(data stored in ACNUC7421 zone)

SWISSPROT: Q4WNP5_ASPFU

ID   Q4WNP5_ASPFU            Unreviewed;       916 AA.
AC   Q4WNP5;
DT   05-JUL-2005, integrated into UniProtKB/TrEMBL.
DT   05-JUL-2005, sequence version 1.
DT   11-DEC-2019, entry version 93.
DE   SubName: Full=DNA mismatch repair protein (Mlh3), putative {ECO:0000313|EMBL:EAL90139.1};
GN   ORFNames=AFUA_4G06490 {ECO:0000313|EMBL:EAL90139.1};
OS   Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC
OS   A1100) (Aspergillus fumigatus).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus.
OX   NCBI_TaxID=330879 {ECO:0000313|EMBL:EAL90139.1, ECO:0000313|Proteomes:UP000002530};
RN   [1] {ECO:0000313|EMBL:EAL90139.1, ECO:0000313|Proteomes:UP000002530}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100
RC   {ECO:0000313|Proteomes:UP000002530};
RX   PubMed=16372009; DOI=10.1038/nature04332;
RA   Nierman W.C., Pain A., Anderson M.J., Wortman J.R., Kim H.S., Arroyo J.,
RA   Berriman M., Abe K., Archer D.B., Bermejo C., Bennett J., Bowyer P.,
RA   Chen D., Collins M., Coulsen R., Davies R., Dyer P.S., Farman M.,
RA   Fedorova N., Fedorova N., Feldblyum T.V., Fischer R., Fosker N., Fraser A.,
RA   Garcia J.L., Garcia M.J., Goble A., Goldman G.H., Gomi K.,
RA   Griffith-Jones S., Gwilliam R., Haas B., Haas H., Harris D., Horiuchi H.,
RA   Huang J., Humphray S., Jimenez J., Keller N., Khouri H., Kitamoto K.,
RA   Kobayashi T., Konzack S., Kulkarni R., Kumagai T., Lafon A., Latge J.P.,
RA   Li W., Lord A., Lu C., Majoros W.H., May G.S., Miller B.L., Mohamoud Y.,
RA   Molina M., Monod M., Mouyna I., Mulligan S., Murphy L., O'Neil S.,
RA   Paulsen I., Penalva M.A., Pertea M., Price C., Pritchard B.L., Quail M.A.,
RA   Rabbinowitsch E., Rawlins N., Rajandream M.A., Reichard U., Renauld H.,
RA   Robson G.D., Rodriguez de Cordoba S., Rodriguez-Pena J.M., Ronning C.M.,
RA   Rutter S., Salzberg S.L., Sanchez M., Sanchez-Ferrero J.C., Saunders D.,
RA   Seeger K., Squares R., Squares S., Takeuchi M., Tekaia F., Turner G.,
RA   Vazquez de Aldana C.R., Weidman J., White O., Woodward J., Yu J.H.,
RA   Fraser C., Galagan J.E., Asai K., Machida M., Hall N., Barrell B.,
RA   Denning D.W.;
RT   "Genomic sequence of the pathogenic and allergenic filamentous fungus
RT   Aspergillus fumigatus.";
RL   Nature 438:1151-1156(2005).
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EAL90139.1}.
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DR   EMBL; AAHF01000005; EAL90139.1; -; Genomic_DNA.
DR   RefSeq; XP_752177.1; XM_747084.1.
DR   STRING; 746128.CADAFUBP00006183; -.
DR   EnsemblFungi; EAL90139; EAL90139; AFUA_4G06490.
DR   GeneID; 3509097; -.
DR   KEGG; afm:AFUA_4G06490; -.
DR   EuPathDB; FungiDB:Afu4g06490; -.
DR   HOGENOM; HOG000188023; -.
DR   InParanoid; Q4WNP5; -.
DR   KO; K08739; -.
DR   OMA; MPVRVKS; -.
DR   OrthoDB; 735423at2759; -.
DR   Proteomes; UP000002530; Chromosome 4.
DR   GO; GO:0032300; C:mismatch repair complex; IBA:GO_Central.
DR   GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR   GO; GO:0016887; F:ATPase activity; IBA:GO_Central.
DR   GO; GO:0006298; P:mismatch repair; IBA:GO_Central.
DR   Gene3D; 3.30.565.10; -; 1.
DR   InterPro; IPR036890; HATPase_C_sf.
DR   InterPro; IPR028830; Mlh3.
DR   InterPro; IPR038973; MutL/Mlh/Pms.
DR   InterPro; IPR014790; MutL_C.
DR   InterPro; IPR037198; MutL_C_sf.
DR   PANTHER; PTHR10073; PTHR10073; 1.
DR   PANTHER; PTHR10073:SF47; PTHR10073:SF47; 1.
DR   Pfam; PF08676; MutL_C; 1.
DR   SMART; SM00853; MutL_C; 1.
DR   SUPFAM; SSF118116; SSF118116; 1.
DR   SUPFAM; SSF55874; SSF55874; 1.
PE   4: Predicted;
DR   PRODOM; Q4WNP5.
DR   SWISS-2DPAGE; Q4WNP5.
KW   Reference proteome {ECO:0000313|Proteomes:UP000002530}.
FT   DOMAIN          660..853
FT                   /note="MutL_C"
FT                   /evidence="ECO:0000259|SMART:SM00853"
FT   REGION          386..420
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          463..489
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        396..420
FT                   /note="Polar"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   916 AA;  101119 MW;  37BCFAC3A9B7A363 CRC64;
     MPSEDSRIEP LPPEVVAKIK SSTSIINLNR VVVELVKNAL DANARTVSVT VDFHRGGCVV
     EDDGDGIPPA EFESDGGLGK AHHTSKLYSA RAVYGRRGLF LASLASLSLL TVISHHVRYN
     STNSVIFHHS TPIARFIPAP SSHQLSCSSH GTRVIVNDLF GNMPVRVKSR ALALQKPDEF
     ERQWDDLRRL LVSLILANDH LTKLVVSTAG KERKLMIRPH VGRPGIRGDL DLKRIASILM
     QAGLIESQNS DSWNYVSASV PGISLRAAVS LVPSPTRKVQ FISIGIDPVY PRNSTDLLYS
     EINRLFALSD FGAVEAAPVS SDGHPGPRFT SKAVNKWPMF YIRIDVDDPR ELFEEGHEVV
     PESNQSVQRL IDVLVAMMSE FLKQHGLRPR AGRQTKDVSR SASVESPGAG RSNFAKSVSS
     RDRSSIAEEA LAGQLKLPTF RRLTSTNTTS DFATWSRVKC AREPPASKHE LAGGLKKAHS
     GPAWESGDRE SLSLCLETDD SSVGNNLDLE VTENDGSDAD ASIPWTDPHT GYSHLINART
     GQAINVRSPS TEITVDERPR SAGTIQTLRA LDRSRPRSAI SSTSHNIWVE SLLRRWENPA
     FRRPERPITA ISDGESHRNM SDNGLIRPFD CSRGSYGLDD FGLAKFRGRL SKSHLATANV
     IAQVDRKFIL VKLADGRSSR SALVLIDQHA ADERCRIESL FGAMFADGHR QVQSIRIDPI
     TFDIPLMEAA LFGKHADSFA SWGVGYTVER KSSARAALVV VTSLPTLIAE RCRLEPDLVS
     DMIRGEIWKH EENGQGALAL SDQRAQRSKV HRDELGVETE GNWVDRLTSC PQGIIDLLNS
     RACRTAIMFN DMLTAEECKS LCAHGRPSMV PILDVRESEE FLGKSIECEY EYEREDGRRQ
     LDFLEAFRSW QGLGGN
//

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