(data stored in SCRATCH zone)

SWISSPROT: Q13I43_PARXL

ID   Q13I43_PARXL            Unreviewed;       269 AA.
AC   Q13I43;
DT   22-AUG-2006, integrated into UniProtKB/TrEMBL.
DT   22-AUG-2006, sequence version 1.
DT   08-MAY-2019, entry version 81.
DE   SubName: Full=3-hydroxyacyl-CoA dehydrogenase {ECO:0000313|EMBL:ABE36246.1};
DE            EC=1.1.1.35 {ECO:0000313|EMBL:ABE36246.1};
GN   ORFNames=Bxe_C0331 {ECO:0000313|EMBL:ABE36246.1};
OS   Paraburkholderia xenovorans (strain LB400).
OC   Bacteria; Proteobacteria; Betaproteobacteria; Burkholderiales;
OC   Burkholderiaceae; Paraburkholderia.
OX   NCBI_TaxID=266265 {ECO:0000313|EMBL:ABE36246.1, ECO:0000313|Proteomes:UP000001817};
RN   [1] {ECO:0000313|EMBL:ABE36246.1, ECO:0000313|Proteomes:UP000001817}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=LB400 {ECO:0000313|EMBL:ABE36246.1,
RC   ECO:0000313|Proteomes:UP000001817};
RX   PubMed=17030797; DOI=10.1073/pnas.0606924103;
RA   Chain P.S., Denef V.J., Konstantinidis K.T., Vergez L.M., Agullo L.,
RA   Reyes V.L., Hauser L., Cordova M., Gomez L., Gonzalez M., Land M.,
RA   Lao V., Larimer F., LiPuma J.J., Mahenthiralingam E., Malfatti S.A.,
RA   Marx C.J., Parnell J.J., Ramette A., Richardson P., Seeger M.,
RA   Smith D., Spilker T., Sul W.J., Tsoi T.V., Ulrich L.E., Zhulin I.B.,
RA   Tiedje J.M.;
RT   "Burkholderia xenovorans LB400 harbors a multi-replicon, 9.73-Mbp
RT   genome shaped for versatility.";
RL   Proc. Natl. Acad. Sci. U.S.A. 103:15280-15287(2006).
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DR   EMBL; CP000272; ABE36246.1; -; Genomic_DNA.
DR   STRING; 266265.Bxe_C0331; -.
DR   EnsemblBacteria; ABE36246; ABE36246; Bxe_C0331.
DR   KEGG; bxe:Bxe_C0331; -.
DR   eggNOG; ENOG4105DYT; Bacteria.
DR   eggNOG; COG1250; LUCA.
DR   HOGENOM; HOG000141498; -.
DR   KO; K00074; -.
DR   OMA; CKLGFGH; -.
DR   Proteomes; UP000001817; Chromosome 3.
DR   GO; GO:0003857; F:3-hydroxyacyl-CoA dehydrogenase activity; IEA:UniProtKB-EC.
DR   GO; GO:0070403; F:NAD+ binding; IEA:InterPro.
DR   GO; GO:0006631; P:fatty acid metabolic process; IEA:InterPro.
DR   Gene3D; 1.10.1040.10; -; 1.
DR   InterPro; IPR022694; 3-OHacyl-CoA_DH.
DR   InterPro; IPR006176; 3-OHacyl-CoA_DH_NAD-bd.
DR   InterPro; IPR006108; 3HC_DH_C.
DR   InterPro; IPR008927; 6-PGluconate_DH-like_C_sf.
DR   InterPro; IPR013328; 6PGD_dom2.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   Pfam; PF00725; 3HCDH; 1.
DR   Pfam; PF02737; 3HCDH_N; 1.
DR   PIRSF; PIRSF000105; HCDH; 1.
DR   SUPFAM; SSF48179; SSF48179; 1.
DR   SUPFAM; SSF51735; SSF51735; 1.
PE   4: Predicted;
DR   PRODOM; Q13I43.
DR   SWISS-2DPAGE; Q13I43.
KW   Complete proteome {ECO:0000313|Proteomes:UP000001817};
KW   Oxidoreductase {ECO:0000313|EMBL:ABE36246.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001817}.
FT   DOMAIN        1    170       3HCDH_N. {ECO:0000259|Pfam:PF02737}.
FT   DOMAIN      173    269       3HCDH. {ECO:0000259|Pfam:PF00725}.
FT   BINDING      36     36       Coenzyme A. {ECO:0000256|PIRSR:
FT                                PIRSR000105-3}.
FT   BINDING      43     43       Coenzyme A. {ECO:0000256|PIRSR:
FT                                PIRSR000105-3}.
FT   BINDING     106    106       Coenzyme A. {ECO:0000256|PIRSR:
FT                                PIRSR000105-3}.
FT   SITE        127    127       Important for catalytic activity.
FT                                {ECO:0000256|PIRSR:PIRSR000105-1}.
SQ   SEQUENCE   269 AA;  28917 MW;  3F80B7C49B984523 CRC64;
     MGNGIAQVCA IAGLPVSMID VSETAIERGL RAIDTSLDAL VRKERLSEVE KQAALARVSG
     TVDYDALAGA DLVIEAATEN LPLKLRILRQ IDGIISGSGV VSTNTSSISI TQLAAVLDRP
     ERFVGLHFFN PVPVMPLVEV IRGLQTSDET HAFAIGFAEV IGKTPVTVRN HPGFTVNRIL
     VPMINEAIFV LQERLATADD IDLGMRLGCN HPIGPLALAD LIGLDTLLAV MEVLHDGFRD
     SKYRPAPLLK EMVDAGRLGR KSGHGFYSY
//

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