(data stored in ACNUC7421 zone)

SWISSPROT: A4AVS8_MARSH

ID   A4AVS8_MARSH            Unreviewed;       154 AA.
AC   A4AVS8;
DT   03-APR-2007, integrated into UniProtKB/TrEMBL.
DT   03-APR-2007, sequence version 1.
DT   08-MAY-2019, entry version 56.
DE   RecName: Full=Alkyl hydroperoxide reductase AhpD {ECO:0000256|SAAS:SAAS00088523};
DE            EC=1.11.1.15 {ECO:0000256|SAAS:SAAS00088503};
GN   OrderedLocusNames=FB2170_01502 {ECO:0000313|EMBL:EAR00008.1};
OS   Maribacter sp. (strain HTCC2170 / KCCM 42371).
OC   Bacteria; Bacteroidetes; Flavobacteriia; Flavobacteriales;
OC   Flavobacteriaceae; Maribacter.
OX   NCBI_TaxID=313603 {ECO:0000313|EMBL:EAR00008.1, ECO:0000313|Proteomes:UP000001602};
RN   [1] {ECO:0000313|EMBL:EAR00008.1, ECO:0000313|Proteomes:UP000001602}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=HTCC2170 / KCCM 42371 {ECO:0000313|Proteomes:UP000001602};
RX   PubMed=21037013; DOI=10.1128/JB.01207-10;
RA   Oh H.M., Kang I., Yang S.J., Jang Y., Vergin K.L., Giovannoni S.J.,
RA   Cho J.C.;
RT   "Complete genome sequence of strain HTCC2170, a novel member of the
RT   genus Maribacter in the family Flavobacteriaceae.";
RL   J. Bacteriol. 193:303-304(2011).
CC   -!- FUNCTION: Antioxidant protein with alkyl hydroperoxidase activity.
CC       Required for the reduction of the AhpC active site cysteine
CC       residues and for the regeneration of the AhpC enzyme activity.
CC       {ECO:0000256|SAAS:SAAS00088543}.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=[protein]-dithiol + a hydroperoxide = [protein]-disulfide
CC         + an alcohol + H2O; Xref=Rhea:RHEA:10008, Rhea:RHEA-COMP:10593,
CC         Rhea:RHEA-COMP:10594, ChEBI:CHEBI:15377, ChEBI:CHEBI:29950,
CC         ChEBI:CHEBI:30879, ChEBI:CHEBI:35924, ChEBI:CHEBI:50058;
CC         EC=1.11.1.15; Evidence={ECO:0000256|SAAS:SAAS01124573};
CC   -!- SIMILARITY: Belongs to the AhpD family.
CC       {ECO:0000256|SAAS:SAAS00571262}.
CC   -----------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   -----------------------------------------------------------------------
DR   EMBL; CP002157; EAR00008.1; -; Genomic_DNA.
DR   RefSeq; WP_013304994.1; NC_014472.1.
DR   STRING; 313603.FB2170_01502; -.
DR   EnsemblBacteria; EAR00008; EAR00008; FB2170_01502.
DR   KEGG; fbc:FB2170_01502; -.
DR   eggNOG; ENOG4105MDH; Bacteria.
DR   eggNOG; COG2128; LUCA.
DR   HOGENOM; HOG000181201; -.
DR   OMA; AINLWNR; -.
DR   OrthoDB; 1893149at2; -.
DR   BioCyc; MSP313603:G1GNS-563-MONOMER; -.
DR   Proteomes; UP000001602; Chromosome.
DR   GO; GO:0004601; F:peroxidase activity; IEA:UniProtKB-KW.
DR   GO; GO:0051920; F:peroxiredoxin activity; IEA:UniProtKB-EC.
DR   Gene3D; 1.20.1290.10; -; 1.
DR   InterPro; IPR029032; AhpD-like.
DR   InterPro; IPR004675; AhpD_core.
DR   InterPro; IPR003779; CMD-like.
DR   Pfam; PF02627; CMD; 1.
DR   SUPFAM; SSF69118; SSF69118; 1.
DR   TIGRFAMs; TIGR00778; ahpD_dom; 1.
PE   3: Inferred from homology;
DR   PRODOM; A4AVS8.
DR   SWISS-2DPAGE; A4AVS8.
KW   Antioxidant {ECO:0000256|SAAS:SAAS00461132};
KW   Complete proteome {ECO:0000313|Proteomes:UP000001602};
KW   Disulfide bond {ECO:0000256|SAAS:SAAS00461175};
KW   Oxidoreductase {ECO:0000256|SAAS:SAAS00461144};
KW   Peroxidase {ECO:0000256|SAAS:SAAS00461184,
KW   ECO:0000313|EMBL:EAR00008.1};
KW   Redox-active center {ECO:0000256|SAAS:SAAS00461089};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001602}.
FT   DOMAIN       24     77       CMD. {ECO:0000259|Pfam:PF02627}.
SQ   SEQUENCE   154 AA;  17479 MW;  DBD5EA1517B223C5 CRC64;
     MSEVKFKNIR FNPDITPFHD LAKNMAKAVG YTADLAIDKQ LAQLLRLRVA QKNDCAYCVI
     LHAKASRDAG ISEAKTDNIS SWYNSELFNE VEKVTLAYCD VLTDGKLKDF QKYHDALTDH
     FNEKEIAEIA AIIINMNLWT RLKLAQGAIP FIKE
//

If you have problems or comments...

PBIL Back to PBIL home page