(data stored in SCRATCH zone)

SWISSPROT: Q13HK0_PARXL

ID   Q13HK0_PARXL            Unreviewed;       234 AA.
AC   Q13HK0;
DT   22-AUG-2006, integrated into UniProtKB/TrEMBL.
DT   22-AUG-2006, sequence version 1.
DT   08-MAY-2019, entry version 76.
DE   RecName: Full=6-phosphogluconolactonase {ECO:0000256|RuleBase:RU365095};
DE            Short=6PGL {ECO:0000256|RuleBase:RU365095};
DE            EC=3.1.1.31 {ECO:0000256|RuleBase:RU365095};
GN   Name=pgl {ECO:0000256|RuleBase:RU365095};
GN   ORFNames=Bxe_C0539 {ECO:0000313|EMBL:ABE36439.1};
OS   Paraburkholderia xenovorans (strain LB400).
OC   Bacteria; Proteobacteria; Betaproteobacteria; Burkholderiales;
OC   Burkholderiaceae; Paraburkholderia.
OX   NCBI_TaxID=266265 {ECO:0000313|EMBL:ABE36439.1, ECO:0000313|Proteomes:UP000001817};
RN   [1] {ECO:0000313|EMBL:ABE36439.1, ECO:0000313|Proteomes:UP000001817}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=LB400 {ECO:0000313|EMBL:ABE36439.1,
RC   ECO:0000313|Proteomes:UP000001817};
RX   PubMed=17030797; DOI=10.1073/pnas.0606924103;
RA   Chain P.S., Denef V.J., Konstantinidis K.T., Vergez L.M., Agullo L.,
RA   Reyes V.L., Hauser L., Cordova M., Gomez L., Gonzalez M., Land M.,
RA   Lao V., Larimer F., LiPuma J.J., Mahenthiralingam E., Malfatti S.A.,
RA   Marx C.J., Parnell J.J., Ramette A., Richardson P., Seeger M.,
RA   Smith D., Spilker T., Sul W.J., Tsoi T.V., Ulrich L.E., Zhulin I.B.,
RA   Tiedje J.M.;
RT   "Burkholderia xenovorans LB400 harbors a multi-replicon, 9.73-Mbp
RT   genome shaped for versatility.";
RL   Proc. Natl. Acad. Sci. U.S.A. 103:15280-15287(2006).
CC   -!- FUNCTION: Hydrolysis of 6-phosphogluconolactone to 6-
CC       phosphogluconate. {ECO:0000256|RuleBase:RU365095}.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=6-phospho-D-glucono-1,5-lactone + H2O = 6-phospho-D-
CC         gluconate + H(+); Xref=Rhea:RHEA:12556, ChEBI:CHEBI:15377,
CC         ChEBI:CHEBI:15378, ChEBI:CHEBI:57955, ChEBI:CHEBI:58759;
CC         EC=3.1.1.31; Evidence={ECO:0000256|RuleBase:RU365095};
CC   -!- PATHWAY: Carbohydrate degradation; pentose phosphate pathway; D-
CC       ribulose 5-phosphate from D-glucose 6-phosphate (oxidative stage):
CC       step 2/3. {ECO:0000256|RuleBase:RU365095}.
CC   -!- SIMILARITY: Belongs to the glucosamine/galactosamine-6-phosphate
CC       isomerase family. 6-phosphogluconolactonase subfamily.
CC       {ECO:0000256|RuleBase:RU365095}.
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DR   EMBL; CP000272; ABE36439.1; -; Genomic_DNA.
DR   RefSeq; WP_011493695.1; NZ_CP008761.1.
DR   STRING; 266265.Bxe_C0539; -.
DR   EnsemblBacteria; ABE36439; ABE36439; Bxe_C0539.
DR   GeneID; 4010053; -.
DR   KEGG; bxb:DR64_7908; -.
DR   KEGG; bxe:Bxe_C0539; -.
DR   PATRIC; fig|266265.5.peg.8299; -.
DR   eggNOG; ENOG4108Q79; Bacteria.
DR   eggNOG; COG0363; LUCA.
DR   HOGENOM; HOG000256284; -.
DR   KO; K01057; -.
DR   OMA; LVYHTTT; -.
DR   OrthoDB; 1828393at2; -.
DR   BioCyc; BXEN266265:BXE_RS39215-MONOMER; -.
DR   UniPathway; UPA00115; UER00409.
DR   Proteomes; UP000001817; Chromosome 3.
DR   GO; GO:0017057; F:6-phosphogluconolactonase activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0005975; P:carbohydrate metabolic process; IEA:UniProtKB-UniRule.
DR   GO; GO:0006098; P:pentose-phosphate shunt; IEA:UniProtKB-UniPathway.
DR   CDD; cd01400; 6PGL; 1.
DR   InterPro; IPR005900; 6-phosphogluconolactonase_DevB.
DR   InterPro; IPR006148; Glc/Gal-6P_isomerase.
DR   InterPro; IPR037171; NagB/RpiA_transferase-like.
DR   InterPro; IPR039104; PGLS.
DR   PANTHER; PTHR11054; PTHR11054; 1.
DR   Pfam; PF01182; Glucosamine_iso; 1.
DR   SUPFAM; SSF100950; SSF100950; 1.
DR   TIGRFAMs; TIGR01198; pgl; 1.
PE   3: Inferred from homology;
DR   PRODOM; Q13HK0.
DR   SWISS-2DPAGE; Q13HK0.
KW   Complete proteome {ECO:0000313|Proteomes:UP000001817};
KW   Hydrolase {ECO:0000256|RuleBase:RU365095,
KW   ECO:0000313|EMBL:ABE36439.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001817}.
FT   DOMAIN       19    210       Glucosamine_iso. {ECO:0000259|Pfam:
FT                                PF01182}.
SQ   SEQUENCE   234 AA;  24866 MW;  18D536C52C1E9F92 CRC64;
     MITLYEFDDQ QSQSNALAKA VGDALQVSLT AQAASAAKGP GHVTLAVSGG SSPRPFLQTL
     STQPFDWARI AVTLVDDRWV AETDSASNAR FVREALLQHA ASSAVFWPLV DTAQALDAHV
     AALNADPARL LPDIAVLGMG EDGHTASIFA DSPEWDDAIT TTAHFIAVHP GSAQHARVSL
     SLSALKRIDH LFLLIAGPRK RDVLKAATST LQRNAISQLA HASEAQLNVY WSAN
//

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