(data stored in ACNUC7421 zone)

SWISSPROT: A4ATH7_MARSH

ID   A4ATH7_MARSH            Unreviewed;       449 AA.
AC   A4ATH7;
DT   03-APR-2007, integrated into UniProtKB/TrEMBL.
DT   03-APR-2007, sequence version 1.
DT   16-JAN-2019, entry version 59.
DE   RecName: Full=Na(+)-translocating NADH-quinone reductase subunit A {ECO:0000256|HAMAP-Rule:MF_00425, ECO:0000256|SAAS:SAAS00694314};
DE            Short=Na(+)-NQR subunit A {ECO:0000256|HAMAP-Rule:MF_00425};
DE            Short=Na(+)-translocating NQR subunit A {ECO:0000256|HAMAP-Rule:MF_00425};
DE            EC=7.2.1.1 {ECO:0000256|HAMAP-Rule:MF_00425, ECO:0000256|SAAS:SAAS01102985};
DE   AltName: Full=NQR complex subunit A {ECO:0000256|HAMAP-Rule:MF_00425};
DE   AltName: Full=NQR-1 subunit A {ECO:0000256|HAMAP-Rule:MF_00425};
GN   Name=nqrA {ECO:0000256|HAMAP-Rule:MF_00425};
GN   OrderedLocusNames=FB2170_16721 {ECO:0000313|EMBL:EAR00747.1};
OS   Maribacter sp. (strain HTCC2170 / KCCM 42371).
OC   Bacteria; Bacteroidetes; Flavobacteriia; Flavobacteriales;
OC   Flavobacteriaceae; Maribacter.
OX   NCBI_TaxID=313603 {ECO:0000313|EMBL:EAR00747.1, ECO:0000313|Proteomes:UP000001602};
RN   [1] {ECO:0000313|EMBL:EAR00747.1, ECO:0000313|Proteomes:UP000001602}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=HTCC2170 / KCCM 42371 {ECO:0000313|Proteomes:UP000001602};
RX   PubMed=21037013; DOI=10.1128/JB.01207-10;
RA   Oh H.M., Kang I., Yang S.J., Jang Y., Vergin K.L., Giovannoni S.J.,
RA   Cho J.C.;
RT   "Complete genome sequence of strain HTCC2170, a novel member of the
RT   genus Maribacter in the family Flavobacteriaceae.";
RL   J. Bacteriol. 193:303-304(2011).
CC   -!- FUNCTION: NQR complex catalyzes the reduction of ubiquinone-1 to
CC       ubiquinol by two successive reactions, coupled with the transport
CC       of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE
CC       are probably involved in the second step, the conversion of
CC       ubisemiquinone to ubiquinol. {ECO:0000256|HAMAP-Rule:MF_00425,
CC       ECO:0000256|SAAS:SAAS00694322}.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=a ubiquinone + H(+) + n Na(+)(in) + NADH = a ubiquinol +
CC         n Na(+)(out) + NAD(+); Xref=Rhea:RHEA:47748, Rhea:RHEA-
CC         COMP:9565, Rhea:RHEA-COMP:9566, ChEBI:CHEBI:15378,
CC         ChEBI:CHEBI:16389, ChEBI:CHEBI:17976, ChEBI:CHEBI:29101,
CC         ChEBI:CHEBI:57540, ChEBI:CHEBI:57945; EC=7.2.1.1;
CC         Evidence={ECO:0000256|HAMAP-Rule:MF_00425,
CC         ECO:0000256|SAAS:SAAS01118460};
CC   -!- SUBUNIT: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE
CC       and NqrF. {ECO:0000256|HAMAP-Rule:MF_00425,
CC       ECO:0000256|SAAS:SAAS00694327}.
CC   -!- SIMILARITY: Belongs to the NqrA family. {ECO:0000256|HAMAP-
CC       Rule:MF_00425, ECO:0000256|SAAS:SAAS00694311}.
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DR   EMBL; CP002157; EAR00747.1; -; Genomic_DNA.
DR   RefSeq; WP_013304550.1; NC_014472.1.
DR   STRING; 313603.FB2170_16721; -.
DR   EnsemblBacteria; EAR00747; EAR00747; FB2170_16721.
DR   KEGG; fbc:FB2170_16721; -.
DR   eggNOG; ENOG4105DWQ; Bacteria.
DR   eggNOG; COG1726; LUCA.
DR   HOGENOM; HOG000273652; -.
DR   KO; K00346; -.
DR   OMA; DYHGMKP; -.
DR   OrthoDB; 688908at2; -.
DR   BioCyc; MSP313603:G1GNS-121-MONOMER; -.
DR   Proteomes; UP000001602; Chromosome.
DR   GO; GO:0016655; F:oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor; IEA:UniProtKB-UniRule.
DR   GO; GO:0006814; P:sodium ion transport; IEA:UniProtKB-UniRule.
DR   HAMAP; MF_00425; NqrA; 1.
DR   InterPro; IPR008703; NqrA.
DR   InterPro; IPR022615; NqrA_C_domain.
DR   PANTHER; PTHR37839; PTHR37839; 1.
DR   Pfam; PF05896; NQRA; 1.
DR   Pfam; PF11973; NQRA_SLBB; 1.
DR   TIGRFAMs; TIGR01936; nqrA; 1.
PE   3: Inferred from homology;
DR   PRODOM; A4ATH7.
DR   SWISS-2DPAGE; A4ATH7.
KW   Complete proteome {ECO:0000313|Proteomes:UP000001602};
KW   Ion transport {ECO:0000256|HAMAP-Rule:MF_00425,
KW   ECO:0000256|SAAS:SAAS00694315};
KW   NAD {ECO:0000256|HAMAP-Rule:MF_00425, ECO:0000256|SAAS:SAAS00694318};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001602};
KW   Sodium {ECO:0000256|HAMAP-Rule:MF_00425,
KW   ECO:0000256|SAAS:SAAS00694316};
KW   Sodium transport {ECO:0000256|HAMAP-Rule:MF_00425,
KW   ECO:0000256|SAAS:SAAS00694312};
KW   Translocase {ECO:0000256|HAMAP-Rule:MF_00425,
KW   ECO:0000256|SAAS:SAAS01102990};
KW   Transport {ECO:0000256|HAMAP-Rule:MF_00425,
KW   ECO:0000256|SAAS:SAAS00694320};
KW   Ubiquinone {ECO:0000256|HAMAP-Rule:MF_00425,
KW   ECO:0000256|SAAS:SAAS00694317}.
FT   DOMAIN      262    311       NQRA_SLBB. {ECO:0000259|Pfam:PF11973}.
SQ   SEQUENCE   449 AA;  49503 MW;  2460BE8F82617D26 CRC64;
     MSKDIRIRKG LNINLVGAAE QTTSKAVLSN VYAINLEDFH GITPKMLVKQ GAEVKAGQPL
     FYNKNCEEMM FVSPVSGELV EIVRGARRRI ITLKILADKT QTDTDNGIFN IENASSKEVK
     AHLLKSGCWP FVKQRPYDII ANPDANPKAI FVSGYTTAPL AAYSDYVLQG KENELQAAIT
     ALGKMTPGKV HVSVANSNSP LAGLKGIELH KVSGPHPAGL VGTQINKIAP INKGEVVWTV
     SPQDLVIMGE LLLTGKFNSE RVVALVGSSV KDPKYFTTKI GTEISTFLYG SGVNGENFRV
     INGDVLTGSK TRPDGYLGYY NNTVTAIPEG DDYELFGWNK PIFNKISTTR AMTFSWLQPK
     KKYDLTTNTN GEHRAFVVTG QYEEVFPMDI FPMQLLKACM VKDLDEMEQL GLYEVAPEDF
     SLTEFICISK QPHQQIIREG LDLLQKEIG
//

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