(data stored in ACNUC7421 zone)

SWISSPROT: Q4WD75_ASPFU

ID   Q4WD75_ASPFU            Unreviewed;       470 AA.
AC   Q4WD75;
DT   05-JUL-2005, integrated into UniProtKB/TrEMBL.
DT   05-JUL-2005, sequence version 1.
DT   11-DEC-2019, entry version 78.
DE   SubName: Full=HhH-GPD family base excision DNA repair protein {ECO:0000313|EMBL:EAL85663.1};
DE            EC=4.2.99.18 {ECO:0000313|EMBL:EAL85663.1};
GN   ORFNames=AFUA_6G03760 {ECO:0000313|EMBL:EAL85663.1};
OS   Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC
OS   A1100) (Aspergillus fumigatus).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus.
OX   NCBI_TaxID=330879 {ECO:0000313|EMBL:EAL85663.1, ECO:0000313|Proteomes:UP000002530};
RN   [1] {ECO:0000313|EMBL:EAL85663.1, ECO:0000313|Proteomes:UP000002530}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100
RC   {ECO:0000313|Proteomes:UP000002530};
RX   PubMed=16372009; DOI=10.1038/nature04332;
RA   Nierman W.C., Pain A., Anderson M.J., Wortman J.R., Kim H.S., Arroyo J.,
RA   Berriman M., Abe K., Archer D.B., Bermejo C., Bennett J., Bowyer P.,
RA   Chen D., Collins M., Coulsen R., Davies R., Dyer P.S., Farman M.,
RA   Fedorova N., Fedorova N., Feldblyum T.V., Fischer R., Fosker N., Fraser A.,
RA   Garcia J.L., Garcia M.J., Goble A., Goldman G.H., Gomi K.,
RA   Griffith-Jones S., Gwilliam R., Haas B., Haas H., Harris D., Horiuchi H.,
RA   Huang J., Humphray S., Jimenez J., Keller N., Khouri H., Kitamoto K.,
RA   Kobayashi T., Konzack S., Kulkarni R., Kumagai T., Lafon A., Latge J.P.,
RA   Li W., Lord A., Lu C., Majoros W.H., May G.S., Miller B.L., Mohamoud Y.,
RA   Molina M., Monod M., Mouyna I., Mulligan S., Murphy L., O'Neil S.,
RA   Paulsen I., Penalva M.A., Pertea M., Price C., Pritchard B.L., Quail M.A.,
RA   Rabbinowitsch E., Rawlins N., Rajandream M.A., Reichard U., Renauld H.,
RA   Robson G.D., Rodriguez de Cordoba S., Rodriguez-Pena J.M., Ronning C.M.,
RA   Rutter S., Salzberg S.L., Sanchez M., Sanchez-Ferrero J.C., Saunders D.,
RA   Seeger K., Squares R., Squares S., Takeuchi M., Tekaia F., Turner G.,
RA   Vazquez de Aldana C.R., Weidman J., White O., Woodward J., Yu J.H.,
RA   Fraser C., Galagan J.E., Asai K., Machida M., Hall N., Barrell B.,
RA   Denning D.W.;
RT   "Genomic sequence of the pathogenic and allergenic filamentous fungus
RT   Aspergillus fumigatus.";
RL   Nature 438:1151-1156(2005).
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EAL85663.1}.
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DR   EMBL; AAHF01000012; EAL85663.1; -; Genomic_DNA.
DR   RefSeq; XP_747701.1; XM_742608.1.
DR   STRING; 746128.CADAFUBP00009189; -.
DR   EnsemblFungi; EAL85663; EAL85663; AFUA_6G03760.
DR   GeneID; 3505067; -.
DR   KEGG; afm:AFUA_6G03760; -.
DR   EuPathDB; FungiDB:Afu6g03760; -.
DR   HOGENOM; HOG000201727; -.
DR   InParanoid; Q4WD75; -.
DR   KO; K01741; -.
DR   OMA; RHGKTCP; -.
DR   OrthoDB; 1280721at2759; -.
DR   Proteomes; UP000002530; Chromosome 6.
DR   GO; GO:0140078; F:class I DNA-(apurinic or apyrimidinic site) endonuclease activity; IEA:UniProtKB-EC.
DR   GO; GO:0006284; P:base-excision repair; IEA:InterPro.
DR   CDD; cd00056; ENDO3c; 1.
DR   Gene3D; 1.10.1670.10; -; 1.
DR   InterPro; IPR011257; DNA_glycosylase.
DR   InterPro; IPR003265; HhH-GPD_domain.
DR   InterPro; IPR023170; HTH_base_excis_C.
DR   SMART; SM00478; ENDO3c; 1.
DR   SUPFAM; SSF48150; SSF48150; 1.
PE   4: Predicted;
DR   PRODOM; Q4WD75.
DR   SWISS-2DPAGE; Q4WD75.
KW   Lyase {ECO:0000313|EMBL:EAL85663.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000002530}.
FT   DOMAIN          210..411
FT                   /note="ENDO3c"
FT                   /evidence="ECO:0000259|SMART:SM00478"
FT   REGION          18..114
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          442..470
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        25..39
FT                   /note="Polar"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        47..64
FT                   /note="Polyampholyte"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        65..97
FT                   /note="Polar"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   470 AA;  51355 MW;  3AD60FCC094EAB33 CRC64;
     MTRRVTRSAA AREAALFAAK AQDVKPQLTD SNGPDVSPKT GKSTPGRKRK LPIEHPEKLS
     KSSKTSKPKG SLPSLNVNDD LPHNLGSVSQ PHESINVEPK LNKQDPGIEE EEDLDNLASD
     LQKTVDKATE GLPQQIKISK KKNPYGLTPG ATPFPEWARP TPEECEEVNR LLSSAHGEVI
     PPSKIPEPSL TVTGCGEVPS VLDALIRTLL SGATTGRNSA LAFGGLVQRF GILEEGIGKG
     SVNWDAVRQA PLKDVFEAIK RGGLAEIKSR KIKAILDMVY QENQERKEFL VKGESDGSSD
     LMPGEKEYEI ACADQNFLSL NHLHTLSTED AMTELVKYPG IGPKTAACVI LFCLQRPCFA
     VDTHIFRICK WLGWVPPGKA TEVTAFSHLE VRIPDYLKYS LHQLLIRHGK TCPRCRAITG
     QSSAGWEDGC VIDHLVTRTG KKKEGNTNVP VASKRRTGRK IRAETDGSDE
//

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