(data stored in ACNUC7421 zone)

SWISSPROT: Q4WD66_ASPFU

ID   Q4WD66_ASPFU            Unreviewed;       415 AA.
AC   Q4WD66;
DT   05-JUL-2005, integrated into UniProtKB/TrEMBL.
DT   05-JUL-2005, sequence version 1.
DT   11-DEC-2019, entry version 94.
DE   SubName: Full=Biotin synthase, putative {ECO:0000313|EMBL:EAL85672.1};
DE            EC=2.8.1.6 {ECO:0000313|EMBL:EAL85672.1};
GN   ORFNames=AFUA_6G03670 {ECO:0000313|EMBL:EAL85672.1};
OS   Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC
OS   A1100) (Aspergillus fumigatus).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus.
OX   NCBI_TaxID=330879 {ECO:0000313|EMBL:EAL85672.1, ECO:0000313|Proteomes:UP000002530};
RN   [1] {ECO:0000313|EMBL:EAL85672.1, ECO:0000313|Proteomes:UP000002530}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100
RC   {ECO:0000313|Proteomes:UP000002530};
RX   PubMed=16372009; DOI=10.1038/nature04332;
RA   Nierman W.C., Pain A., Anderson M.J., Wortman J.R., Kim H.S., Arroyo J.,
RA   Berriman M., Abe K., Archer D.B., Bermejo C., Bennett J., Bowyer P.,
RA   Chen D., Collins M., Coulsen R., Davies R., Dyer P.S., Farman M.,
RA   Fedorova N., Fedorova N., Feldblyum T.V., Fischer R., Fosker N., Fraser A.,
RA   Garcia J.L., Garcia M.J., Goble A., Goldman G.H., Gomi K.,
RA   Griffith-Jones S., Gwilliam R., Haas B., Haas H., Harris D., Horiuchi H.,
RA   Huang J., Humphray S., Jimenez J., Keller N., Khouri H., Kitamoto K.,
RA   Kobayashi T., Konzack S., Kulkarni R., Kumagai T., Lafon A., Latge J.P.,
RA   Li W., Lord A., Lu C., Majoros W.H., May G.S., Miller B.L., Mohamoud Y.,
RA   Molina M., Monod M., Mouyna I., Mulligan S., Murphy L., O'Neil S.,
RA   Paulsen I., Penalva M.A., Pertea M., Price C., Pritchard B.L., Quail M.A.,
RA   Rabbinowitsch E., Rawlins N., Rajandream M.A., Reichard U., Renauld H.,
RA   Robson G.D., Rodriguez de Cordoba S., Rodriguez-Pena J.M., Ronning C.M.,
RA   Rutter S., Salzberg S.L., Sanchez M., Sanchez-Ferrero J.C., Saunders D.,
RA   Seeger K., Squares R., Squares S., Takeuchi M., Tekaia F., Turner G.,
RA   Vazquez de Aldana C.R., Weidman J., White O., Woodward J., Yu J.H.,
RA   Fraser C., Galagan J.E., Asai K., Machida M., Hall N., Barrell B.,
RA   Denning D.W.;
RT   "Genomic sequence of the pathogenic and allergenic filamentous fungus
RT   Aspergillus fumigatus.";
RL   Nature 438:1151-1156(2005).
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EAL85672.1}.
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DR   EMBL; AAHF01000012; EAL85672.1; -; Genomic_DNA.
DR   RefSeq; XP_747710.1; XM_742617.1.
DR   STRING; 746128.CADAFUBP00009198; -.
DR   PRIDE; Q4WD66; -.
DR   EnsemblFungi; EAL85672; EAL85672; AFUA_6G03670.
DR   GeneID; 3505064; -.
DR   KEGG; afm:AFUA_6G03670; -.
DR   EuPathDB; FungiDB:Afu6g03670; -.
DR   HOGENOM; HOG000239957; -.
DR   InParanoid; Q4WD66; -.
DR   KO; K01012; -.
DR   OMA; AMGVHRY; -.
DR   OrthoDB; 847045at2759; -.
DR   Proteomes; UP000002530; Chromosome 6.
DR   GO; GO:0051537; F:2 iron, 2 sulfur cluster binding; IBA:GO_Central.
DR   GO; GO:0004076; F:biotin synthase activity; IBA:GO_Central.
DR   GO; GO:0009102; P:biotin biosynthetic process; IBA:GO_Central.
DR   Gene3D; 3.20.20.70; -; 1.
DR   HAMAP; MF_01694; BioB; 1.
DR   InterPro; IPR013785; Aldolase_TIM.
DR   InterPro; IPR010722; BATS_dom.
DR   InterPro; IPR002684; Biotin_synth/BioAB.
DR   InterPro; IPR024177; Biotin_synthase.
DR   InterPro; IPR006638; Elp3/MiaB/NifB.
DR   InterPro; IPR007197; rSAM.
DR   PANTHER; PTHR22976; PTHR22976; 1.
DR   Pfam; PF06968; BATS; 1.
DR   Pfam; PF04055; Radical_SAM; 1.
DR   SFLD; SFLDF00272; biotin_synthase; 1.
DR   SMART; SM00876; BATS; 1.
DR   SMART; SM00729; Elp3; 1.
DR   TIGRFAMs; TIGR00433; bioB; 1.
PE   3: Inferred from homology;
DR   PRODOM; Q4WD66.
DR   SWISS-2DPAGE; Q4WD66.
KW   Reference proteome {ECO:0000313|Proteomes:UP000002530};
KW   Transferase {ECO:0000313|EMBL:EAL85672.1}.
FT   DOMAIN          105..313
FT                   /note="Elp3"
FT                   /evidence="ECO:0000259|SMART:SM00729"
FT   DOMAIN          284..376
FT                   /note="BATS"
FT                   /evidence="ECO:0000259|SMART:SM00876"
FT   REGION          383..415
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   415 AA;  45066 MW;  758FEA08CA14A1F7 CRC64;
     MSLSLSRSLH RALLRRSYGT VQAPPSAASL AANRIPPALQ EATAATAPRT NWSREEVQQI
     YETPLSQLTY AAVGRSLISY FSMDTDFCKA TVHRRFHDPA AIQMCTLMNI KTGGCSEDCS
     YCAQSSRYNT GLKATKMSPV DEVLKAARIA KDNGSTRFCM GAAWRDMRGR KTSLKNIKEM
     VSGVRAMGME VCVTLGMIDE NQAKELKDAG LTAYNHNLDT SREFYPSIIT TRSYDERLRT
     LSHVRDAGIN VCSGGILGLG EADSDRIGLI HTVANLPSHP ESFPVNALVP IKGTPLGDRK
     MIPFDKLLRT IATARIVLPA TIVRLAAGRI SLSEEQQVAC FMAGANAVFT GEKMLTTDCN
     GWDEDREMFE RWGFYPMRSF EKEGSTQPAV EAPSAAAPAP AAHDSVSAAP AAASS
//

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