(data stored in SCRATCH zone)

SWISSPROT: Q146Z9_PARXL

ID   Q146Z9_PARXL            Unreviewed;       800 AA.
AC   Q146Z9;
DT   22-AUG-2006, integrated into UniProtKB/TrEMBL.
DT   22-AUG-2006, sequence version 1.
DT   08-MAY-2019, entry version 97.
DE   SubName: Full=Multi-sensor signal transduction histidine kinase {ECO:0000313|EMBL:ABE28590.1};
DE            EC=2.7.13.3 {ECO:0000313|EMBL:ABE28590.1};
GN   ORFNames=Bxe_A4410 {ECO:0000313|EMBL:ABE28590.1};
OS   Paraburkholderia xenovorans (strain LB400).
OC   Bacteria; Proteobacteria; Betaproteobacteria; Burkholderiales;
OC   Burkholderiaceae; Paraburkholderia.
OX   NCBI_TaxID=266265 {ECO:0000313|EMBL:ABE28590.1, ECO:0000313|Proteomes:UP000001817};
RN   [1] {ECO:0000313|EMBL:ABE28590.1, ECO:0000313|Proteomes:UP000001817}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=LB400 {ECO:0000313|EMBL:ABE28590.1,
RC   ECO:0000313|Proteomes:UP000001817};
RX   PubMed=17030797; DOI=10.1073/pnas.0606924103;
RA   Chain P.S., Denef V.J., Konstantinidis K.T., Vergez L.M., Agullo L.,
RA   Reyes V.L., Hauser L., Cordova M., Gomez L., Gonzalez M., Land M.,
RA   Lao V., Larimer F., LiPuma J.J., Mahenthiralingam E., Malfatti S.A.,
RA   Marx C.J., Parnell J.J., Ramette A., Richardson P., Seeger M.,
RA   Smith D., Spilker T., Sul W.J., Tsoi T.V., Ulrich L.E., Zhulin I.B.,
RA   Tiedje J.M.;
RT   "Burkholderia xenovorans LB400 harbors a multi-replicon, 9.73-Mbp
RT   genome shaped for versatility.";
RL   Proc. Natl. Acad. Sci. U.S.A. 103:15280-15287(2006).
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=ATP + protein L-histidine = ADP + protein N-phospho-L-
CC         histidine.; EC=2.7.13.3;
CC         Evidence={ECO:0000256|SAAS:SAAS01126420};
CC   -----------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   -----------------------------------------------------------------------
DR   EMBL; CP000270; ABE28590.1; -; Genomic_DNA.
DR   STRING; 266265.Bxe_A4410; -.
DR   EnsemblBacteria; ABE28590; ABE28590; Bxe_A4410.
DR   KEGG; bxe:Bxe_A4410; -.
DR   eggNOG; ENOG4105ES5; Bacteria.
DR   eggNOG; COG5000; LUCA.
DR   HOGENOM; HOG000266158; -.
DR   OMA; FARMPEP; -.
DR   Proteomes; UP000001817; Chromosome 1.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR   CDD; cd06225; HAMP; 1.
DR   CDD; cd00075; HATPase_c; 1.
DR   CDD; cd00082; HisKA; 1.
DR   Gene3D; 3.30.565.10; -; 1.
DR   InterPro; IPR003660; HAMP_dom.
DR   InterPro; IPR003594; HATPase_C.
DR   InterPro; IPR036890; HATPase_C_sf.
DR   InterPro; IPR005467; His_kinase_dom.
DR   InterPro; IPR003661; HisK_dim/P.
DR   InterPro; IPR036097; HisK_dim/P_sf.
DR   InterPro; IPR000014; PAS.
DR   InterPro; IPR035965; PAS-like_dom_sf.
DR   InterPro; IPR004358; Sig_transdc_His_kin-like_C.
DR   InterPro; IPR017232; Sig_transdc_His_kinase_NtrY.
DR   Pfam; PF00672; HAMP; 1.
DR   Pfam; PF02518; HATPase_c; 1.
DR   Pfam; PF00512; HisKA; 1.
DR   PIRSF; PIRSF037532; STHK_NtrY; 1.
DR   PRINTS; PR00344; BCTRLSENSOR.
DR   SMART; SM00304; HAMP; 1.
DR   SMART; SM00387; HATPase_c; 1.
DR   SMART; SM00388; HisKA; 1.
DR   SMART; SM00091; PAS; 1.
DR   SUPFAM; SSF47384; SSF47384; 1.
DR   SUPFAM; SSF55785; SSF55785; 1.
DR   SUPFAM; SSF55874; SSF55874; 1.
DR   PROSITE; PS50885; HAMP; 1.
DR   PROSITE; PS50109; HIS_KIN; 1.
PE   4: Predicted;
DR   PRODOM; Q146Z9.
DR   SWISS-2DPAGE; Q146Z9.
KW   ATP-binding {ECO:0000256|SAAS:SAAS00925949};
KW   Complete proteome {ECO:0000313|Proteomes:UP000001817};
KW   Kinase {ECO:0000256|SAAS:SAAS01003914, ECO:0000313|EMBL:ABE28590.1};
KW   Membrane {ECO:0000256|SAAS:SAAS00925724, ECO:0000256|SAM:Phobius};
KW   Nucleotide-binding {ECO:0000256|SAAS:SAAS00925310};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001817};
KW   Transferase {ECO:0000256|SAAS:SAAS01003669,
KW   ECO:0000313|EMBL:ABE28590.1};
KW   Transmembrane {ECO:0000256|SAAS:SAAS00926038,
KW   ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAAS:SAAS00926160,
KW   ECO:0000256|SAM:Phobius}.
FT   TRANSMEM     12     34       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM     46     70       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM     82    104       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    306    329       Helical. {ECO:0000256|SAM:Phobius}.
FT   DOMAIN      331    383       HAMP. {ECO:0000259|PROSITE:PS50885}.
FT   DOMAIN      541    769       Histidine kinase. {ECO:0000259|PROSITE:
FT                                PS50109}.
SQ   SEQUENCE   800 AA;  86812 MW;  96AAE8DA9F6FA6E8 CRC64;
     MRSATSVSSI VVRVLVSTVA VTAVLLLVLL AAASANTEFF DRYYQWLYAA NLAVAMIFLL
     VVATLVIIII ARLRKGKFGT RLLAKLAFFM ALVGVVPGGI IYVVSYQFVS RSIESWFDVN
     VETALTSGLN LGRGMLDASL SDLQTKGRLM SEQLASADAA GTTLTLLRLR DQFGVQDATI
     VEPTRSMSGA TPDMHVVAQA SGNYATLVPN DLPTPLMIDQ ARGRGYAAIE GEVDGDPHAH
     GSKGVLRLRV VQRIPDSNAS LLQPTERFLQ LTQPVSPSLA RNADAVQRAY REYQEKALGR
     TGLRKMYIGT LTLALFLATF IAMMLALALG NQLARPLFLL AQGTKEITEG DYTPKREIKS
     RDELGFLTQS FNAMTRQLSE ARAAVENNRI ALEHSKAYLE SILANLTAGV FVFDRQFRLT
     TANRGAERIF RQPFQAVMGS ALDQIGVLSE FGGMVRKAFA DREAASGDGH DDRGHWQQQF
     SVQVPGETEP LTLLVRGARL VSATDRDAED MQTSGYVVVF DDISDVISAQ RSIAWGEVAR
     RLAHEIKNPL TPIQLSAERL QMKLADKLSP SDADVLKRGA TTIVNQVAAM KQMVDNFRDY
     ARTPPAVLAH LQLNDLVSEV LTLYGIEEGK GAIQVELAAL PAIRGDATQL RQVIHNLLQN
     AQDAVADLEH PRVLLETRTV EYGDPDAEGK VRVAVRLTVS DNGPGFSARI LTRAFEPYVT
     TKAKGTGLGL AMVKKIVDEH GARIDIRNRM KAGDVIEGAQ ISILFLQLAD DAATPGTGPR
     PAHGGASQGK TKATVQTRAA
//

If you have problems or comments...

PBIL Back to PBIL home page