(data stored in SCRATCH zone)

SWISSPROT: Q145Q2_PARXL

ID   Q145Q2_PARXL            Unreviewed;       531 AA.
AC   Q145Q2;
DT   22-AUG-2006, integrated into UniProtKB/TrEMBL.
DT   22-AUG-2006, sequence version 1.
DT   08-MAY-2019, entry version 71.
DE   SubName: Full=Major facilitator superfamily (MFS) multidrug efflux pump, EmrB/QacA subfamily {ECO:0000313|EMBL:ABE28937.1};
GN   ORFNames=Bxe_A4062 {ECO:0000313|EMBL:ABE28937.1};
OS   Paraburkholderia xenovorans (strain LB400).
OC   Bacteria; Proteobacteria; Betaproteobacteria; Burkholderiales;
OC   Burkholderiaceae; Paraburkholderia.
OX   NCBI_TaxID=266265 {ECO:0000313|EMBL:ABE28937.1, ECO:0000313|Proteomes:UP000001817};
RN   [1] {ECO:0000313|EMBL:ABE28937.1, ECO:0000313|Proteomes:UP000001817}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=LB400 {ECO:0000313|EMBL:ABE28937.1,
RC   ECO:0000313|Proteomes:UP000001817};
RX   PubMed=17030797; DOI=10.1073/pnas.0606924103;
RA   Chain P.S., Denef V.J., Konstantinidis K.T., Vergez L.M., Agullo L.,
RA   Reyes V.L., Hauser L., Cordova M., Gomez L., Gonzalez M., Land M.,
RA   Lao V., Larimer F., LiPuma J.J., Mahenthiralingam E., Malfatti S.A.,
RA   Marx C.J., Parnell J.J., Ramette A., Richardson P., Seeger M.,
RA   Smith D., Spilker T., Sul W.J., Tsoi T.V., Ulrich L.E., Zhulin I.B.,
RA   Tiedje J.M.;
RT   "Burkholderia xenovorans LB400 harbors a multi-replicon, 9.73-Mbp
RT   genome shaped for versatility.";
RL   Proc. Natl. Acad. Sci. U.S.A. 103:15280-15287(2006).
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DR   EMBL; CP000270; ABE28937.1; -; Genomic_DNA.
DR   RefSeq; WP_011486764.1; NZ_CP008760.1.
DR   STRING; 266265.Bxe_A4062; -.
DR   EnsemblBacteria; ABE28937; ABE28937; Bxe_A4062.
DR   GeneID; 4002207; -.
DR   KEGG; bxb:DR64_1739; -.
DR   KEGG; bxe:Bxe_A4062; -.
DR   PATRIC; fig|266265.5.peg.422; -.
DR   eggNOG; ENOG4105C0R; Bacteria.
DR   eggNOG; ENOG410XNN3; LUCA.
DR   HOGENOM; HOG000239126; -.
DR   OMA; GFGMSPK; -.
DR   OrthoDB; 1558246at2; -.
DR   BioCyc; BXEN266265:BXE_RS02000-MONOMER; -.
DR   Proteomes; UP000001817; Chromosome 1.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0055085; P:transmembrane transport; IEA:InterPro.
DR   CDD; cd06174; MFS; 1.
DR   InterPro; IPR011701; MFS.
DR   InterPro; IPR020846; MFS_dom.
DR   InterPro; IPR036259; MFS_trans_sf.
DR   InterPro; IPR001411; Tet-R_TetB/Drug-R_transptr.
DR   PANTHER; PTHR23501; PTHR23501; 1.
DR   Pfam; PF07690; MFS_1; 1.
DR   SUPFAM; SSF103473; SSF103473; 1.
DR   PROSITE; PS50850; MFS; 1.
PE   4: Predicted;
DR   PRODOM; Q145Q2.
DR   SWISS-2DPAGE; Q145Q2.
KW   Complete proteome {ECO:0000313|Proteomes:UP000001817};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001817};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM     21     45       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM     57     76       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM     88    114       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    120    138       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    150    173       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    179    197       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    236    257       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    278    302       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    314    332       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    344    364       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    370    394       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    415    434       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    489    510       Helical. {ECO:0000256|SAM:Phobius}.
FT   DOMAIN       23    514       MFS. {ECO:0000259|PROSITE:PS50850}.
SQ   SEQUENCE   531 AA;  57001 MW;  F4F79D7E9FDAB449 CRC64;
     MAVHTAAHHS SGQVLPFRES LLAMLGISFV TMLVALDQTV VGTALPTIVA ELKGFELYAW
     VATSYLLTSV ITVPIFGRLG DYYGRKPFVI ASIVVFTGAS VLCGAANNML FLVLARGLQG
     IGGGMLVGTA FACIPDLFPD SVVRLRWQVV MSSAFGIANA VGPSLGGFLT QYYGWRSVFY
     VNLPVGLLSL FFVWRFLPHL RHVEHEGKMR LDWPGAVLIA VALGSLQLFV ELLPKHGVTL
     SVAALLALSA ASAYALWQWE KRCPTAILPV DMFRNRSLAA LFTLAVLGGF TMFSLLFYAP
     LLFQGGFGMS PKEAGLVITP LVVFITIGSI ANGRIVSRVR NPNLMLYVGF TLLALACLGV
     VVATRAMPQW LLMAFMVVGG LGLGFVMPNL TIFAQQTAGR EHLGIATALL QSLRMIGGML
     GTALTGTLVS HMYASGVRSA LENDHASHWF ADLGDPQILI NRDAQTTLLG QLAHAGHNGA
     MLLESAREAL VSAIHLGLAM AAIIAVVSVW QSRRVPPIKL QRKLEPVIHA D
//

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