(data stored in SCRATCH zone)

SWISSPROT: Q13ED6_RHOPS

ID   Q13ED6_RHOPS            Unreviewed;       550 AA.
AC   Q13ED6;
DT   31-OCT-2006, integrated into UniProtKB/TrEMBL.
DT   31-OCT-2006, sequence version 1.
DT   08-MAY-2019, entry version 81.
DE   SubName: Full=Na+/H+ antiporter {ECO:0000313|EMBL:ABE37553.1};
GN   OrderedLocusNames=RPD_0315 {ECO:0000313|EMBL:ABE37553.1};
OS   Rhodopseudomonas palustris (strain BisB5).
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Rhizobiales;
OC   Bradyrhizobiaceae; Rhodopseudomonas.
OX   NCBI_TaxID=316057 {ECO:0000313|EMBL:ABE37553.1, ECO:0000313|Proteomes:UP000001818};
RN   [1] {ECO:0000313|EMBL:ABE37553.1, ECO:0000313|Proteomes:UP000001818}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=BisB5 {ECO:0000313|EMBL:ABE37553.1,
RC   ECO:0000313|Proteomes:UP000001818};
RG   US DOE Joint Genome Institute;
RA   Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C.,
RA   Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H.,
RA   Pitluck S., Chain P., Malfatti S., Shin M., Vergez L., Schmutz J.,
RA   Larimer F., Land M., Hauser L., Pelletier D.A., Kyrpides N.,
RA   Lykidis A., Oda Y., Harwood C.S., Richardson P.;
RT   "Complete sequence of Rhodopseudomonas palustris BisB5.";
RL   Submitted (MAR-2006) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Na(+)/H(+) antiporter that extrudes sodium in exchange
CC       for external protons. {ECO:0000256|RuleBase:RU366002}.
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane
CC       {ECO:0000256|RuleBase:RU366002}; Multi-pass membrane protein
CC       {ECO:0000256|RuleBase:RU366002}.
CC   -!- SIMILARITY: Belongs to the monovalent cation:proton antiporter 1
CC       (CPA1) transporter (TC 2.A.36) family.
CC       {ECO:0000256|RuleBase:RU366002}.
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DR   EMBL; CP000283; ABE37553.1; -; Genomic_DNA.
DR   RefSeq; WP_011500742.1; NC_007958.1.
DR   STRING; 316057.RPD_0315; -.
DR   EnsemblBacteria; ABE37553; ABE37553; RPD_0315.
DR   KEGG; rpd:RPD_0315; -.
DR   eggNOG; ENOG4105EEQ; Bacteria.
DR   eggNOG; COG0025; LUCA.
DR   HOGENOM; HOG000263348; -.
DR   KO; K03316; -.
DR   OMA; RFCLMFF; -.
DR   OrthoDB; 1194802at2; -.
DR   BioCyc; RPAL316057:RPD_RS01600-MONOMER; -.
DR   Proteomes; UP000001818; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-UniRule.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0015385; F:sodium:proton antiporter activity; IEA:UniProtKB-UniRule.
DR   InterPro; IPR006153; Cation/H_exchanger.
DR   InterPro; IPR018422; Cation/H_exchanger_CPA1.
DR   InterPro; IPR004705; Cation/H_exchanger_CPA1_bac.
DR   PANTHER; PTHR10110; PTHR10110; 1.
DR   Pfam; PF00999; Na_H_Exchanger; 1.
DR   TIGRFAMs; TIGR00831; a_cpa1; 1.
PE   3: Inferred from homology;
DR   PRODOM; Q13ED6.
DR   SWISS-2DPAGE; Q13ED6.
KW   Antiport {ECO:0000256|RuleBase:RU366002};
KW   Cell inner membrane {ECO:0000256|RuleBase:RU366002};
KW   Cell membrane {ECO:0000256|RuleBase:RU366002};
KW   Complete proteome {ECO:0000313|Proteomes:UP000001818};
KW   Ion transport {ECO:0000256|RuleBase:RU366002};
KW   Membrane {ECO:0000256|RuleBase:RU366002};
KW   Sodium {ECO:0000256|RuleBase:RU366002};
KW   Sodium transport {ECO:0000256|RuleBase:RU366002};
KW   Transmembrane {ECO:0000256|RuleBase:RU366002};
KW   Transmembrane helix {ECO:0000256|RuleBase:RU366002};
KW   Transport {ECO:0000256|RuleBase:RU366002}.
FT   TRANSMEM     20     37       Helical. {ECO:0000256|RuleBase:RU366002}.
FT   TRANSMEM     44     64       Helical. {ECO:0000256|RuleBase:RU366002}.
FT   TRANSMEM     70     89       Helical. {ECO:0000256|RuleBase:RU366002}.
FT   TRANSMEM    101    122       Helical. {ECO:0000256|RuleBase:RU366002}.
FT   TRANSMEM    128    149       Helical. {ECO:0000256|RuleBase:RU366002}.
FT   TRANSMEM    170    190       Helical. {ECO:0000256|RuleBase:RU366002}.
FT   TRANSMEM    196    216       Helical. {ECO:0000256|RuleBase:RU366002}.
FT   TRANSMEM    283    304       Helical. {ECO:0000256|RuleBase:RU366002}.
FT   TRANSMEM    316    339       Helical. {ECO:0000256|RuleBase:RU366002}.
FT   TRANSMEM    359    383       Helical. {ECO:0000256|RuleBase:RU366002}.
FT   TRANSMEM    395    422       Helical. {ECO:0000256|RuleBase:RU366002}.
FT   DOMAIN       22    420       Na_H_Exchanger. {ECO:0000259|Pfam:
FT                                PF00999}.
SQ   SEQUENCE   550 AA;  59577 MW;  BDF63D34DB498C11 CRC64;
     MQVVAGPFHQ RHCGFVEAKF LIFLILLAVL AGTALLARRF HVAPAILLLL AGIVLAFIPG
     MPAIQLPPDL ILLLVLPPLI YSASVAMSWR EFRSNLRPIG LLAIGCVIFT ACAVAVATHY
     LLGLSWSVGF LLGAIVAPPD VVAPLAIARK LGLPRRIIVV LEGEGLANDA TALILYRFAL
     AAIMTGVFSL PKASGTFAAI MVGELAFGVA VGWLSLRARH YARDPQIEIT LSLLTPYIAY
     WIPEHLGGSG VIATVACGLY ISWNGPLLIP AATRLQGIFF WDLVIYLIEG LLFLLTGFQM
     RAILERSKAF PLDDIVAATL LVAAIVIVAR FLWVFPASYL PRILSKRLRI SDPSPPWRAV
     FVVAFTGVRG AVSLATALAL PFTLPDGSGF PDRDLILFVA FGVILITVVG LGSTLPAVVM
     ALGVARDGQS EHIAEHENEI AARREALSAA LASLDAMTND RELSDEVVTL LRARHDIRAN
     QLPASLDDEA YAVTADERAL VRELIAAERR FIHAQLRDGK ITDEARRRIE RDLDLEEASL
     ANREFRKGAQ
//

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