(data stored in ACNUC7421 zone)

SWISSPROT: IPI1_ASPFU

ID   IPI1_ASPFU              Reviewed;         345 AA.
AC   Q4WCP8;
DT   23-OCT-2007, integrated into UniProtKB/Swiss-Prot.
DT   23-OCT-2007, sequence version 2.
DT   11-DEC-2019, entry version 77.
DE   RecName: Full=Pre-rRNA-processing protein ipi1;
GN   Name=ipi1; ORFNames=AFUA_6G01990;
OS   Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC
OS   A1100) (Aspergillus fumigatus).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus.
OX   NCBI_TaxID=330879;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100;
RX   PubMed=16372009; DOI=10.1038/nature04332;
RA   Nierman W.C., Pain A., Anderson M.J., Wortman J.R., Kim H.S., Arroyo J.,
RA   Berriman M., Abe K., Archer D.B., Bermejo C., Bennett J.W., Bowyer P.,
RA   Chen D., Collins M., Coulsen R., Davies R., Dyer P.S., Farman M.L.,
RA   Fedorova N., Fedorova N.D., Feldblyum T.V., Fischer R., Fosker N.,
RA   Fraser A., Garcia J.L., Garcia M.J., Goble A., Goldman G.H., Gomi K.,
RA   Griffith-Jones S., Gwilliam R., Haas B.J., Haas H., Harris D.E.,
RA   Horiuchi H., Huang J., Humphray S., Jimenez J., Keller N., Khouri H.,
RA   Kitamoto K., Kobayashi T., Konzack S., Kulkarni R., Kumagai T., Lafton A.,
RA   Latge J.-P., Li W., Lord A., Lu C., Majoros W.H., May G.S., Miller B.L.,
RA   Mohamoud Y., Molina M., Monod M., Mouyna I., Mulligan S., Murphy L.D.,
RA   O'Neil S., Paulsen I., Penalva M.A., Pertea M., Price C., Pritchard B.L.,
RA   Quail M.A., Rabbinowitsch E., Rawlins N., Rajandream M.A., Reichard U.,
RA   Renauld H., Robson G.D., Rodriguez de Cordoba S., Rodriguez-Pena J.M.,
RA   Ronning C.M., Rutter S., Salzberg S.L., Sanchez M., Sanchez-Ferrero J.C.,
RA   Saunders D., Seeger K., Squares R., Squares S., Takeuchi M., Tekaia F.,
RA   Turner G., Vazquez de Aldana C.R., Weidman J., White O., Woodward J.R.,
RA   Yu J.-H., Fraser C.M., Galagan J.E., Asai K., Machida M., Hall N.,
RA   Barrell B.G., Denning D.W.;
RT   "Genomic sequence of the pathogenic and allergenic filamentous fungus
RT   Aspergillus fumigatus.";
RL   Nature 438:1151-1156(2005).
CC   -!- FUNCTION: Component of the RIX1 complex required for processing of ITS2
CC       sequences from 35S pre-rRNA. {ECO:0000250|UniProtKB:P38803}.
CC   -!- SUBUNIT: Component of the RIX1 complex, composed of ipi1, rix1/ipi2 and
CC       ipi3 in a 1:2:2 stoichiometry. The complex interacts (via rix1) with
CC       mdn1 (via its hexameric AAA ATPase ring) and the pre-60S ribosome
CC       particles. {ECO:0000250|UniProtKB:P38803}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250|UniProtKB:P38803}.
CC   -!- SIMILARITY: Belongs to the IPI1/TEX10 family. {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=EAL85840.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
DR   EMBL; AAHF01000012; EAL85840.1; ALT_SEQ; Genomic_DNA.
DR   RefSeq; XP_747878.1; XM_742785.1.
DR   STRING; 746128.CADAFUBP00009364; -.
DR   GeneID; 3505330; -.
DR   KEGG; afm:AFUA_6G01990; -.
DR   EuPathDB; FungiDB:Afu6g01990; -.
DR   HOGENOM; HOG000048652; -.
DR   InParanoid; Q4WCP8; -.
DR   KO; K14827; -.
DR   OrthoDB; 1145058at2759; -.
DR   Proteomes; UP000002530; Chromosome 6.
DR   Proteomes; UP000002530; Unassembled WGS sequence.
DR   GO; GO:0071339; C:MLL1 complex; IBA:GO_Central.
DR   GO; GO:0097344; C:Rix1 complex; IBA:GO_Central.
DR   GO; GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.
DR   InterPro; IPR016024; ARM-type_fold.
DR   InterPro; IPR024679; Ipi1_N.
DR   InterPro; IPR037947; TEX10/Ipi1.
DR   PANTHER; PTHR16056:SF2; PTHR16056:SF2; 1.
DR   Pfam; PF12333; Ipi1_N; 1.
DR   SUPFAM; SSF48371; SSF48371; 1.
PE   3: Inferred from homology;
DR   PRODOM; Q4WCP8.
DR   SWISS-2DPAGE; Q4WCP8.
KW   Nucleus; Reference proteome; Ribosome biogenesis; rRNA processing.
FT   CHAIN           1..345
FT                   /note="Pre-rRNA-processing protein ipi1"
FT                   /id="PRO_0000308714"
SQ   SEQUENCE   345 AA;  37419 MW;  1204AE531A55B9B8 CRC64;
     MGSSAKKKKE KKKDFQKTKL KVGKTKAKPD NFTDTSFRAK TITLNQQSLH ITAPSSDAQF
     THHVSLLSSK SDTQRRDSLA HLTTSLVSRP VDSPLPQPVS VLLPTLLPLI LDASSSVRTQ
     LLKLLRALPA NDIQDHVPQL LPYIRAGMTH LAADIRVSAV EVLSWLVDVA GAEVVSCAGG
     WIKTLNCFLS VLGWHTEESS KWSGNRASFG KSGAKGQPMV KVLAALAVFL QAGIGRPDER
     MDDSSDEDSA PGVSGWEFPL CHAAQHMVPQ ATAPFVHLNL FGQPRDEEGE MYETREDRYR
     VFENRFLGAV QRGLESARGE GGEVGRASAG VSKVLKEAIA YGPGV
//

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