(data stored in SCRATCH zone)

SWISSPROT: Q145Y5_PARXL

ID   Q145Y5_PARXL            Unreviewed;       307 AA.
AC   Q145Y5;
DT   22-AUG-2006, integrated into UniProtKB/TrEMBL.
DT   22-AUG-2006, sequence version 1.
DT   08-MAY-2019, entry version 94.
DE   RecName: Full=RNA polymerase sigma factor RpoH {ECO:0000256|HAMAP-Rule:MF_00961};
DE   AltName: Full=RNA polymerase sigma-32 factor {ECO:0000256|HAMAP-Rule:MF_00961};
GN   Name=rpoH {ECO:0000256|HAMAP-Rule:MF_00961};
GN   ORFNames=Bxe_A4146 {ECO:0000313|EMBL:ABE28854.1};
OS   Paraburkholderia xenovorans (strain LB400).
OC   Bacteria; Proteobacteria; Betaproteobacteria; Burkholderiales;
OC   Burkholderiaceae; Paraburkholderia.
OX   NCBI_TaxID=266265 {ECO:0000313|EMBL:ABE28854.1, ECO:0000313|Proteomes:UP000001817};
RN   [1] {ECO:0000313|EMBL:ABE28854.1, ECO:0000313|Proteomes:UP000001817}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=LB400 {ECO:0000313|EMBL:ABE28854.1,
RC   ECO:0000313|Proteomes:UP000001817};
RX   PubMed=17030797; DOI=10.1073/pnas.0606924103;
RA   Chain P.S., Denef V.J., Konstantinidis K.T., Vergez L.M., Agullo L.,
RA   Reyes V.L., Hauser L., Cordova M., Gomez L., Gonzalez M., Land M.,
RA   Lao V., Larimer F., LiPuma J.J., Mahenthiralingam E., Malfatti S.A.,
RA   Marx C.J., Parnell J.J., Ramette A., Richardson P., Seeger M.,
RA   Smith D., Spilker T., Sul W.J., Tsoi T.V., Ulrich L.E., Zhulin I.B.,
RA   Tiedje J.M.;
RT   "Burkholderia xenovorans LB400 harbors a multi-replicon, 9.73-Mbp
RT   genome shaped for versatility.";
RL   Proc. Natl. Acad. Sci. U.S.A. 103:15280-15287(2006).
CC   -!- FUNCTION: Sigma factors are initiation factors that promote the
CC       attachment of RNA polymerase to specific initiation sites and are
CC       then released. This sigma factor is involved in regulation of
CC       expression of heat shock genes. {ECO:0000256|HAMAP-Rule:MF_00961}.
CC   -!- SUBUNIT: Interacts with the RNA polymerase core enzyme.
CC       {ECO:0000256|HAMAP-Rule:MF_00961}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00961}.
CC   -!- SIMILARITY: Belongs to the sigma-70 factor family. RpoH subfamily.
CC       {ECO:0000256|HAMAP-Rule:MF_00961}.
CC   -!- CAUTION: Lacks conserved residue(s) required for the propagation
CC       of feature annotation. {ECO:0000256|HAMAP-Rule:MF_00961}.
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DR   EMBL; CP000270; ABE28854.1; -; Genomic_DNA.
DR   STRING; 266265.Bxe_A4146; -.
DR   EnsemblBacteria; ABE28854; ABE28854; Bxe_A4146.
DR   KEGG; bxe:Bxe_A4146; -.
DR   eggNOG; ENOG4105DEK; Bacteria.
DR   eggNOG; COG0568; LUCA.
DR   HOGENOM; HOG000270269; -.
DR   KO; K03089; -.
DR   OMA; YQRWLAE; -.
DR   Proteomes; UP000001817; Chromosome 1.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0016987; F:sigma factor activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0009408; P:response to heat; IEA:UniProtKB-UniRule.
DR   GO; GO:0001123; P:transcription initiation from bacterial-type RNA polymerase promoter; IEA:UniProtKB-UniRule.
DR   HAMAP; MF_00961; Sigma70_RpoH; 1.
DR   InterPro; IPR014284; RNA_pol_sigma-70_dom.
DR   InterPro; IPR000943; RNA_pol_sigma70.
DR   InterPro; IPR009042; RNA_pol_sigma70_r1_2.
DR   InterPro; IPR007627; RNA_pol_sigma70_r2.
DR   InterPro; IPR007630; RNA_pol_sigma70_r4.
DR   InterPro; IPR013325; RNA_pol_sigma_r2.
DR   InterPro; IPR013324; RNA_pol_sigma_r3/r4-like.
DR   InterPro; IPR012759; RNA_pol_sigma_RpoH_proteobac.
DR   Pfam; PF00140; Sigma70_r1_2; 1.
DR   Pfam; PF04542; Sigma70_r2; 1.
DR   Pfam; PF04545; Sigma70_r4; 1.
DR   PRINTS; PR00046; SIGMA70FCT.
DR   SUPFAM; SSF88659; SSF88659; 1.
DR   SUPFAM; SSF88946; SSF88946; 1.
DR   TIGRFAMs; TIGR02392; rpoH_proteo; 1.
DR   TIGRFAMs; TIGR02937; sigma70-ECF; 1.
DR   PROSITE; PS00715; SIGMA70_1; 1.
DR   PROSITE; PS00716; SIGMA70_2; 1.
PE   3: Inferred from homology;
DR   PRODOM; Q145Y5.
DR   SWISS-2DPAGE; Q145Y5.
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Complete proteome {ECO:0000313|Proteomes:UP000001817};
KW   Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00961};
KW   DNA-binding {ECO:0000256|HAMAP-Rule:MF_00961,
KW   ECO:0000256|SAAS:SAAS00611263};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001817};
KW   Sigma factor {ECO:0000256|HAMAP-Rule:MF_00961,
KW   ECO:0000256|SAAS:SAAS00611278};
KW   Stress response {ECO:0000256|HAMAP-Rule:MF_00961};
KW   Transcription {ECO:0000256|HAMAP-Rule:MF_00961,
KW   ECO:0000256|SAAS:SAAS00611290};
KW   Transcription regulation {ECO:0000256|HAMAP-Rule:MF_00961,
KW   ECO:0000256|SAAS:SAAS00611294}.
FT   DOMAIN       96    109       RNA_pol_sigma70. {ECO:0000259|PROSITE:
FT                                PS00715}.
FT   DOMAIN      273    299       RNA_pol_sigma70. {ECO:0000259|PROSITE:
FT                                PS00716}.
FT   DNA_BIND    274    293       H-T-H motif. {ECO:0000256|HAMAP-Rule:
FT                                MF_00961}.
FT   REGION       72    141       Sigma-70 factor domain-2.
FT                                {ECO:0000256|HAMAP-Rule:MF_00961}.
FT   COILED      173    193       {ECO:0000256|SAM:Coils}.
FT   MOTIF        96     99       Interaction with polymerase core subunit
FT                                RpoC. {ECO:0000256|HAMAP-Rule:MF_00961}.
SQ   SEQUENCE   307 AA;  33998 MW;  92CF63B739FC4380 CRC64;
     MTLPSTLSPS SAKAASAGAL ALSHSSLLPG QLGNIDAYIQ AVNRIPMLTP AEERQFATEF
     REQDNLESAR RLVLSHLRLV VSIARNYLGY GLPHADLIQE GNIGLMKAVK RFDPEQNVRL
     VSYAMHWIKA EIHEYILRNW RMVKVATTKA QRKLFFNLRS HKQGLGAFTP DEIEGLAKEL
     NVKREEVSEM ETRLSGGDIA LEGQVEDGEE SYAPIAYLAD SHSEPTAVLA SRQRDKLQSD
     GIASALDALD ARSRRIIEAR WLKVEDDGSG GSTLHELADE FGVSAERIRQ IEASAMKKMR
     GALTEYA
//

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