(data stored in ACNUC1104 zone)

SWISSPROT: Y2459_MYCTO

ID   Y2459_MYCTO             Reviewed;         508 AA.
AC   P9WJW8; L0TCL0; O53186; Q7D739;
DT   16-APR-2014, integrated into UniProtKB/Swiss-Prot.
DT   16-APR-2014, sequence version 1.
DT   08-MAY-2019, entry version 27.
DE   RecName: Full=Uncharacterized MFS-type transporter MT2534;
GN   OrderedLocusNames=MT2534;
OS   Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh).
OC   Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC   Mycobacterium; Mycobacterium tuberculosis complex.
OX   NCBI_TaxID=83331;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CDC 1551 / Oshkosh;
RX   PubMed=12218036; DOI=10.1128/JB.184.19.5479-5490.2002;
RA   Fleischmann R.D., Alland D., Eisen J.A., Carpenter L., White O.,
RA   Peterson J.D., DeBoy R.T., Dodson R.J., Gwinn M.L., Haft D.H.,
RA   Hickey E.K., Kolonay J.F., Nelson W.C., Umayam L.A., Ermolaeva M.D.,
RA   Salzberg S.L., Delcher A., Utterback T.R., Weidman J.F., Khouri H.M.,
RA   Gill J., Mikula A., Bishai W., Jacobs W.R. Jr., Venter J.C.,
RA   Fraser C.M.;
RT   "Whole-genome comparison of Mycobacterium tuberculosis clinical and
RT   laboratory strains.";
RL   J. Bacteriol. 184:5479-5490(2002).
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass
CC       membrane protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the major facilitator superfamily.
CC       {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=AAK46834.1; Type=Erroneous initiation; Evidence={ECO:0000305};
DR   EMBL; AE000516; AAK46834.1; ALT_INIT; Genomic_DNA.
DR   PIR; B70865; B70865.
DR   RefSeq; WP_003412642.1; NZ_KK341227.1.
DR   EnsemblBacteria; AAK46834; AAK46834; MT2534.
DR   KEGG; mtc:MT2534; -.
DR   PATRIC; fig|83331.31.peg.2735; -.
DR   Proteomes; UP000001020; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0055085; P:transmembrane transport; IEA:InterPro.
DR   CDD; cd06174; MFS; 1.
DR   InterPro; IPR011701; MFS.
DR   InterPro; IPR020846; MFS_dom.
DR   InterPro; IPR036259; MFS_trans_sf.
DR   Pfam; PF07690; MFS_1; 1.
DR   SUPFAM; SSF103473; SSF103473; 1.
DR   PROSITE; PS50850; MFS; 1.
PE   3: Inferred from homology;
DR   PRODOM; P9WJW8.
DR   SWISS-2DPAGE; P9WJW8.
KW   Cell membrane; Complete proteome; Membrane; Transmembrane;
KW   Transmembrane helix; Transport.
FT   CHAIN         1    508       Uncharacterized MFS-type transporter
FT                                MT2534.
FT                                /FTId=PRO_0000427757.
FT   TRANSMEM      9     29       Helical. {ECO:0000255}.
FT   TRANSMEM     46     66       Helical. {ECO:0000255}.
FT   TRANSMEM     75     95       Helical. {ECO:0000255}.
FT   TRANSMEM    104    124       Helical. {ECO:0000255}.
FT   TRANSMEM    136    156       Helical. {ECO:0000255}.
FT   TRANSMEM    163    183       Helical. {ECO:0000255}.
FT   TRANSMEM    194    214       Helical. {ECO:0000255}.
FT   TRANSMEM    222    242       Helical. {ECO:0000255}.
FT   TRANSMEM    265    285       Helical. {ECO:0000255}.
FT   TRANSMEM    297    317       Helical. {ECO:0000255}.
FT   TRANSMEM    328    348       Helical. {ECO:0000255}.
FT   TRANSMEM    354    374       Helical. {ECO:0000255}.
FT   TRANSMEM    399    419       Helical. {ECO:0000255}.
FT   TRANSMEM    479    499       Helical. {ECO:0000255}.
SQ   SEQUENCE   508 AA;  53479 MW;  382D710B286F71C3 CRC64;
     MTPRQRLTVL ATGLGIFMVF VDVNIVNVAL PSIQKVFHTG EQGLQWAVAG YSLGMAAVLM
     SCALLGDRYG RRRSFVFGVT LFVVSSIVCV LPVSLAVFTV ARVIQGLGAA FISVLSLALL
     SHSFPNPRMK ARAISNWMAI GMVGAASAPA LGGLMVDGLG WRSVFLVNVP LGAIVWLLTL
     VGVDESQDPE PTQLDWVGQL TLIPAVALIA YTIIEAPRFD RQSAGFVAAL LLAAGVLLWL
     FVRHEHRAAF PLVDLKLFAE PLYRSVLIVY FVVMSCFFGT LMVITQHFQN VRDLSPLHAG
     LMMLPVPAGF GVASLLAGRA VNKWGPQLPV LTCLAAMFIG LAIFAISMDH AHPVALVGLT
     IFGAGAGGCA TPLLHLGMTK VDDGRAGMAA GMLNLQRSLG GIFGVAFLGT IVAAWLGAAL
     PNTMADEIPD PIARAIVVDV IVDSANPHAH AAFIGPGHRI TAAQEDEIVL AADAVFVSGI
     KLALGGAAVL LTGAFVLGWT RFPRTPAS
//

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