero J.C., Saunders D.,
RA   Seeger K., Squares R., Squares S., Takeuchi M., Tekaia F., Turner G.,
RA   Vazquez de Aldana C.R., Weidman J., White O., Woodward J., Yu J.H.,
RA   Fraser C., Galagan J.E., Asai K., Machida M., Hall N., Barrell B.,
RA   Denning D.W.;
RT   "Genomic sequence of the pathogenic and allergenic filamentous fungus
RT   Aspergillus fumigatus.";
RL   Nature 438:1151-1156(2005).
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EAL84438.1}.
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DR   EMBL; AAHF01000016; EAL84438.1; -; Genomic_DNA.
DR   RefSeq; XP_746476.1; XM_741383.1.
DR   STRING; 746128.CADAFUBP00009741; -.
DR   EnsemblFungi; EAL84438; EAL84438; AFUA_4G02900.
DR   GeneID; 3503871; -.
DR   KEGG; afm:AFUA_4G02900; -.
DR   EuPathDB; FungiDB:Afu4g02900; -.
DR   HOGENOM; HOG000171704; -.
DR   InParanoid; Q4WA25; -.
DR   OMA; YDRDQET; -.
DR   OrthoDB; 27870at2759; -.
DR   Proteomes; UP000002530; Chromosome 4.
DR   GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR   GO; GO:0009584; P:detection of visible light; IEA:InterPro.
DR   GO; GO:0018298; P:protein-chromophore linkage; IEA:InterPro.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:InterPro.
DR   CDD; cd00082; HisKA; 1.
DR   CDD; cd00156; REC; 1.
DR   Gene3D; 3.30.450.40; -; 1.
DR   Gene3D; 3.30.565.10; -; 1.
DR   InterPro; IPR011006; CheY-like_superfamily.
DR   InterPro; IPR003018; GAF.
DR   InterPro; IPR029016; GAF-like_dom_sf.
DR   InterPro; IPR003594; HATPase_C.
DR   InterPro; IPR036890; HATPase_C_sf.
DR   InterPro; IPR005467; His_kinase_dom.
DR   InterPro; IPR003661; HisK_dim/P.
DR   InterPro; IPR036097; HisK_dim/P_sf.
DR   InterPro; IPR035965; PAS-like_dom_sf.
DR   InterPro; IPR013654; PAS_2.
DR   InterPro; IPR016132; Phyto_chromo_attachment.
DR   InterPro; IPR001294; Phytochrome.
DR   InterPro; IPR013515; Phytochrome_cen-reg.
DR   InterPro; IPR001789; Sig_transdc_resp-reg_receiver.
DR   Pfam; PF01590; GAF; 1.
DR   Pfam; PF02518; HATPase_c; 1.
DR   Pfam; PF00512; HisKA; 1.
DR   Pfam; PF08446; PAS_2; 1.
DR   Pfam; PF00360; PHY; 1.
DR   Pfam; PF00072; Response_reg; 1.
DR   PRINTS; PR01033; PHYTOCHROME.
DR   SMART; SM00387; HATPase_c; 1.
DR   SMART; SM00388; HisKA; 1.
DR   SMART; SM00448; REC; 1.
DR   SUPFAM; SSF47384; SSF47384; 1.
DR   SUPFAM; SSF52172; SSF52172; 1.
DR   SUPFAM; SSF55785; SSF55785; 1.
DR   SUPFAM; SSF55874; SSF55874; 1.
DR   PROSITE; PS50109; HIS_KIN; 1.
DR   PROSITE; PS50046; PHYTOCHROME_2; 1.
DR   PROSITE; PS50110; RESPONSE_REGULATORY; 1.
PE   4: Predicted;
DR   PRODOM; Q4WA25.
DR   SWISS-2DPAGE; Q4WA25.
KW   Kinase {ECO:0000313|EMBL:EAL84438.1};
KW   Phosphoprotein {ECO:0000256|PROSITE-ProRule:PRU00169};
KW   Reference proteome {ECO:0000313|Proteomes:UP000002530};
KW   Transferase {ECO:0000313|EMBL:EAL84438.1}.
FT   DOMAIN          389..551
FT                   /note="PHYTOCHROME_2"
FT                   /evidence="ECO:0000259|PROSITE:PS50046"
FT   DOMAIN          762..1002
FT                   /note="Histidine kinase"
FT                   /evidence="ECO:0000259|PROSITE:PS50109"
FT   DOMAIN          1218..1348
FT                   /note="Response regulatory"
FT                   /evidence="ECO:0000259|PROSITE:PS50110"
FT   REGION          1..89
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          106..162
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1005..1024
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1034..1122
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1135..1163
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1176..1212
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        61..86
FT                   /note="Polar"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        125..151
FT                   /note="Polar"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1054..1089
FT                   /note="Polar"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1090..1106
FT                   /note="Polyampholyte"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1108..1122
FT                   /note="Polar"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   MOD_RES         1269
FT                   /note="4-aspartylphosphate"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00169"
SQ   SEQUENCE   1375 AA;  152103 MW;  BCB18FAE241F54B0 CRC64;
     MASRANASSP TRQKNDEDLS ETTSGAVGEE GAVTRAPKSG MESSTGFESE DRVYPIRSVI
     SVDPSTVSQS QQQAESNLSS PATGAREWSI INAETWDKMR AQTKTSAGNF SATEPPPPAP
     DTAGSSSEPP DQGRSHSASP TPTPDSALTK TQDPEVDSEH GLVTARFRHV VTDGGHMVIT
     GRANDSYQAC EDEPIHIPGA VQSFGCLLVL REEIEGKLVV RVASENSEVI LGHSPKCLFA
     LPNFCDILDE EQKDNLLDHL DLIRDDGFDP SVDGPEVFLL SVKLPSGKPR RFWCATHLSP
     ADSNSIICEF ELEDDRINPL SVSGLTTPVT PTDTLGVEPT PEQLEHSTVN ISQPLRLLRN
     ARRRRGEAAA MEVFSILSQI QDQLGRTKSL DSLLNTTTGL VKELTGFHRV LIYQFDTEWN
     GTVVAELVDP KASVDLYKGL CFPASDIPKQ ARDLYRINKV RLLYDRDQVT SRLVCRTLED
     LQTPVDMTHS YLRAMSPIHL KYLANMGVRA SMSISISGFN ELWGLISCHT YGTHGMRVSF
     PVRKICRLIG DTVSRNIERL SYASRLQARK LINTVPTDQN PSGYIIATSD DLLKLFDADY
     GALSIRNETK LLGKMTHSQE ILALLEYLRM QRMNSVVASH HITKDFPDLF YAPGFKHISG
     MLYVPLSAGG TDFMVFFRRG HLTEIKWAGN PYDKKPQNGH LEPRKSFQTW RETVLDQSRE
     WTESDVETAA VLCLVYGKFI KVWRQKEAAM ENSQLTRLLL ANSAHEFRTP LNAVINYLEI
     ALEGSLDPET RDNLTKSYSA SKSLIYVIND LLDLTNAEKG QKLIKDEIFD LPATFREATD
     MFEGEAKRKS IHYKVVAHPG LPPAVIGDQR RVRQVFTNLI SNAVRHTTAG SVTTEIWRSL
     EQAQPGCVVV QMTVLDTGSG MSQSTLEALF QELEQVSTDD DNYWFDPEDQ THPLDSCSQD
     KRVLGLGLAL VARIVRNMHG QLSVRSEKGK GSYFEISLNF PVPDDVASGE SEEPSVPDIV
     EPAVPIQQEV EFMLVDSKST RGGEQRRRST GSDHSKGSYN SSRSGRSNRS EADRLISAMQ
     DSPLLQRTTS EGSEERDPRP VERTQGSAHN RHAMSTQSLP NLKDESIPEQ WPVTQAPAFP
     STSRTMMPPV SPPLPGHEPV TDSGVPMTAI RIPLEDVERP PSPPAKAFLS QPGTSAELPS
     AAEPSSAPAP NAEPTTLRVL VAEDDPVNSK IVEKRLSKLG HAVILTGNGE ECAAAFRRDS
     TKVDVVLMDI QMPIVDGTES TRMIRQFEQE FQPPLSEKAS RNGHVPVFAV SASLLEKDAQ
     LYIEAGFDGW IMKPINFNRL GVLLDSLENH DIRNATIYRP GYWELGGWFK HHGEL
//

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