(data stored in SCRATCH zone)

SWISSPROT: Q13H77_PARXL

ID   Q13H77_PARXL            Unreviewed;       561 AA.
AC   Q13H77;
DT   22-AUG-2006, integrated into UniProtKB/TrEMBL.
DT   22-AUG-2006, sequence version 1.
DT   08-MAY-2019, entry version 79.
DE   SubName: Full=Putative pyruvate decarboxylase {ECO:0000313|EMBL:ABE36562.1};
DE            EC=2.2.1.6 {ECO:0000313|EMBL:ABE36562.1};
GN   ORFNames=Bxe_C0664 {ECO:0000313|EMBL:ABE36562.1};
OS   Paraburkholderia xenovorans (strain LB400).
OC   Bacteria; Proteobacteria; Betaproteobacteria; Burkholderiales;
OC   Burkholderiaceae; Paraburkholderia.
OX   NCBI_TaxID=266265 {ECO:0000313|EMBL:ABE36562.1, ECO:0000313|Proteomes:UP000001817};
RN   [1] {ECO:0000313|EMBL:ABE36562.1, ECO:0000313|Proteomes:UP000001817}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=LB400 {ECO:0000313|EMBL:ABE36562.1,
RC   ECO:0000313|Proteomes:UP000001817};
RX   PubMed=17030797; DOI=10.1073/pnas.0606924103;
RA   Chain P.S., Denef V.J., Konstantinidis K.T., Vergez L.M., Agullo L.,
RA   Reyes V.L., Hauser L., Cordova M., Gomez L., Gonzalez M., Land M.,
RA   Lao V., Larimer F., LiPuma J.J., Mahenthiralingam E., Malfatti S.A.,
RA   Marx C.J., Parnell J.J., Ramette A., Richardson P., Seeger M.,
RA   Smith D., Spilker T., Sul W.J., Tsoi T.V., Ulrich L.E., Zhulin I.B.,
RA   Tiedje J.M.;
RT   "Burkholderia xenovorans LB400 harbors a multi-replicon, 9.73-Mbp
RT   genome shaped for versatility.";
RL   Proc. Natl. Acad. Sci. U.S.A. 103:15280-15287(2006).
CC   -!- SIMILARITY: Belongs to the TPP enzyme family.
CC       {ECO:0000256|RuleBase:RU362132}.
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DR   EMBL; CP000272; ABE36562.1; -; Genomic_DNA.
DR   RefSeq; WP_011493818.1; NZ_CP008761.1.
DR   STRING; 266265.Bxe_C0664; -.
DR   EnsemblBacteria; ABE36562; ABE36562; Bxe_C0664.
DR   GeneID; 4010178; -.
DR   KEGG; bxb:DR64_7781; -.
DR   KEGG; bxe:Bxe_C0664; -.
DR   PATRIC; fig|266265.5.peg.8427; -.
DR   eggNOG; ENOG4105C7K; Bacteria.
DR   eggNOG; COG0028; LUCA.
DR   HOGENOM; HOG000258445; -.
DR   KO; K01652; -.
DR   OMA; WAIQETS; -.
DR   OrthoDB; 391134at2; -.
DR   BioCyc; BXEN266265:BXE_RS39830-MONOMER; -.
DR   Proteomes; UP000001817; Chromosome 3.
DR   GO; GO:0003984; F:acetolactate synthase activity; IEA:UniProtKB-EC.
DR   GO; GO:0000287; F:magnesium ion binding; IEA:InterPro.
DR   GO; GO:0030976; F:thiamine pyrophosphate binding; IEA:InterPro.
DR   InterPro; IPR029035; DHS-like_NAD/FAD-binding_dom.
DR   InterPro; IPR029061; THDP-binding.
DR   InterPro; IPR012000; Thiamin_PyroP_enz_cen_dom.
DR   InterPro; IPR012001; Thiamin_PyroP_enz_TPP-bd_dom.
DR   InterPro; IPR000399; TPP-bd_CS.
DR   InterPro; IPR011766; TPP_enzyme-bd_C.
DR   Pfam; PF02775; TPP_enzyme_C; 1.
DR   Pfam; PF00205; TPP_enzyme_M; 1.
DR   Pfam; PF02776; TPP_enzyme_N; 1.
DR   SUPFAM; SSF52467; SSF52467; 1.
DR   SUPFAM; SSF52518; SSF52518; 2.
DR   PROSITE; PS00187; TPP_ENZYMES; 1.
PE   3: Inferred from homology;
DR   PRODOM; Q13H77.
DR   SWISS-2DPAGE; Q13H77.
KW   Complete proteome {ECO:0000313|Proteomes:UP000001817};
KW   Pyruvate {ECO:0000313|EMBL:ABE36562.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001817};
KW   Thiamine pyrophosphate {ECO:0000256|RuleBase:RU362132};
KW   Transferase {ECO:0000313|EMBL:ABE36562.1}.
FT   DOMAIN       21    187       TPP_enzyme_N. {ECO:0000259|Pfam:PF02776}.
FT   DOMAIN      207    343       TPP_enzyme_M. {ECO:0000259|Pfam:PF00205}.
FT   DOMAIN      404    550       TPP_enzyme_C. {ECO:0000259|Pfam:PF02775}.
SQ   SEQUENCE   561 AA;  59951 MW;  40202A2104B8E603 CRC64;
     MPLSSHLFIR NMNLPVPVSS ASHAMLSVFA ANGIDRVFLV PGESYLGILD ALGDFPSIDV
     VTCRHESGAG FMACADARLT RRPGVVMVSR GPGAANAAIA IHTAEQDAIP LILVVGQVPK
     QRLRKGAFQE IDYGRMYGSV AKHVIEVTEP EALAAAAFDA IRIAGAGTPG PVVLVVPEDI
     QQQAVEASAW RATPAVPTLP EPVRVLELAG RLERAQRPLV IAGGVLDVPG GREALRRLAE
     HFAVPVAVSF RRHDLFPNDH ALYAGDLGLA NPEEQMRLFE SSDLVIALGS RVGDITTQGY
     RFPSHPVPAQ SFVHCHPDSA VVNRHLAAEM GFVCDPASLA AALVASNPSP SVGGRRAQWC
     ERLRDFATGY ARWPEPAADG AARAVDVARI LAKQMPGDAA ICLDAGAFAA PVYRHFPFCF
     PRRLMAPLSG AMGYGVPSAI ATQLRYPGQK TVCLVGDGGF LMTGNEIIAA VERRLPILFI
     LVNNQCYGSI RIHQNRHYPG RHVGTSLSNP DFVRIAEAYG LQARRVTREC ELDEAIAQAF
     AADEPCLIEV VTEPPGGPLP S
//

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