(data stored in ACNUC7421 zone)

SWISSPROT: Q4WNP3_ASPFU

ID   Q4WNP3_ASPFU            Unreviewed;       730 AA.
AC   Q4WNP3;
DT   05-JUL-2005, integrated into UniProtKB/TrEMBL.
DT   05-JUL-2005, sequence version 1.
DT   11-DEC-2019, entry version 70.
DE   SubName: Full=Pentafunctional AROM polypeptide, putative {ECO:0000313|EMBL:EAL90141.1};
DE            EC=4.2.1.10 {ECO:0000313|EMBL:EAL90141.1};
GN   ORFNames=AFUA_4G06460 {ECO:0000313|EMBL:EAL90141.1};
OS   Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC
OS   A1100) (Aspergillus fumigatus).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus.
OX   NCBI_TaxID=330879 {ECO:0000313|EMBL:EAL90141.1, ECO:0000313|Proteomes:UP000002530};
RN   [1] {ECO:0000313|EMBL:EAL90141.1, ECO:0000313|Proteomes:UP000002530}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100
RC   {ECO:0000313|Proteomes:UP000002530};
RX   PubMed=16372009; DOI=10.1038/nature04332;
RA   Nierman W.C., Pain A., Anderson M.J., Wortman J.R., Kim H.S., Arroyo J.,
RA   Berriman M., Abe K., Archer D.B., Bermejo C., Bennett J., Bowyer P.,
RA   Chen D., Collins M., Coulsen R., Davies R., Dyer P.S., Farman M.,
RA   Fedorova N., Fedorova N., Feldblyum T.V., Fischer R., Fosker N., Fraser A.,
RA   Garcia J.L., Garcia M.J., Goble A., Goldman G.H., Gomi K.,
RA   Griffith-Jones S., Gwilliam R., Haas B., Haas H., Harris D., Horiuchi H.,
RA   Huang J., Humphray S., Jimenez J., Keller N., Khouri H., Kitamoto K.,
RA   Kobayashi T., Konzack S., Kulkarni R., Kumagai T., Lafon A., Latge J.P.,
RA   Li W., Lord A., Lu C., Majoros W.H., May G.S., Miller B.L., Mohamoud Y.,
RA   Molina M., Monod M., Mouyna I., Mulligan S., Murphy L., O'Neil S.,
RA   Paulsen I., Penalva M.A., Pertea M., Price C., Pritchard B.L., Quail M.A.,
RA   Rabbinowitsch E., Rawlins N., Rajandream M.A., Reichard U., Renauld H.,
RA   Robson G.D., Rodriguez de Cordoba S., Rodriguez-Pena J.M., Ronning C.M.,
RA   Rutter S., Salzberg S.L., Sanchez M., Sanchez-Ferrero J.C., Saunders D.,
RA   Seeger K., Squares R., Squares S., Takeuchi M., Tekaia F., Turner G.,
RA   Vazquez de Aldana C.R., Weidman J., White O., Woodward J., Yu J.H.,
RA   Fraser C., Galagan J.E., Asai K., Machida M., Hall N., Barrell B.,
RA   Denning D.W.;
RT   "Genomic sequence of the pathogenic and allergenic filamentous fungus
RT   Aspergillus fumigatus.";
RL   Nature 438:1151-1156(2005).
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EAL90141.1}.
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DR   EMBL; AAHF01000005; EAL90141.1; -; Genomic_DNA.
DR   RefSeq; XP_752179.1; XM_747086.1.
DR   STRING; 746128.CADAFUBP00006181; -.
DR   EnsemblFungi; EAL90141; EAL90141; AFUA_4G06460.
DR   GeneID; 3509111; -.
DR   KEGG; afm:AFUA_4G06460; -.
DR   EuPathDB; FungiDB:Afu4g06460; -.
DR   HOGENOM; HOG000188000; -.
DR   InParanoid; Q4WNP3; -.
DR   KO; K03785; -.
DR   OMA; NGRFPMD; -.
DR   OrthoDB; 39786at2759; -.
DR   Proteomes; UP000002530; Chromosome 4.
DR   GO; GO:0003855; F:3-dehydroquinate dehydratase activity; IEA:UniProtKB-EC.
DR   CDD; cd00502; DHQase_I; 1.
DR   Gene3D; 3.20.20.70; -; 1.
DR   InterPro; IPR013785; Aldolase_TIM.
DR   InterPro; IPR001381; DHquinase_I.
DR   Pfam; PF01487; DHquinase_I; 1.
DR   TIGRFAMs; TIGR01093; aroD; 1.
PE   4: Predicted;
DR   PRODOM; Q4WNP3.
DR   SWISS-2DPAGE; Q4WNP3.
KW   Lyase {ECO:0000313|EMBL:EAL90141.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000002530}.
FT   REGION          519..548
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        519..543
FT                   /note="Polar"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   730 AA;  78987 MW;  351BD67868AFAED5 CRC64;
     MMQTAIHQPM AMTILADTAP SVTNNSASAP SPANGAHPPL ATAVSANSAV AAAPPSVPAD
     PPRTVVVVYR SGQDSIVHLV AEVLGKPWTT ETSLSTLVTG SNAVVVGILA AELARSLDEC
     DPSTLIVINT HCVDDGSSPD EALTDRCDYE FLYSHSPFLR RDLTRFLSLI LGQTRPHEDL
     KTKTRTNFIS TTFPDVHAAL PNLDILSVGS DAVEIRVDLL VEPSPQGVVS PVPSLRYVGQ
     QVMLLRQHTE LPIIFTTRCT KENGKFPMDD PMLFYRYLRR AIQWGCEYID VELWLPEEIR
     RRLAEQKGHS VIMSAFHDFS GTWKWTSPEA ARIFAESARY ADIVKMIAMV HTIEANYELE
     YFRSTVKARG AGDSSPLLSA VNMGQMGQLS RALNTVFSPI THPLLPMIAA PGQLTAAEIN
     EAMHIMGALP KRDLYVIGSF RATPQSMFME KCFNELSLPH TLTSIDRGPK GTIEGVIMQP
     SFGGASVNPP ISAATPYIPA VSEAARAIGL VDTIVVGESQ SQSQSQSQSQ SQSQSQSQPH
     GPPTARTLIG ENATWKGIRA TLTRDYVPSA YRGRAAIILA GSESDASAAI YALRSLGVGS
     IYTVGFRATG PLAAGLEPFT SIQSVKLVEQ PFVMVSALPP EKSLLVQPLL RHYRSNGRTS
     PRSTRGKVYL DLTASSGERK GDPVGVAVNA GWTAYGIDEV TAWTTVETMR LLVGQNVPFD
     FVRMASGRIY
//

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