(data stored in SCRATCH zone)

SWISSPROT: Q13QS7_PARXL

ID   Q13QS7_PARXL            Unreviewed;       132 AA.
AC   Q13QS7;
DT   22-AUG-2006, integrated into UniProtKB/TrEMBL.
DT   22-AUG-2006, sequence version 1.
DT   07-JUN-2017, entry version 74.
DE   RecName: Full=4a-hydroxytetrahydrobiopterin dehydratase {ECO:0000256|SAAS:SAAS00686659};
DE            EC=4.2.1.96 {ECO:0000256|SAAS:SAAS00686659};
GN   Name=pcbD {ECO:0000313|EMBL:ABE33562.1};
GN   ORFNames=Bxe_B2429 {ECO:0000313|EMBL:ABE33562.1};
OS   Paraburkholderia xenovorans (strain LB400).
OC   Bacteria; Proteobacteria; Betaproteobacteria; Burkholderiales;
OC   Burkholderiaceae; Paraburkholderia.
OX   NCBI_TaxID=266265 {ECO:0000313|EMBL:ABE33562.1, ECO:0000313|Proteomes:UP000001817};
RN   [1] {ECO:0000313|EMBL:ABE33562.1, ECO:0000313|Proteomes:UP000001817}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=LB400 {ECO:0000313|EMBL:ABE33562.1,
RC   ECO:0000313|Proteomes:UP000001817};
RX   PubMed=17030797; DOI=10.1073/pnas.0606924103;
RA   Chain P.S.G., Denef V.J., Konstantinidis K.T., Vergez L.M., Agullo L.,
RA   Reyes V.L., Hauser L., Cordova M., Gomez L., Gonzalez M., Land M.,
RA   Lao V., Larimer F., LiPuma J.J., Mahenthiralingam E., Malfatti S.A.,
RA   Marx C.J., Parnell J.J., Ramette A., Richardson P., Seeger M.,
RA   Smith D., Spilker T., Sul W.J., Tsoi T.V., Ulrich L.E., Zhulin I.B.,
RA   Tiedje J.M.;
RT   "Burkholderia xenovorans LB400 harbors a multi-replicon, 9.73-Mbp
RT   genome shaped for versatility.";
RL   Proc. Natl. Acad. Sci. U.S.A. 103:15280-15287(2006).
CC   -!- CATALYTIC ACTIVITY: (6R)-6-(L-erythro-1,2-dihydroxypropyl)-
CC       5,6,7,8-tetrahydro-4a-hydroxypterin = (6R)-6-(L-erythro-1,2-
CC       dihydroxypropyl)-7,8-dihydro-6H-pterin + H(2)O.
CC       {ECO:0000256|SAAS:SAAS00686665}.
CC   -!- SIMILARITY: Belongs to the pterin-4-alpha-carbinolamine
CC       dehydratase family. {ECO:0000256|SAAS:SAAS00686664}.
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DR   EMBL; CP000271; ABE33562.1; -; Genomic_DNA.
DR   RefSeq; WP_011490926.1; NZ_CP008762.1.
DR   ProteinModelPortal; Q13QS7; -.
DR   STRING; 266265.Bxe_B2429; -.
DR   EnsemblBacteria; ABE33562; ABE33562; Bxe_B2429.
DR   GeneID; 4007075; -.
DR   KEGG; bxb:DR64_4757; -.
DR   KEGG; bxe:Bxe_B2429; -.
DR   PATRIC; fig|266265.5.peg.5280; -.
DR   eggNOG; ENOG4108ZCD; Bacteria.
DR   eggNOG; COG2154; LUCA.
DR   HOGENOM; HOG000007680; -.
DR   KO; K01724; -.
DR   OMA; AWHHPDI; -.
DR   OrthoDB; POG091H05H0; -.
DR   Proteomes; UP000001817; Chromosome 2.
DR   GO; GO:0008124; F:4-alpha-hydroxytetrahydrobiopterin dehydratase activity; IEA:UniProtKB-EC.
DR   GO; GO:0006729; P:tetrahydrobiopterin biosynthetic process; IEA:InterPro.
DR   Gene3D; 3.30.1360.20; -; 1.
DR   InterPro; IPR001533; Trans/pterin_deHydtase.
DR   Pfam; PF01329; Pterin_4a; 1.
DR   SUPFAM; SSF55248; SSF55248; 1.
PE   3: Inferred from homology;
DR   PRODOM; Q13QS7.
DR   SWISS-2DPAGE; Q13QS7.
KW   Complete proteome {ECO:0000313|Proteomes:UP000001817};
KW   Lyase {ECO:0000256|SAAS:SAAS00686667, ECO:0000313|EMBL:ABE33562.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001817}.
SQ   SEQUENCE   132 AA;  15119 MW;  D8904F975445D1B5 CRC64;
     MANAERVYSD EEIQQRLVGP LQHWYLEEGW LRRKYRTEGW KGTLMVVNAV GHLAEAAWHH
     PDLTVSYAFV TVKLKTHSAK GITDKDFALA SKIESFIQWQ PATEGGPLEG TPTDDQRFRY
     IKYDKPKDPG SD
//

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