(data stored in SCRATCH zone)

SWISSPROT: Q144V8_PARXL

ID   Q144V8_PARXL            Unreviewed;       519 AA.
AC   Q144V8;
DT   22-AUG-2006, integrated into UniProtKB/TrEMBL.
DT   22-AUG-2006, sequence version 1.
DT   08-MAY-2019, entry version 78.
DE   SubName: Full=Mannose-6-phosphate isomerase, type 2 / mannose-1-phosphate guanylyltransferase (GDP) {ECO:0000313|EMBL:ABE29131.1};
DE            EC=2.7.7.22 {ECO:0000313|EMBL:ABE29131.1};
DE            EC=5.3.1.8 {ECO:0000313|EMBL:ABE29131.1};
GN   ORFNames=Bxe_A3867 {ECO:0000313|EMBL:ABE29131.1};
OS   Paraburkholderia xenovorans (strain LB400).
OC   Bacteria; Proteobacteria; Betaproteobacteria; Burkholderiales;
OC   Burkholderiaceae; Paraburkholderia.
OX   NCBI_TaxID=266265 {ECO:0000313|EMBL:ABE29131.1, ECO:0000313|Proteomes:UP000001817};
RN   [1] {ECO:0000313|EMBL:ABE29131.1, ECO:0000313|Proteomes:UP000001817}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=LB400 {ECO:0000313|EMBL:ABE29131.1,
RC   ECO:0000313|Proteomes:UP000001817};
RX   PubMed=17030797; DOI=10.1073/pnas.0606924103;
RA   Chain P.S., Denef V.J., Konstantinidis K.T., Vergez L.M., Agullo L.,
RA   Reyes V.L., Hauser L., Cordova M., Gomez L., Gonzalez M., Land M.,
RA   Lao V., Larimer F., LiPuma J.J., Mahenthiralingam E., Malfatti S.A.,
RA   Marx C.J., Parnell J.J., Ramette A., Richardson P., Seeger M.,
RA   Smith D., Spilker T., Sul W.J., Tsoi T.V., Ulrich L.E., Zhulin I.B.,
RA   Tiedje J.M.;
RT   "Burkholderia xenovorans LB400 harbors a multi-replicon, 9.73-Mbp
RT   genome shaped for versatility.";
RL   Proc. Natl. Acad. Sci. U.S.A. 103:15280-15287(2006).
CC   -!- SIMILARITY: Belongs to the mannose-6-phosphate isomerase type 2
CC       family. {ECO:0000256|RuleBase:RU004190}.
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DR   EMBL; CP000270; ABE29131.1; -; Genomic_DNA.
DR   RefSeq; WP_011486948.1; NZ_CP008760.1.
DR   STRING; 266265.Bxe_A3867; -.
DR   EnsemblBacteria; ABE29131; ABE29131; Bxe_A3867.
DR   GeneID; 4002480; -.
DR   KEGG; bxb:DR64_1543; -.
DR   KEGG; bxe:Bxe_A3867; -.
DR   PATRIC; fig|266265.5.peg.618; -.
DR   eggNOG; ENOG4105CJT; Bacteria.
DR   eggNOG; COG0662; LUCA.
DR   eggNOG; COG0836; LUCA.
DR   HOGENOM; HOG000153549; -.
DR   KO; K16011; -.
DR   OMA; ACVGTTN; -.
DR   OrthoDB; 224217at2; -.
DR   BioCyc; BXEN266265:BXE_RS02930-MONOMER; -.
DR   Proteomes; UP000001817; Chromosome 1.
DR   GO; GO:0008928; F:mannose-1-phosphate guanylyltransferase (GDP) activity; IEA:UniProtKB-EC.
DR   GO; GO:0004476; F:mannose-6-phosphate isomerase activity; IEA:UniProtKB-EC.
DR   GO; GO:0000271; P:polysaccharide biosynthetic process; IEA:InterPro.
DR   Gene3D; 2.60.120.10; -; 1.
DR   Gene3D; 3.90.550.10; -; 1.
DR   InterPro; IPR006375; Man1P_GuaTrfase/Man6P_Isoase.
DR   InterPro; IPR001538; Man6P_isomerase-2_C.
DR   InterPro; IPR005835; NTP_transferase_dom.
DR   InterPro; IPR029044; Nucleotide-diphossugar_trans.
DR   InterPro; IPR014710; RmlC-like_jellyroll.
DR   InterPro; IPR011051; RmlC_Cupin_sf.
DR   Pfam; PF01050; MannoseP_isomer; 1.
DR   Pfam; PF00483; NTP_transferase; 1.
DR   SUPFAM; SSF51182; SSF51182; 1.
DR   SUPFAM; SSF53448; SSF53448; 1.
DR   TIGRFAMs; TIGR01479; GMP_PMI; 1.
PE   3: Inferred from homology;
DR   PRODOM; Q144V8.
DR   SWISS-2DPAGE; Q144V8.
KW   Complete proteome {ECO:0000313|Proteomes:UP000001817};
KW   Isomerase {ECO:0000313|EMBL:ABE29131.1};
KW   Nucleotidyltransferase {ECO:0000313|EMBL:ABE29131.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001817};
KW   Transferase {ECO:0000313|EMBL:ABE29131.1}.
FT   DOMAIN       31    335       NTP_transferase. {ECO:0000259|Pfam:
FT                                PF00483}.
FT   DOMAIN      363    513       MannoseP_isomer. {ECO:0000259|Pfam:
FT                                PF01050}.
SQ   SEQUENCE   519 AA;  55558 MW;  8D816BA156FBF615 CRC64;
     MLTQAAMSAL SIDPNSAGAA TAHGRCARIV PVILAGGSGT RLWPVSRENY PKQLIDVVGS
     DSLLQATARR MDGFPAGWKV DASPVIVCGE EHRFVIAEQL HENGVDARLI VEPARRDTAP
     ALTLAASLAC ADGGDAILVV MPADHSIADV PALQAALERA AQYAEQGSIA TLGVPPTRPD
     TGFGYIRIGA ELAGGGHAID GFVEKPAEEL AAKYVAAGMY WWNSGIFIVR ASVWLDTLKR
     LQPEMHSACE RAFSGGRQDG AYFRPLVEAF LSAPANSIDY AVMERLTETA EPDATDGAAA
     SAPAQPAGVV IGLDAGWSDL GSWDAVWAAM EKDANGNAGR GRVTFEGAVS SYAHSEGRLV
     ACVGTTNVVV VETADAVLVV DRSHVQDVKG LVSRIKAQHA PEADAHRKVR RPWGFYDSID
     HGERFQVKRI VVTPGAQLSL QLHHHRAEHW VVVRGTALVT RGDEQFLLSE NESTYIPLGT
     RHRLENPGKV PLEIIEIQSG TYLGEDDIVR FNDNYGRCS
//

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